JF669, SE

Modify Date: 2024-01-12 10:40:29

JF669, SE Structure
JF669, SE structure
Common Name JF669, SE
CAS Number 2127150-20-1 Molecular Weight 693.76
Density N/A Boiling Point N/A
Molecular Formula C34H30F3N3O6SSi Melting Point N/A
MSDS N/A Flash Point N/A

 Use of JF669, SE


JF669, SE, a red fluorescent dye, can be directly reacted with the available thiol-containing HaloTag ligand under mild conditions (DIEA, DMF) to afford a JF669−HaloTag ligand in a single step (Ex = 669 nm; Em = 682 nm)[1].

 Names

Name JF669, SE

 JF669, SE Biological Activity

Description JF669, SE, a red fluorescent dye, can be directly reacted with the available thiol-containing HaloTag ligand under mild conditions (DIEA, DMF) to afford a JF669−HaloTag ligand in a single step (Ex = 669 nm; Em = 682 nm)[1].
Related Catalog
In Vitro JF669 undergoes rapid conversion to thioether product (<5 min to completion) in organic solvents, where the dye predominantly adopts the closed form[1]. JF669 displays comparatively excellent photostability, retaining 97% fluorescence after the same number of cycles[1].
References

[1]. Jonathan B Grimm, et al. General Synthetic Method for Si-Fluoresceins and Si-Rhodamines. ACS Cent Sci. 2017 Sep 27;3(9):975-985.

 Chemical & Physical Properties

Molecular Formula C34H30F3N3O6SSi
Molecular Weight 693.76