396716-14-6

396716-14-6 structure

Name: DABCYL-TNF-α-EDANS (-4 to +6) (human) trifluoroacetate salt
Chemical Name: DABCYL-TNF-α-EDANS (-4 to +6) (human)
CAS Number: 396716-14-6
Molecular Formula: C₇₀H₁₀₄N₂₂O₁₈S
Molecular Weight: 1573.776
Catalog: Research Areas Cancer
Create Date: 2018-06-25 20:14:33
Modify Date: 2024-01-12 17:19:21
DABCYL-TNF-α-EDANS (-4 to +6) (human) is a FRET peptide substrate of tumor necrosis factor convertase (TACE)[1].

Name	DABCYL-TNF-α-EDANS (-4 to +6) (human)
Synonyms	3,6,9,12,15,18,21-Heptaazahexacosa-3,6,9,12,15,18,21-heptaene-1,26-diimidic acid, 2,14-bis[3-[(aminoiminomethyl)amino]propyl]-23-[[(2S)-2-[[(2S)-2-[[4-[(E)-2-[4-(dimethylamino)phenyl]diazenyl]benzoyl] ;amino]-1-hydroxy-4-methylpentylidene]amino]-1-hydroxypropylidene]amino]-4,7,10,13,16,19,22-heptahydroxy-5,8,11-tris(hydroxymethyl)-20-methyl-17-(1-methylethyl)-N-[2-[(5-sulfo-1-naphthalenyl)amino]e thyl]-, (2S,5S,8S,11S,14S,17S,20S,23S)- (2S,5S,8S,11S,14S,17S,20S,23S)-2,14-Bis(3-carbamimidamidopropyl)-23-{[(2S)-2-({(2S)-2-[(4-{(E)-[4-(dimethylamino)phenyl]diazenyl}benzoyl)amino]-1-hydroxy-4-methylpentylidene}amino)-1-hydroxypropyliden ;e]amino}-4,7,10,13,16,19,22-heptahydroxy-5,8,11-tris(hydroxymethyl)-17-isopropyl-20-methyl-N-{2-[(5-sulfo-1-naphthyl)amino]ethyl}-3,6,9,12,15,18,21-heptaazahexacosa-3,6,9,12,15,18,21-heptaene-1,26- ;diimidic acid DABCYL-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Ser-Arg-EDANS TACE FRET Substrate I

Description	DABCYL-TNF-α-EDANS (-4 to +6) (human) is a FRET peptide substrate of tumor necrosis factor convertase (TACE)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Liepinsh E, et al. NMR structure of the netrin-like domain (NTR) of human type I procollagen C-proteinase enhancer defines structural consensus of NTR domains and assesses potential proteinase inhibitory activity and ligand binding. J Biol Chem. 2003 Jul 11;278(28):25982-9.