182370-45-2
182370-45-2 structure
- Name: Idroxioleic acid
- Chemical Name: Idroxioleic acid
- CAS Number: 182370-45-2
- Molecular Formula: C18H34O3
- Molecular Weight: 298.46
- Catalog: Research Areas Cancer
- Create Date: 2022-01-17 18:51:57
- Modify Date: 2025-08-25 10:46:50
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Idroxioleic acid ((R)-2-Hydroxyoleic acid; (R)-2-OHOA), the R enantiomer of (Rac)-Idroxioleic acid, is an orally active fatty acid that modulates the lipid composition and structure of the membranes. Idroxioleic acid has antitumor activities[1].
| Name | Idroxioleic acid |
|---|
| Description | Idroxioleic acid ((R)-2-Hydroxyoleic acid; (R)-2-OHOA), the R enantiomer of (Rac)-Idroxioleic acid, is an orally active fatty acid that modulates the lipid composition and structure of the membranes. Idroxioleic acid has antitumor activities[1]. |
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| Related Catalog | |
| In Vitro | Idroxioleic acid ((R)-2-Hydroxyoleic acid; (R)-2-OHOA) inhibited the growth of A549, lung adenocarcinoma cell line with an IC50 of 252 μM[1]. |
| In Vivo | Idroxioleic acid ((R)-2-Hydroxyoleic acid; (R)-2-OHOA; 400 mg/kg; p.o.; daily; for 21 days) causes a reduction in tumor volume of about 20-25% after 21 days[1]. Animal Model: Male NUDE (Swiss) Crl:NU(Ico)-Foxn1nu mice (5 weeks old, 30-35 g) injected with A549 human lung cancer cells[1] Dosage: 400 mg/kg Administration: p.o.; daily; for 21 days Result: Caused a reduction in tumor volume of about 20-25% after 21 days. |
| References |
| Molecular Formula | C18H34O3 |
|---|---|
| Molecular Weight | 298.46 |