Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

DOPE

1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA[1].

  • CAS Number: 4004-05-1
  • MF: C41H78NO8P
  • MW: 744.034
  • Catalog: Inflammation/Immunology
  • Density: 1.008g/cm3
  • Boiling Point: 759.2±70.0 °C at 760 mmHg
  • Melting Point: 200 °C
  • Flash Point: 413.0±35.7 °C

(S)-N-Boc-4-Bromophenylalanine

Boc-Phe(4-Br)-OH is a phenylalanine derivative[1].

  • CAS Number: 62129-39-9
  • MF: C14H18BrNO4
  • MW: 344.201
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 475.3±40.0 °C at 760 mmHg
  • Melting Point: 118ºC
  • Flash Point: 241.2±27.3 °C

Rel-(3R,4R)-3-(5,6-Dihydro-4H-Pyrrolo[3,2,1-Ij]Quinolin-1-Yl)-4-(1H-Indol-3-Yl)-2,5-Pyrrolidinedione

(rel)-Tivantinib is a potent and highly selective inhibitor of the receptor tyrosine kinase c-MET. (rel)-Tivantinib has two novel targets, GSK3α and GSK3β, which play an important role in the cellular mechanism of non-small cell lung cancer (NSCLC)[1].

  • CAS Number: 905853-99-8
  • MF: C23H19N3O2
  • MW: 369.42
  • Catalog: Cancer
  • Density: 1.49±0.1 g/cm3(Predicted)
  • Boiling Point: 715.9±60.0 °C(Predicted)
  • Melting Point: N/A
  • Flash Point: 386.8±32.9 °C

Iodobenzene-d5

Iodobenzene-d5 is the deuterium labeled 1-Iodobenzene[1].

  • CAS Number: 7379-67-1
  • MF: C6D5I
  • MW: 209.03900
  • Catalog: Others
  • Density: 1.868 g/mL at 25ºC
  • Boiling Point: 188ºC(lit.)
  • Melting Point: -29ºC(lit.)
  • Flash Point: 74ºC

Shionone

Shionone is the major triterpenoid isolated from Aster tataricus, has anti-tussive, anti-inflammatory activities[1][2]. Shionone possesses a unique six-membered tetracyclic skeleton and 3-oxo-4-monomethyl structure[1].

  • CAS Number: 10376-48-4
  • MF: C30H50O
  • MW: 426.717
  • Catalog: Inflammation/Immunology
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 485.6±14.0 °C at 760 mmHg
  • Melting Point: 161-162°
  • Flash Point: 200.5±15.1 °C

BODIPY FL L-Cystine

BODIPY FL L-Cystine is a thiol-reactive, green-fluorescent dye. BODIPY FL L-Cystine can be the labeling of membrane proteins, proteins with hydrophobic binding sites, or hydrophobic ligands. (λex=504 nm, λem=511 nm)[1][2].

  • CAS Number: 1180490-57-6
  • MF: C34H38B2F4N6O6S2
  • MW: 788.45
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Novaluron

Novaluron is a chemical with pesticide properties, belonging to the class of insecticides called insect growth regulators.

  • CAS Number: 116714-46-6
  • MF: C17H9ClF8N2O4
  • MW: 492.70500
  • Catalog: Others
  • Density: 1.601 g/cm3
  • Boiling Point: N/A
  • Melting Point: 177.5ºC
  • Flash Point: N/A

Hydroxy ziprasidone

Hydroxy ziprasidone is an impurity of Ziprasidone[1]. Ziprasidone, an antipsychotic agent, is a combined 5-HT (serotonin) and dopamine receptor antagonist[2].

  • CAS Number: 884305-08-2
  • MF: C21H21ClN4O2S
  • MW: 428.93500
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(cis-1,4-Dihydroxycyclohexyl)acetic acid

Rengynic acid can be isolated from the seeds of Forsythia suspensa. Rengynic acid has potent antiviral effect on RSV[1].

  • CAS Number: 517883-38-4
  • MF: C8H14O4
  • MW: 174.19
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 385.9±27.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 201.4±20.2 °C

PhD

Thromboxane B2 is a prostaglandin derivative that is released during anaphylaxis. Thromboxane B2 induces arterial contraction and platelet aggregation.

  • CAS Number: 54397-85-2
  • MF: C20H34O6
  • MW: 370.480
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 582.5±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 199.7±23.6 °C

Probucol

Probucol is an anti-hyperlipidemic drug by lowering the level of cholesterol in the bloodstream by increasing the rate of LDL catabolism.Target: OthersProbucol is a drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. Probucol inhibited cholesterol efflux up to 80% in J774 macrophages expressing ABCA1. probucol is an effective inhibitor of ABCA1-mediated cholesterol efflux without influencing scavenger receptor class B type I-mediated efflux. The inhibition of ABCA1 translocation to the plasma membrane may in part explain the reported in vivo high-density lipoprotein-lowering action of probucol [1].

  • CAS Number: 23288-49-5
  • MF: C31H48O2S2
  • MW: 516.842
  • Catalog: Metabolic Disease
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 546.7±50.0 °C at 760 mmHg
  • Melting Point: 117 118ºC
  • Flash Point: 264.9±28.8 °C

(Aminomethyl)phosphonic acid-d2

(Aminomethyl)phosphonic acid-d2 is the deuterium labeled (Aminomethyl)phosphonic acid[1].

  • CAS Number: 30926-24-0
  • MF: CH4D2NO3P
  • MW: 113.05
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-Fluoro-2-nitrobenzene-13C6

1-Fluoro-2-nitrobenzene-13C6 is the 13C-labeled 1-Fluoro-2-nitrobenzene[1].

