Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

H-Ala-OiPr

L-Alanine isopropyl ester is an alanine derivative[1].

  • CAS Number: 39825-33-7
  • MF: C6H14ClNO2
  • MW: 167.634
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 191.4ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 69.5ºC

Isocarapanaubine

7-Isocarapanaubine is an indole that can be isolated from Rauwolfi vomitoria[1].

  • CAS Number: 17391-09-2
  • MF: C23H28N2O6
  • MW: 428.478
  • Catalog: Cancer
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 599.5±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 316.4±30.1 °C

3-(Bromomethyl)benzonitrile-d6

3-(Bromomethyl)benzonitrile-d6 is the deuterium labeled 3-(Bromomethyl)benzonitrile[1].

  • CAS Number: 1219802-21-7
  • MF: C8H6BrN
  • MW: 196.044
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 271.5±15.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 118.0±20.4 °C

Tectoruside

Tectoruside is a phenol acid glycoside of the rhizome of Iris dichotoma Pall. Iris dichotoma Pall, a traditional Chinese herbal medicine, has been used in several disorders such as inflammation, throat disorders, asthma and coughs[1].

  • CAS Number: 38784-73-5
  • MF: C21H30O13
  • MW: 490.46
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Isovitexin-2''-O-rhamnoside (2''-O-alpha-L-Rhamnopyranosyl-isovitexin)

Isovitexin 2′′-O-rhamnoside, a phenolic, has antioxidant and antiproliferative activities[1].

  • CAS Number: 72036-50-1
  • MF: C27H30O14
  • MW: 578.52
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 225-230 °C
  • Flash Point: N/A

19-Hydroxy-10-deacetylbaccatin III

19-Hydroxy-10-deacetylbaccatin III (compound 13) is a taxane with potential antitumor activity. 19-Hydroxy-10-deacetylbaccatin III has weak cytotoxicity against A498 and NCI-H226 cell lines. The study found that the inhibition rates of 30 μg/mL 19-Hydroxy-10-deacetylbaccatin III on A498, NCI-H226 and PC-3 were 16.6% and 32% respectively[1].

  • CAS Number: 154083-99-5
  • MF: C29H36O11
  • MW: 560.59
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(3β,9β,23E)-9,19-Cyclolanost-23-ene-3,25-diol

Cycloart-23-ene-3β,25-diol is a natural crystalline triterpene[1].

  • CAS Number: 14599-48-5
  • MF: C30H50O2
  • MW: 442.717
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 536.1±23.0 °C at 760 mmHg
  • Melting Point: 198-199℃
  • Flash Point: 218.1±17.2 °C

(Z)-p-cyano-α-Cyanostilbene

(Z)-p-cyano-α-Cyanostilbene (compound 11), a phenantrene derivative, has antiproliferative activity. (Z)-p-cyano-α-Cyanostilbene shows significant selectivity against HeLa (IC50=0.21 µM) and HepG2 (IC50=0.230 µM) cells without cytotoxic against normal skin fibroblasts (IC50>100 µM)[1].

  • CAS Number: 54676-54-9
  • MF: C16H10N2
  • MW: 230.26
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

ODN 1982

ODN 1982 is a unmethylated CpG oligodeoxyribonucleotide (ODN), can be used to prepare DNA vaccines. ODN 1982 inhibits R-848 signaling. ODN 1982 sequence: 5’-tccaggacttctctcaggtt-3’[1][2].

  • CAS Number: 207623-15-2
  • MF:
  • MW:
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[PDP(polyethylene glycol)-2000] (aMMoniuM salt)

DSPE-PEG-PDP is a phospholipid PEG conjugate that can be used in drug delivery applications[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Z-Val-OSu

Z-Val-Osu is a valine derivative[1].

  • CAS Number: 3496-11-5
  • MF: C17H20N2O6
  • MW: 348.350
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: 106-120ºC
  • Flash Point: N/A

Neuraminidase

Neuraminidase (Exo-α-sialidase) is an exosialidase, is often used in biochemical studies. Neuraminidase cleaves α-ketosidic linkage between the sialic (N-acetylneuraminic) acid and an adjacent sugar residue. Neuraminidase, derived from mucosal pathogens, is a virulence factor that modifies the host's response to infection[1].

  • CAS Number: 9001-67-6
  • MF: C9H14N4O3
  • MW: 226.232
  • Catalog: Infection
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 656.2±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 350.7±31.5 °C

HPV16 E7 86-93

HPV16 E7 (86-93) HLA-A2-restricted HPV type 16 E7 peptide[1].

  • CAS Number: 160212-93-1
  • MF: C37H66N8O10S
  • MW: 815.03
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Nalpha-[(9H-Fluoren-9-ylmethoxy)carbonyl]-Nepsilon-tetradecanoyl-L-lysine

Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-Nε-tetradecanoyl-L-lysine is a lysine derivative[1].

  • CAS Number: 1128181-23-6
  • MF: C35H50N2O5
  • MW: 578.782
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 780.6±60.0 °C at 760 mmHg
  • Melting Point: 140 °C
  • Flash Point: 425.9±32.9 °C

Schineolignin C

Schineolignin C is a Lignan that can be isolated from the fruit of schisandra chinensis. schisandra chinensis has antihepatitis, antitumor, and anti-HIV-1 activities[1].

