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50-21-5

50-21-5 structure
50-21-5 structure
  • Name: Lactic acid
  • Chemical Name: 2-hydroxypropanoic acid
  • CAS Number: 50-21-5
  • Molecular Formula: C3H6O3
  • Molecular Weight: 90.078
  • Catalog: API Synthetic anti-infective drugs Disinfectant antiseptic
  • Create Date: 2018-02-03 08:00:00
  • Modify Date: 2024-01-02 14:44:38
  • Lactate (Lactate acid) is the product of glycolysis. Lactate is produced by oxygen lack in contracting skeletal muscle in vivo, and can be removed under fully aerobic conditions. Lactate can be as a hemodynamic marker in the critically ill[1][2].
Name 2-hydroxypropanoic acid
Synonyms 2-Hydroxypropionic acid
EINECS 200-018-0
DL-Lactic acid
1H-Pyrrolo[2,3-b]pyridine-3-acetic acid, 5-bromo-a-oxo-
Lactic acid
MFCD00004520
Description Lactate (Lactate acid) is the product of glycolysis. Lactate is produced by oxygen lack in contracting skeletal muscle in vivo, and can be removed under fully aerobic conditions. Lactate can be as a hemodynamic marker in the critically ill[1][2].
Related Catalog
References

[1]. Brooks GA. Lactate: link between glycolytic and oxidative metabolism. Sports Med. 2007;37(4-5):341-3.

[2]. Fuller BM, et al. Lactate as a hemodynamic marker in the critically ill. Curr Opin Crit Care. 2012 Jun;18(3):267-72.
Density 1.3±0.1 g/cm3
Boiling Point 227.6±0.0 °C at 760 mmHg
Melting Point 18ºC
Molecular Formula C3H6O3
Molecular Weight 90.078
Flash Point 109.9±16.3 °C
Exact Mass 90.031693
PSA 57.53000
LogP -0.70
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.451

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OD2800000
CHEMICAL NAME :
Lactic acid
CAS REGISTRY NUMBER :
50-21-5
LAST UPDATED :
199712
DATA ITEMS CITED :
16
MOLECULAR FORMULA :
C3-H6-O3
MOLECULAR WEIGHT :
90.09
WISWESSER LINE NOTATION :
QY1&VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3543 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4875 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Rectal
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
1810 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - quail
DOSE/DURATION :
>2250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Rodent - hamster Ovary
DOSE/DURATION :
10 mmol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 240,195,1990 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80595 No. of Facilities: 10707 (estimated) No. of Industries: 56 No. of Occupations: 50 No. of Employees: 68982 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80595 No. of Facilities: 10134 (estimated) No. of Industries: 39 No. of Occupations: 58 No. of Employees: 107962 (estimated) No. of Female Employees: 63436 (estimated)
Symbol GHS05
GHS05
Signal Word Danger
Hazard Statements H315-H318
Precautionary Statements P280-P305 + P351 + P338
Personal Protective Equipment Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi: Irritant;C: Corrosive;
Risk Phrases R34;R38;R41
Safety Phrases 26-39-45-36/37/39
RIDADR UN 1760
WGK Germany 2
RTECS OD2800000
Packaging Group III
Hazard Class 8
HS Code 2918110000
81388-05-8 structure

81388-05-8

~%

50-21-5 structure

50-21-5

50-21-5 structure

50-21-5
Literature: Kozarich, John W.; Chari, Ravi V. J. Journal of the American Chemical Society, 1982 , vol. 104, # 9 p. 2655 - 2657
81388-02-5 structure

81388-02-5

~%

50-21-5 structure

50-21-5

50-21-5 structure

50-21-5
Literature: Kozarich, John W.; Chari, Ravi V. J. Journal of the American Chemical Society, 1982 , vol. 104, # 9 p. 2655 - 2657
113-24-6 structure

113-24-6

~%

50-21-5 structure

50-21-5

50-21-5 structure

50-21-5
Literature: Mandler, Daniel; Willner, Itamar Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1986 , p. 805 - 812
41656-56-8 structure

41656-56-8

~%

50-21-5 structure

50-21-5
Literature: Clelland, James D.; Thornalley, Paul J. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1991 , # 12 p. 3009 - 3016
HS Code 2918110000
Summary 2918110000. lactic acid, its salts and esters. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

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