Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Fmoc-L-Dap(Poc)-OH

Fmoc-L-Dap(Poc)-OH is a click chemistry reagent containing an azide group. Amino acid building block suitable for side chain Click conjugation with standard protocols and together with tetrazine linkers in copper-free Click conjugation (Diels-Alder)[1].

  • CAS Number: 2250437-44-4
  • MF: C22H20N2O6
  • MW: 408.40
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

fmoc-glu(o-2-phipr)-oh

Fmoc-Glu(O-2-PhiPr)-OH is a glutamic acid derivative[1].

  • CAS Number: 200616-39-3
  • MF: C29H29NO6
  • MW: 487.54400
  • Catalog: Others
  • Density: 1.249
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ginkgotoxin

4'-O-Methylpyridoxine, a natural compound, possesses antioxidant activity[1].

  • CAS Number: 1464-33-1
  • MF: C9H13NO3
  • MW: 183.204
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 404.2±40.0 °C at 760 mmHg
  • Melting Point: 181°C
  • Flash Point: 198.3±27.3 °C

p-Hydroxy-5,6-dehydrokawain

p-Hydroxy-5,6-dehydrokawain is a natural compound isolated from Kawain[1].

  • CAS Number: 39986-86-2
  • MF: C14H12O4
  • MW: 244.243
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 493.0±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 192.7±22.2 °C

H-D-Met-OMe.HCl

H-D-Met-OMe.HCl is a Methionine (HY-13694) derivative[1].

  • CAS Number: 69630-60-0
  • MF: C6H14ClNO2S
  • MW: 199.699
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 240ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 99ºC

AQC

AQC (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate) is a reagent used in for amino acid or protein sequence analysis by HPLC with fluorescence detection. AQC reacts with primary and secondary amino acids to yield fluorescent derivates, allowing amino acid detection at under-picomolar levels[1][2].

  • CAS Number: 148757-94-2
  • MF: C14H11N3O4
  • MW: 315.262
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 661.0±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 353.5±34.3 °C

Mitochondrial respiration-IN-2

Mitochondrial respiration-IN-2 is the fluorine derivative of Virginiamycin M1 (HY-N6686). Mitochondrial respiration-IN-2 can inhibit mitochondrial translation of glioblastoma stem cells[1].

  • CAS Number: 318498-81-6
  • MF: C28H36FN3O6
  • MW: 529.60
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Pristane

Pristane (Norphytane) is a naturally occurring hydrocarbon oil found in small quantities in many plants, in various marine organisms, and as the most active component of mineral oil[1]. Pristane is a non-antigenic adjuvant, and induces MHC class II-restricted, arthritogenic T cells in the rat[2].

  • CAS Number: 1921-70-6
  • MF: C19H40
  • MW: 268.521
  • Catalog: Inflammation/Immunology
  • Density: 0.8±0.1 g/cm3
  • Boiling Point: 296.0±0.0 °C at 760 mmHg
  • Melting Point: -99ºC
  • Flash Point: 140.7±12.3 °C

Gliadorphin-7 trifluoroacetate salt

α-Gliadin (43-49) is the major protein component of gluten. α-Gliadin (43-49) can be used in the immunological response to α-gliadin[1].

  • CAS Number: 107936-65-2
  • MF: C43H57N9O11
  • MW: 875.96600
  • Catalog: Inflammation/Immunology
  • Density: 1.383g/cm3
  • Boiling Point: 1356ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 773.9ºC

Carboxymethyl cellulose

Cellulose carboxymethyl ether sodium is the sodium salt of cellulose arboxymethyl and frequently used as viscous agent, paste and barrier agent.

  • CAS Number: 9004-32-4
  • MF: C6H7O2(OH)2CH2COONa
  • MW:
  • Catalog: Biochemical Assay Reagents
  • Density: 1,6 g/cm3
  • Boiling Point: N/A
  • Melting Point: 274 °C (dec.)
  • Flash Point: N/A

Ninhydrin

Ninhydrin can be used as a chromogenic analytical probe for the quantification of amino acids and proteins.

  • CAS Number: 485-47-2
  • MF: C9H6O4
  • MW: 178.141
  • Catalog: Others
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 449.3±45.0 °C at 760 mmHg
  • Melting Point: 250 °C (dec.)(lit.)
  • Flash Point: 239.7±25.2 °C

GPR171 agonist TFA

BigLEN(mouse) is a GPR171 agonist. BigLEN(mouse) is a proSAAS-derived neuropeptide. BigLEN(mouse) regulates food intake in mice. BigLEN(mouse) inhibits the release of glutamate onto parvocellular neurons of the paraventricular nucleus in a process dependent upon activation of postsynaptic G proteins.

  • CAS Number: 501036-69-7
  • MF: C78H130N24O22
  • MW: 1756.01
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Emodin 1-O-beta-D-glucoside

Emodin-1-O-β-D-glucopyranoside, isolated from medicinal plant Polygonum cuspidatum Sieb. & Zucc, is a potent and noncompetitive bacterial neuraminidase (BNA) inhibitor with an IC50 of 0.85 μM[1].

  • CAS Number: 38840-23-2
  • MF: C21H20O10
  • MW: 432.37800
  • Catalog: Inflammation/Immunology
  • Density: 1.667±0.06 g/cm3
  • Boiling Point: N/A
  • Melting Point: 239-241 ºC
  • Flash Point: N/A

8-Oxyberberine

Berlambine is a natural alkaloid isolated from many plants[1].