  • CAS Number: 1352185-28-4
  • MF: C21H28O5
  • MW: 360.44
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Amino(3-thienyl)acetic acid

(R)-2-Amino-2-(thiophen-3-yl)acetic acid is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 1194-86-1
  • MF: C6H7NO2S
  • MW: 157.190
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 383.8±22.0 °C at 760 mmHg
  • Melting Point: 218℃
  • Flash Point: 185.9±22.3 °C

H-Cys-OEt.HCl

L-Cysteine ethyl ester HCl is a cysteine derivative[1].

  • CAS Number: 868-59-7
  • MF: C5H12ClNO2S
  • MW: 185.672
  • Catalog: Others
  • Density: 1.391 g/cm3
  • Boiling Point: 205.9ºC at 760 mmHg
  • Melting Point: 123-125 °C(lit.)
  • Flash Point: 78.3ºC

Fmoc-Thr(Bzl)-OH

Fmoc-Thr(Bzl)-OH is a threonine derivative[1].

  • CAS Number: 117872-75-0
  • MF: C26H25NO5
  • MW: 431.480
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 643.7±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 343.1±31.5 °C

Fmoc-Asp(OtBu)-Thr(psi(Me,Me)pro)-OH

Fmoc-Asp(OtBu)-Thr(psi(Me,Me)pro)-OH is a dipeptide.

  • CAS Number: 920519-32-0
  • MF: C30H36N2O8
  • MW: 552.61500
  • Catalog: Others
  • Density: 1.240±0.06 g/cm3 (20 °C, 760 mmHg)
  • Boiling Point: 753.3±60.0 °C (760 mmHg)
  • Melting Point: N/A
  • Flash Point: N/A

dl-beta-homomethionine

DL-β-Homomethionine is a Methionine (HY-13694) derivative[1].

  • CAS Number: 158570-14-0
  • MF: C6H13NO2S
  • MW: 163.23800
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 190-193ºC (dec.)
  • Flash Point: N/A

IlexgeninA

Ilexgenin A is a pentacyclic triterpenoid, which extracted from Ilex hainanensis Merr. Ilexgenin A can be used for the research of inflammation and cancer[1].

  • CAS Number: 108524-94-3
  • MF: C30H46O6
  • MW: 502.683
  • Catalog: Cancer
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 653.3±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 362.9±28.0 °C

NLS PKKKRKV

NLS (PKKKRKV) is a peptide derived from the simian virus 40 large tumor antigen (SV40 large T antigen), as a method to enhance nuclear entry in the field of gene transfer research[1][2].

  • CAS Number: 95088-49-6
  • MF: C40H78N14O8
  • MW: 883.14
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

A12-Iso5-4DC19

A12-Iso5-4DC19 is a linked lipid and exhibits anti-tumor immunity. A12-Iso5-4DC19 can facilitate mRNA delivery and be used for the research of RNA vaccines[1].

  • CAS Number: 2412492-20-5
  • MF: C47H85N3O2
  • MW: 724.20
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-His-Phe-OH

H-His-Phe-OH is adipeptide.

  • CAS Number: 16874-81-0
  • MF: C15H18N4O3
  • MW: 302.33
  • Catalog: Others
  • Density: 1.34 g/cm3
  • Boiling Point: 693.4ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 373.1ºC

Stigmastane-3,6-diol

6α-Hydroxysitostanol is a marker of sitostanol oxidation[1].

  • CAS Number: 112244-29-8
  • MF: C29H52O2
  • MW: 432.72
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 523.8±33.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 211.4±20.0 °C

1-Heptadecanoyl-2-palmitoleoyl-sn-glycero-3-phospho- L-serine-d5 sodium

1-Heptadecanoyl-2-palmitoleoyl-sn-glycero-3-phospho- L-serine-d5 (sodium) is deuterium labeled 1-Heptadecanoyl-2-palmitoleoyl-sn-glycero-3-phospho- L-serine (sodium).

  • CAS Number: 2342575-67-9
  • MF: C39H69D5NNaO10P
  • MW: 776.00
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Harmalane

Harmalan (compound 8) is a alkaloid isolated from the extracts of the leaves of Flindersia laevicarpa[1].

  • CAS Number: 525-41-7
  • MF: C12H12N2
  • MW: 184.24
  • Catalog: Others
  • Density: 1.23g/cm3
  • Boiling Point: 390.3ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 189.9ºC

DUPA(OtBu)-OH

DUPA(OtBu)-OH is a DUPA precursor. DUPA is used as the targeting moiety to actively deliver Docetaxel (DTX) for treatment of Prostate-Specific Membrane Antigen (PSMA) expressing prostate cancer.

  • CAS Number: 1026987-94-9
  • MF: C23H40N2O9
  • MW: 488.57
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BAY-069

BAY-069 is a potent branched-chain amino acid transaminases 1 (BCAT1) and BCAT2 inhibitor with IC50 values of 31 nM and 153 nM, respectively. BAY-069 also can be used as a chemical probe. BAY-069 can be used tor research anticancer[1].

  • CAS Number: 2639638-66-5
  • MF: C22H14ClF3N2O3
  • MW: 446.81
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-Ethyl-N-nitroso-1-propanamine-d4

N-Ethyl-N-nitroso-1-propanamine-d4 is the deuterium labeled N-Ethyl-N-nitroso-1-propanamine[1].

  • CAS Number: 2733722-83-1
  • MF: C5H8D4N2O
  • MW: 120.19
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A