Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

(2E,4E)-Deca-2,4-dienal

trans,trans-2,4-Decadienal is a lipid peroxidation product of linolieic acid[1].

  • CAS Number: 25152-84-5
  • MF: C10H16O
  • MW: 152.233
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 244.6±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 102.3±11.0 °C

15:0 Lyso PE-d5

15:0 Lyso PE-d5 is deuterium labeled 15:0 Lyso PE.

  • CAS Number: 2342574-96-1
  • MF: C20H37D5NO7P
  • MW: 444.55
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

acid blue 92

Anazolene trisodium is an anionic dye, a textile azo dye with a maximum absorption wavelength of λmax = 571 nm[1][2].

  • CAS Number: 3861-73-2
  • MF: C26H16N3Na3O10S3
  • MW: 695.584
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: >300°C
  • Flash Point: N/A

6-Thioinosine Phosphate

6-Thioinosine Phosphate (Thioinosinic acid) is an intermediate metabolite of azathioprine (HY-B0256). Azathioprine is a purine analog immunosuppressive drug[1].

  • CAS Number: 53-83-8
  • MF: C10H13N4O7PS
  • MW: 364.27
  • Catalog: Inflammation/Immunology
  • Density: 2.25g/cm3
  • Boiling Point: 833.4ºC at 760mmHg
  • Melting Point: 149-155ºC (dec.)
  • Flash Point: 457.9ºC

Acenaphthylene

Acenaphthylene is a polycyclic aromatic hydrocarbon (PAH). PAHs are derived naturally from coal and tar deposits, and produced by incomplete combustion of organic matter[1].

  • CAS Number: 208-96-8
  • MF: C12H8
  • MW: 152.192
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 298.9±7.0 °C at 760 mmHg
  • Melting Point: 78-82 °C(lit.)
  • Flash Point: 137.2±8.9 °C

Sodium tauroglycocholate

Sodium tauroglycocholate is an inhibitor of the biliary acid transporting system of the hepatocyte and also a surfactant used as a chemical permeation enhancer.

  • CAS Number: 41945-48-6
  • MF: C28H47N2NaO8S
  • MW: 594.736
  • Catalog: Endocrinology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

F(N-Me)GA(N-Me)IL

F(N-Me)GA(N-Me)IL is a biological active peptide. (Double N-methylated derivatives of amyloidogenic and cytotoxic partial IAPP sequence were found to be devoid of β-sheet structure, amyloidogenicity and cytotoxicity, The derivatives were able to interact with the native sequences and inhibit amyloid formation)

  • CAS Number: 409085-40-1
  • MF: C28H45N5O6
  • MW: 547.69
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Methylophiopogonone B

Methylophiopogonone B, a homoisoflavonoidal compound that could be isolated from Ophiopogonis Tiber, could scavenge •OH and H2O2 in vitro to a certain extent[1][2].

  • CAS Number: 74805-89-3
  • MF: C19H18O5
  • MW: 326.343
  • Catalog: Metabolic Disease
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 547.7±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 199.7±23.6 °C

2,4-Difluorophenylethynylcobalamin

2,4-Difluorophenylethynylcobalamin is a potential B12 antivitamin via binding to human B12 -processing enzyme CblC with high affinity (KD=130 nm). 2,4-Difluorophenylethynylcobalamin withstood tailoring by CblC, and stabilizes the ternary complex with the cosubstrate glutathione (GSH)[1].

  • CAS Number: 2101750-19-8
  • MF: C70H91CoF2N13O14P
  • MW: 1466.45
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Gly-Leu-OH

Glycyl-l-leucine is a dipeptide that can be a common substrate for glycyl-leucine dipeptidase.

  • CAS Number: 869-19-2
  • MF: C8H16N2O3
  • MW: 188.224
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 410.4±30.0 °C at 760 mmHg
  • Melting Point: 233-235 °C(lit.)
  • Flash Point: 202.0±24.6 °C

NSC16168

NSC16168 is a specific inhibitor of ERCC1-XPF, with an IC50 value of 0.42 μM. NSC16168 inhibits DNA repair and potentiates CDDP efficacy in cancer[1].

  • CAS Number: 6837-93-0
  • MF: C17H15NO9S3
  • MW: 473.49700
  • Catalog: Cancer
  • Density: 1.683g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(S)-15-Deoxyspergualin

(-)-15-Deoxyspergualin is a potent antitumor agent. (-)-15-Deoxyspergualin shows strong inhibition against mouse leukemia L-1210[1].

  • CAS Number: 89149-10-0
  • MF: C17H37N7O3
  • MW: 387.52100
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Miltipolone

Miltipolone is a potent cytotoxic compound isolated from the fresh roots of Salvia divinorum[1].

  • CAS Number: 131086-61-8
  • MF: C19H24O3
  • MW: 300.39200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Imisopasem manganese

Imisopasem manganese (M40403) is a stable non-peptidyl mimetic of manganese superoxide MnSOD.

  • CAS Number: 218791-21-0
  • MF: C21H35Cl2Mn2N5-
  • MW: 538.32
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ethyl coumarin-3-carbaoxylate

Ethyl 3-coumarincarboxylate is a coumarin derivative. Ethyl 3-coumarincarboxylate can be used as a pseudo-template to give a molecularly imprinted polymer (MIP) that has a fairly specific recognition capability for aflatoxins[1].

