Promestriene

Modify Date: 2024-01-08 15:15:26

Promestriene structure	Common Name	Promestriene
	CAS Number	39219-28-8	Molecular Weight	328.488
	Density	1.1±0.1 g/cm3	Boiling Point	436.8±45.0 °C at 760 mmHg
	Molecular Formula	C₂₂H₃₂O₂	Melting Point	64-660ºC
	MSDS	N/A	Flash Point	153.3±28.3 °C

Use of Promestriene

Promestriene is a synthetic diethyl-ether of estradiol and a locally effective estrogen. Promestriene has an efficient action on vaginal atrophy while it is minimally absorbed[1][2].

Name	Promestriene
Synonym	More Synonyms

Description	Promestriene is a synthetic diethyl-ether of estradiol and a locally effective estrogen. Promestriene has an efficient action on vaginal atrophy while it is minimally absorbed[1][2].
Related Catalog	Research Areas >> Cancer Research Areas >> Endocrinology Signaling Pathways >> Others >> Others
In Vitro	Promestriene is an analogue of oestradiol which is minimally absorbed and devoid of systemic effects when administered intravaginally, either as gynecological cream or capsules[2]. Topical Promestriene is minimally absorbed with chronic use and has been reported to significantly improve the symptoms of vaginal atrophy[3].
References	[1]. Isabel Santos, et al. Urogenital Disorders Associated With Oestrogen Deficiency: The Role of Promestriene as Topical Oestrogen Therapy. Gynecol Endocrinol. 2010 Sep;26(9):644-51. [2]. Lino Del Pup, et al. Promestriene, a Specific Topic Estrogen. Review of 40 Years of Vaginal Atrophy Treatment: Is It Safe Even in Cancer Patients. Anticancer Drugs. 2013 Nov;24(10):989-98. [3]. AJO Almodovar, et al. Abstract P5-05-07: Promestriene effects on estrogen-sensitive breast cancer cell proliferation in vitro. Cancer Res 2013;73(24 Suppl): Abstract nr P5-05-07.

Density	1.1±0.1 g/cm3
Boiling Point	436.8±45.0 °C at 760 mmHg
Melting Point	64-660ºC
Molecular Formula	C₂₂H₃₂O₂
Molecular Weight	328.488
Flash Point	153.3±28.3 °C
Exact Mass	328.240234
PSA	18.46000
LogP	6.48
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.546
Storage condition	-20°C Freezer

17-Methoxy-3-propoxyestra-1,3,5(10)-triene

MFCD00867247

Promestriene

EINECS 254-361-6

Promestriene [DCF:INN]

Estra-1,3,5(10)-triene, 17-methoxy-3-propoxy-

3-Propoxy-17beta-methoxy-1,3,5(10)-estratriene

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Promestriene
Price: ￥748.0/250mg ￥218.0/50mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Promestriene
Price: $200.0/100mg $400.0/250mg $800.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 3-Propoxy-17beta-methoxy-1,3,5(10)-estratriene
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: Promestriene
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Promestriene API
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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Price: ￥224/100mg

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Promestriene

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