Top Suppliers:I want be here



72957-38-1

72957-38-1 structure
72957-38-1 structure
  • Name: Dynorphin A (1-13)
  • Chemical Name: Dynorphin A (1-13)
  • CAS Number: 72957-38-1
  • Molecular Formula: C75H126N24O15
  • Molecular Weight: 1603.955
  • Catalog: Biochemical Peptide
  • Create Date: 2018-09-14 12:55:00
  • Modify Date: 2024-01-02 18:27:25
  • Porcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations. Sequence: Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys.

Name Dynorphin A (1-13)
Synonyms UNII:VFC23V742Z
dynorphin A-(1-13)
DYNORPHIN 1-13
DYNORPHIN A (1-13),PORCINE
dyn A-(1-13)-OH
L-Tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-prolyl-L-lysyl-L-leucyl-L-lysine
DYNORPHIN A(HUMAN,1-13)
YGGFLRRIRPKLK
L-Lysine, L-tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-prolyl-L-lysyl-L-leucyl-
Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys
Dyn(1-13)
DYNORPHIN A PORCINE FRAGMENT 1-13
Dynorphin A (1-13) Acetate
Porcine dynorphin A(1-13)
Description Porcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations. Sequence: Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys.
Related Catalog
Target

Κ opioid receptor[1].

In Vivo Dynorphin A (1-13) exposure (33 μM) causes a significant loss in neuronal viability at 4 h with a visible destruction in neuronal morphology seen at 16 h. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+]i in individual neurons similar to increases seen with acute NMDA treatment. Continuous exposure to dynorphin A (1-13) (100 μM) causes a significant loss of neurons over time[1].
References

[1]. Hauser KF, et al. Dynorphin A (1-13) neurotoxicity in vitro: opioid and non-opioid mechanisms in mouse spinal cord neurons. Exp Neurol. 1999 Dec;160(2):361-75.

Density 1.4±0.1 g/cm3
Molecular Formula C75H126N24O15
Molecular Weight 1603.955
Exact Mass 1602.983398
PSA 661.70000
LogP -0.50
Index of Refraction 1.645
Storage condition -20°C
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3
Precursor  1

DownStream  0