  • CAS Number: 1846-76-0
  • MF: C12H10O4
  • MW: 218.205
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 378.0±30.0 °C at 760 mmHg
  • Melting Point: 92-94 °C(lit.)
  • Flash Point: 195.6±23.0 °C

Alboctalol

Alboctalol can be isolated from Morus australis. Alboctalol has weak cytotoxicity against P-388 cells[1].

  • CAS Number: 62394-00-7
  • MF: C28H24O8
  • MW: 488.485
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 779.0±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 345.1±27.5 °C

Bacopasaponin C

Bacopasaponin C is an indigenous glycoside isolated from Bacopa monniera, with antitumor and anti-leishmanial activities[1][2].

  • CAS Number: 178064-13-6
  • MF: C46H74O17
  • MW: 899.070
  • Catalog: Cancer
  • Density: 1.4±0.0 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Thymopoietin II: 32-35

Thymocartin (Thymopoietin II (32-35)) is the 32-35 fragment of the thymic factor (thymopoietin). Thymocartin has shown potential for immunodeficiency diseases research[1][2].

  • CAS Number: 85466-18-8
  • MF: C21H40N8O7
  • MW: 516.59200
  • Catalog: Inflammation/Immunology
  • Density: 1.45g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

AEZS-108

Zoptarelin doxorubicin (AEZS-108; AN-152) is a hybrid anticancer agent, containing Zoptarelin and Doxorubicin. Zoptarelin doxorubicin has been used to research targeting tumors expressing LHRH receptors. Zoptarelin doxorubicin abolishes tumor progression and induces remarkable apoptosis in vitro[1].

  • CAS Number: 139570-93-7
  • MF: C91H117N19O26
  • MW: 1893.014
  • Catalog: Cancer
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2-Acetyl-3,5-dihydroxyphenylacetic acid

Curvulinic acid is a phytotoxic compound, has herbicidal activity[1].

  • CAS Number: 19053-94-2
  • MF: C10H10O5
  • MW: 210.18300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-C-Carboxy-2-deoxypentaric acid

Hydroxycitric acid is a natural antiobesity agent, that can be isolated from the fruits of Garcinia gummi-gutta (L.) Roxb[1].

  • CAS Number: 6205-14-7
  • MF: C6H8O8
  • MW: 208.12
  • Catalog: Metabolic Disease
  • Density: 1.9±0.1 g/cm3
  • Boiling Point: 393.3±42.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 205.8±24.4 °C

Fasedienol

Fasedienol is a neurochemical stimulator of the vomeronasal organ (VON). Fasedienol alleviates the symptoms of PMS and anxiety (extracted from patent WO1998014194A1)[1].

  • CAS Number: 23062-06-8
  • MF: C19H28O
  • MW: 272.42500
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Bentazon

Bentazone is a post-emergence herbicide used for selective control of broadleaf weeds and sedges in beans, rice, corn, peanuts, mint and others. It acts by interfering with photosynthesis[1].

  • CAS Number: 25057-89-0
  • MF: C10H12N2O3S
  • MW: 240.279
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 395.7±25.0 °C at 760 mmHg
  • Melting Point: 137-139°C
  • Flash Point: 193.1±23.2 °C

Entadamide A 2'-O-(6''-O-β-D-glucopyranosyl)-β-D-glucopyranoside

Entadamide A 2'-O-(6''-O-β-D-glucopyranosyl)-β-D-glucopyranoside (MFLNH I) (compound 5) can be isolated from the seed kernel of Entada rheedei. Entada rheedei is a medicinal plant from Thailand that is used to suppress stomach pain[1].

  • CAS Number: 1427191-48-7
  • MF: C18H31NO12S
  • MW: 485.5
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Soybean phospholipid

Lecithin is regarded as a safe, conventional phospholipid source. Phospholipids are reported to alter the fatty acid composition and microstructure of the membranes in animal cells.

  • CAS Number: 8002-43-5
  • MF: C42H80NO8P
  • MW: 758.060
  • Catalog: Others
  • Density: 1.0305 g/cm3 (20ºC)
  • Boiling Point: N/A
  • Melting Point: 236.1ºC
  • Flash Point: 57 °C

Licoricesaponin A3

Licoricesaponin A3 is a terpenoid saponin identified from licorice[1].

  • CAS Number: 118325-22-7
  • MF: C48H72O21
  • MW: 985.07300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

dioctadecylamidoglycylspermine

Transfectam is a cationic lipid able to interact with DNA to form complexes that mediate efficient gene transfer into various eukaryotic cells[1].

  • CAS Number: 124050-77-7
  • MF: C49H102N6O2
  • MW: 807.373
  • Catalog: Metabolic Disease
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 840.6±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 462.2±34.3 °C

Kielcorin

Kielcorin is a xanthonethat can be found in Kielmeyera variabilis[1].

  • CAS Number: 64280-48-4
  • MF: C24H20O8
  • MW: 436.41
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

17:0-20:3 PC-d5

17:0-20:3 PC-d5 is deuterium labeled 17:0-20:3 PC.

  • CAS Number: 2342575-54-4
  • MF: C45H79D5NO8P
  • MW: 803.15
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(3β,5α,6β)-Stigmastane-3,5,6-triol

Sitostanetriol (Sitostane-3β,5α,6β-triol) is a steroid isolated from Casearia membranacea (Flacourtiaceae)[1].

  • CAS Number: 20835-91-0
  • MF: C29H52O3
  • MW: 448.721
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 535.6±40.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 216.2±21.9 °C