2413100-40-8

2413100-40-8 structure

Name: PD-1/PD-L1-IN-13
Chemical Name: PD-1/PD-L1-IN-13
CAS Number: 2413100-40-8
Molecular Formula: C₃₆H₃₄ClF₂N₃O₉
Molecular Weight: 726.12
Catalog: Signaling Pathways Immunology/Inflammation PD-1/PD-L1
Create Date: 2022-04-06 14:15:29
Modify Date: 2024-01-09 17:55:48
PD-1/PD-L1-IN-13 (Compound 43) is a potent immune checkpoint PD-1/PD-L1 inhibitor with an IC50 value of 10.2 nM. PD-1/PD-L1-IN-13 promots CD8+ T cell activation and delays the tumor growth in the Hepa1-6 syngeneic mouse model[1].

Name	PD-1/PD-L1-IN-13

Description	PD-1/PD-L1-IN-13 (Compound 43) is a potent immune checkpoint PD-1/PD-L1 inhibitor with an IC50 value of 10.2 nM. PD-1/PD-L1-IN-13 promots CD8+ T cell activation and delays the tumor growth in the Hepa1-6 syngeneic mouse model[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Immunology/Inflammation >> PD-1/PD-L1
References	[1]. Song Z, et al. Design, Synthesis, and Pharmacological Evaluation of Biaryl-Containing PD-1/PD-L1 Interaction Inhibitors Bearing a Unique Difluoromethyleneoxy Linkage. J Med Chem. 2021;64(22):16687-16702.

Molecular Formula	C₃₆H₃₄ClF₂N₃O₉
Molecular Weight	726.12