1639303-73-3
1639303-73-3 structure
- Name: Odatroltide
- Chemical Name: Odatroltide
- CAS Number: 1639303-73-3
- Molecular Formula: C32H51N7O8
- Molecular Weight: 661.79
- Catalog: Research Areas Cardiovascular Disease
- Create Date: 2022-01-29 21:10:07
- Modify Date: 2024-01-09 13:47:06
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Odatroltide, as a nanoscale P-selectin inhibitor, is a nano-delivery system of 6,7-dihydroxyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid and KPAK to target the thrombus[1].
| Name | Odatroltide |
|---|
| Description | Odatroltide, as a nanoscale P-selectin inhibitor, is a nano-delivery system of 6,7-dihydroxyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid and KPAK to target the thrombus[1]. |
|---|---|
| Related Catalog | |
| Target |
P-selectin[1] |
| In Vitro | Odatroltide (1 nM) effectively down-regulates P-selectin expression. DHDMIQK(KAP) effectively inhibits platelet aggregation via down-regulating the expression of P-selectin. Odatroltide effectively inhibits platelet aggregations induced by TH, AA, ADP and PAF, which are correlated with the downregulation of P-selectin expression and with the scavenging of the free radicals[1]. |
| In Vivo | Odatroltide (0.01 nmol/kg) lyses the thrombus and inhibits thrombosis with a minimal[1]. |
| References |
| Molecular Formula | C32H51N7O8 |
|---|---|
| Molecular Weight | 661.79 |