  • CAS Number: 549-21-3
  • MF: C20H17NO5
  • MW: 351.353
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 611.5±55.0 °C at 760 mmHg
  • Melting Point: 200-201ºC
  • Flash Point: 323.6±31.5 °C

EZM 2302

EZM 2302 is an inhibitor of coactivator-associated arginine methyltransferase 1 (CARM1) with an IC50 of 6 nM.

  • CAS Number: 1628830-21-6
  • MF: C29H37ClN6O5
  • MW: 585.09
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3′,5′-Dimethoxyacetophenone

3′,5′-Dimethoxyacetophenone is a natural ketone compound with antioxidant activities. 3′,5′-Dimethoxyacetophenone is a building block in the chemical synthesis[1].

  • CAS Number: 39151-19-4
  • MF: C10H12O3
  • MW: 180.201
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 290.5±0.0 °C at 760 mmHg
  • Melting Point: 33-34 °C(lit.)
  • Flash Point: 109.0±8.2 °C

Febuxostat isopropyl isomer

Febuxostat isopropyl isomer is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a Ki of 0.6 nM[1].

  • CAS Number: 144060-52-6
  • MF: C15H14N2O3S
  • MW: 302.34826
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

FL118

(R)-FL118 (10,11-(Methylenedioxy)-20(R)-camptothecin) is the R-enantiomer of FL118 (HY-12486). (R)-FL118 shows anticancer activity[1].

  • CAS Number: 151636-76-9
  • MF: C21H16N2O6
  • MW: 392.36200
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

12-(7-NITROBENZOFURAZAN-4-YLAMINO)DODECANOIC ACID

12-(7-Nitrobenzofurazan-4-ylamino)dodecanoic acid is an amine-reactive fluorescent dye[1].

  • CAS Number: 96801-39-7
  • MF: C18H26N4O5
  • MW: 378.42300
  • Catalog: Others
  • Density: 1.26g/cm3
  • Boiling Point: 582.6ºC at 760mmHg
  • Melting Point: 79-81ºC(lit.)
  • Flash Point: 306.2ºC

Lophanthoidin B

Lophanthoidin B is a diterpenoids compound isolated from the dried leaves of Rabdosia lophanthoides[1].

  • CAS Number: 120462-42-2
  • MF: C24H32O8
  • MW: 448.506
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 564.0±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 185.4±23.6 °C

Water-18O

Water-18O is the 18O-labeled Water[1].

  • CAS Number: 14314-42-2
  • MF: H2O
  • MW: 20.01500
  • Catalog: Others
  • Density: 1.11
  • Boiling Point: 100ºC
  • Melting Point: 0ºC
  • Flash Point: N/A

TfR-T12 TFA

TfR-T12 is a BBB-penetrated transferrin receptor (TfR) binding peptide, displaying a binding affinity in the nM range[1][2].

  • CAS Number: 344618-30-0
  • MF: C71H99N19O15S
  • MW: 1490.73
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Pyrotinib Racemate

Pyrotinib Racemate is the racemate of Pyrotinib. Pyrotinib is a potent and selective EGFR/HER2 dual inhibitor.

  • CAS Number: 1246089-97-3
  • MF: C32H31ClN6O3
  • MW: 583.08
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(Rac)-Apremilast D5

(Rac)-Apremilast D5 ((Rac)-CC-10004 D5) is a deuterium labeled (R)-Apremilast. (R)-Apremilast ((R)-CC-10004) is a enantiomer of Apremilast[1].

  • CAS Number: 1258597-61-3
  • MF: C22H19D5N2O7S
  • MW: 465.53
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2,2′,4,5,5′-Pentachlorobiphenyl-3′,4′,6′-d3

2,2′,4,5,5′-Pentachlorobiphenyl-3′,4′,6′-d3 is the deuterium labeled 2,2′,4,5,5′-Pentachlorobiphenyl[1].

  • CAS Number: 1219794-68-9
  • MF: C12H2D3Cl5
  • MW: 329.45
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-Azido-L-phenylalanine hydrochloride

4-Azido-L-phenylalanine hydrochloride is an unnatural amino acid, which is used as an effective vibrational reporter of local protein environments.

  • CAS Number: 34670-43-4
  • MF: C9H11ClN4O2
  • MW: 242.662
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

ethyl 4,4,4-trimethylacetoacetate

Ethyl pivaloylacetate is a β-ketoester. Ethyl pivaloylacetate can be uesd as the substrate to evaluate the activity and stereoselectivity of the ketoreductase tool-box[1].

  • CAS Number: 17094-34-7
  • MF: C9H16O3
  • MW: 172.221
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 198.9±8.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 74.1±18.5 °C

2",4"-Di-O-(E-p-coumaroyl)afzelin

2'',4''-Di-O-(E-p-Coumaroyl)afzelin (compound 36) is a compound isolated from Epimedium sagittatum[1].

  • CAS Number: 163434-73-9
  • MF: C39H32O14
  • MW: 724.66
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 966.9±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 302.1±27.8 °C

23-Nor-6-oxopristimerol

23-Nor-6-oxopristimerol is a phenolic dinor-triterpene[1].

  • CAS Number: 118172-79-5
  • MF: C29H38O5
  • MW: 466.609
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 605.6±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 195.9±25.0 °C

(2-Chloro-7H-purin-6-yl)-furan-2-ylmethyl-amine

2-Chloro-N6-furfuryladenine is a Kinetin riboside derivative[1].

  • CAS Number: 101862-47-9
  • MF: C10H8ClN5O
  • MW: 249.66
  • Catalog: Cancer
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 499.4±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 255.8±28.7 °C