954134-42-0

954134-42-0 structure
954134-42-0 structure
  • Name: D-JBD19
  • Chemical Name: D-JBD19
  • CAS Number: 954134-42-0
  • Molecular Formula: C99H164N32O28
  • Molecular Weight: 2250.56
  • Catalog: Research Areas Neurological Disease
  • Create Date: 2020-06-01 11:38:22
  • Modify Date: 2025-08-26 12:34:12
  • D-JBD19 is a non-permeable peptide[1]. D-JBD19 has neuroprotective effects[2].

Name D-JBD19
Description D-JBD19 is a non-permeable peptide[1]. D-JBD19 has neuroprotective effects[2].
Related Catalog
In Vitro D-JBD19 is a non-permeable cargo corresponding to dJNKi peptide[1].
In Vivo Neuroprotective effects of D-JBD19 against middle cerebral artery occlusion (MCAO) as compared with D-JNKI1. 15.7 ng of either D-JBD19 or D-JNKI1 or 1570 ng of D-JBD19 are injected i.c.v. just after the ischemia. Animals were killed 24 h later. 100 times more D-JBD19 is needed to provide protection than with D-JNKI1[2].
References

[1]. Cardozo AK, et al. Cell-permeable peptides induce dose- and length-dependent cytotoxic effects. Biochim Biophys Acta. 2007 Sep;1768(9):2222-34.

[2]. Vaslin A, et al. Excitotoxicity-induced endocytosis mediates neuroprotection by TAT-peptide-linked JNK inhibitor. J Neurochem. 2011 Dec;119(6):1243-52.

Molecular Formula C99H164N32O28
Molecular Weight 2250.56
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