  • CAS Number: 2230123-14-3
  • MF: 13C6H4FNO2
  • MW: 147.06
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

CEP dipeptide 1

CEP dipeptide 1 is a CEP dipeptide with potent angiogenic activity; mediators of age-related macular degeneration (AMD).

  • CAS Number: 816432-15-2
  • MF: C18H27N3O6
  • MW: 381.42300
  • Catalog: Peptides
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-Asp(OtBu)-OH-13C4,15N

Fmoc-Asp(OtBu)-OH-13C4,15N is the 13C and 15N labeled Fmoc-Asp(OtBu)-OH[1]. Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis[2].

  • CAS Number: 1160760-08-6
  • MF: C1913C4H2515NO6
  • MW: 416.41
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3β-Hydroxytaraxast-20-en-16-one

3β-Hydroxytaraxast-20-en-16-one is a natural product isolated from eucalyptol/alcohol extract[1].

  • CAS Number: 42482-69-9
  • MF: C30H48O2
  • MW: 440.70092
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ammijin

Marmesinin ((-)-Marmesinin), a natural coumarin, is a biosynthetic precursor of psoralen and linear furanocoumarins. Marmesinin exhibits significant neuroprotective activities against glutamate-induced toxicity[1][2].

  • CAS Number: 495-30-7
  • MF: C20H24O9
  • MW: 408.39900
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boc-D-Orn(N3)-OH (CHA)

Boc-D-Orn(N3)-OH (CHA) is a click chemistry reagent containing an azide group.

  • CAS Number: 1858224-18-6
  • MF: C16H31N5O4
  • MW: 357.45
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

GPR35 agonist 1

GPR35 agonist 1 (compound 50) is a potent and specific G protein-coupled receptor-35 (GPR35) agonist with an EC50 of 5.8 nM, displays good druggability[1].

  • CAS Number: 2079880-92-3
  • MF: C10H4BrN5O5
  • MW: 354.07
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

10-Hydroxy majoroside

10-Hydroxy majoroside is a methanol extract isolated from plantago asiatica[1].

  • CAS Number: 259753-12-3
  • MF: C17H24O11
  • MW: 404.366
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

LC kinetic stabilizer-2

LC kinetic stabilizer-2 is a potent  amyloidogenic immunoglobulin light chain (LC) kinetic stabilizer with an EC50 of 24 nM[1].

  • CAS Number: 2495750-20-2
  • MF: C28H31N3O3
  • MW: 457.56
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Olgotrelvir

Olgotrelvir is an antiviral agent[1].

  • CAS Number: 2763596-71-8
  • MF: C22H30N4O7S
  • MW: 494.56
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Hydrocortisone Valerate

Hydrocortisone 17-valerate (Cortisol 17-valerate) is a thiazolidine compound[1].

  • CAS Number: 57524-89-7
  • MF: C26H38O6
  • MW: 446.57600
  • Catalog: Others
  • Density: 1.21g/cm3
  • Boiling Point: 595.1ºC at 760mmHg
  • Melting Point: 217-220 °C
  • Flash Point: 195ºC

Human enteropeptidase-IN-3

Human enteropeptidase-IN-3 is an enteropeptidase inhibitor. Human enteropeptidase-IN-3 exhibits enteropeptidase activity and long duration of inhibitory state. Human enteropeptidase-IN-3 can be used for intetinal digestive related diseases research[1].

  • CAS Number: 1958037-36-9
  • MF: C22H22N4O8
  • MW: 470.43
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

GSPT1 degrader-2

GSPT1 degrader-2 is a potent GSPT1 degrader[1].

  • CAS Number: 2803879-60-7
  • MF: C22H20ClN3O5
  • MW: 441.86
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Glycosolone

Glycosoloneis a alkaloidthat can be found in Glycosmis pentaphylla[1].

  • CAS Number: 67879-81-6
  • MF: C16H19NO3
  • MW: 273.33
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 410.2±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 201.9±28.7 °C

Licorice glycoside C2

Licorice glycoside C2 is a oleanane-type triterpene oligoglycoside isolated from Glycyrrhiza uralensis. Various biological activities are associated with licorice extracts, such as anti-viral, anti-microbial, antioxidant, anti-inflammatory, anti-ulcer, anti-cancer and anti-HIV effects[1].

  • CAS Number: 202657-55-4
  • MF: C36H38O16
  • MW: 726.68
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-Hydroxy-4',5-dimethoxystilbene

3-Hydroxy-4',5-dimethoxystilbene is a natural compound found in stem bark of Morus nigra L[1].

  • CAS Number: 58436-29-6
  • MF: C16H16O3
  • MW: 256.296
  • Catalog: Cancer
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 453.4±33.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 228.0±25.4 °C

1-(2H3)Methyl-2-azepanone

1-Methylazepan-2-one-d3 is the deuterium labeled 1-Methylazepan-2-one[1].

  • CAS Number: 203645-60-7
  • MF: C7H10D3NO
  • MW: 130.203
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 247.8±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 103.3±0.0 °C

UNII:TL35μ1249

1,1'-Binaphthyl-2,2'-diamine is the inactive isomer of (S)-[1,1'-Binaphthalene]-2,2'-diamine (HY-W007978A), and can be used as an experimental control. (S)-[1,1'-Binaphthalene]-2,2'-diamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 4488-22-6
  • MF: C20H16N2
  • MW: 284.35
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 480.8±30.0 °C at 760 mmHg
  • Melting Point: 242-244ºC(lit.)
  • Flash Point: 293.9±24.0 °C