148182-34-7

148182-34-7 structure

Name: tert-butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanyl-OH
Chemical Name: N-Boc-Phe-Leu-Phe-Leu-Phe
CAS Number: 148182-34-7
Molecular Formula: C₄₄H₅₉N₅O₈
Molecular Weight: 785.97
Catalog: Research Areas Neurological Disease
Create Date: 2019-06-30 15:47:15
Modify Date: 2024-01-09 11:15:09
N-Boc-Phe-Leu-Phe-Leu-Phe (Boc-FLFLF) is a formyl peptide receptor 1 (FPR1) antagonist, which increases pain effects and inhibits antinociceptive activity of annexin[1][2].

Name	N-Boc-Phe-Leu-Phe-Leu-Phe
Synonyms	MFCD00076350

Description	N-Boc-Phe-Leu-Phe-Leu-Phe (Boc-FLFLF) is a formyl peptide receptor 1 (FPR1) antagonist, which increases pain effects and inhibits antinociceptive activity of annexin[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
Target	FPR1[1]
References	[1]. Schepetkin IA, et al. Antagonism of human formyl peptide receptor 1 (FPR1) by chromones and related isoflavones. Biochem Pharmacol. 2014 Dec 15;92(4):627-41. [2]. Pei L, et al. Annexin 1 exerts anti-nociceptive effects after peripheral inflammatory pain through formyl-peptide-receptor-like 1 in rat dorsal root ganglion. Br J Anaesth. 2011 Dec;107(6):948-58.

Molecular Formula	C₄₄H₅₉N₅O₈
Molecular Weight	785.97