L-Isoserine is a serine derivative[1].
Anticancer agent 149 (compound 3) is an anticancer agent isolated from the rhizome of Dioscorea dioscorea (DM). Anticancer agent 149 exhibits selective cytotoxic activity against MCF-7 cells (IC50=31.41 μM)[1].
GT-1 (LCB10-0200), a siderophore-linked cephalosporin, is effective against clinical isolates of P. aeruginosa, Klebsiella oxytoca, Proteus spp., Serratia marcescens, and Enterobacter aerogenes.
Clothianidin-2-S-propanoic acid is a clothianidin hapten. Clothianidin-2-S-propanoic can be used for the research of insecticide[1].
Dapagliflozin impurity A (Compound A) is a dapagliflozin peroxide, a genotoxic impurity, can cause damage to human genetic material at very low concentrations, leading to genetic mutations and possibly tumorigenesis[1].
2,4,6-Tribromo-3-methylphenol is an active compound[1].
5,5'-Dinitro BAPTA AM is a membrane-permeant, high-affinity calcium chelator, it can be used for investigation of the role of cytosolic Ca2+. 5,5'-Dinitro BAPTA AM can be loaded by incubation into live cells, and is cleaved by cytosolic esterases to liberate the active tetra-carboxylate ligand[1].
Clemaphenol A is a chemical constituent of the flower of Fritillaria pallidiflora[1].
Acetylleucine is a drug used in the treatment of vertigo.
Ala-Gly-Tyr is a tripeptide composed of L-alanine, glycine, and L-tyrosine joined in sequence by peptide linkages. Ala-Gly-Tyr has a role as a metabolite. Ala-Gly-Tyr is functionally related to L-alanine, glycine and L-tyrosine.
6''-O-trans-Feruloylcatalpol is a natural iridoid glycoside compound[1].
Auriculin A is a synthetic atrial natriuretic factor (ANF) with hemodynamic effect. Auriculin A antagonizes renal vasoconstriction in the dog, and influences on arterial baroreflex control of heart rate, systemic blood pressure, and perfusion pressure in the hind limb (perfused at constant flow) in rabbits[1][2].
1-Pyrenamin-d9 is the deuterium labeled 1-Pyrenamin[1].
CEF4 is a peptide that corresponds to aa 342-351 of the influenza A virus nucleocapsid protein.
N-Acetyl-S-benzyl-DL-cysteine is a cysteine derivative[1].
1,2,3,5-Tetramethylbenzene-d14 is the deuterium labeled 1,2,3,5-Tetramethylbenzene[1].
((4-(tert-Butyl)phenyl)sulfonyl)alanine is an alanine derivative[1].
Flucloronide (Fluclorolone acetonide) is a corticosteroid for topical, and has anti-inflammatory activity[1].
2,6-Difluoro-DL-phenylalanine is a phenylalanine derivative[1].
Epigomisin O is isolate from the fruits of Schisandra plants[1].
Zolimomab aritox (H65-RTA) is an immunocoupling compound consisting of a ricin (RTA) chain, a ribosomal inhibitory protein, coupled to a monoclonal antibody (H65) against the pan-T-cell antigen CD5. Zolimomab aritox has anticancer activity and can be used in cutaneous T-cell lymphoma studies[1].
Prohexadione (BX-112 free acid) is a plant growth regulator. Prohexadione inhibits gibberellin biosynthesis of plants[1][2].
Cytidoline sodium salt is an intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes and also exerts neuroprotective effects.
Hydrazine-d6 (sulfate) is the deuterium labeled Hydrazine sulfate[1].
Dehydroeburicoic acid monoacetate (Compound 18) is a lanostane triterpenoid isolated from Wolfiporia cocos[1].
AQ-13 dihydrochloride is an aminoquinoline antimalarial drug that is effective against chloroquine-resistant strains of Plasmodium falciparum.
BCECF-AM is a cell membrane permeable compound, widely used as a fluorescent indicator for intracellular pH.
(2S)-7,4'-Dihydroxy-3'-prenylflavan is a natural product[1].
(1R)-IDH889 is the inactive isomer of IDH889 (HY-112289), and can be used as an experimental control. IDH889 is an orally available, brain penetrant, allosteric and mutant specific inhibitor of isocitrate dehydrogenase 1 (IDH1). IDH889 has potent selectivity for IDH1 R132* mutations, with IC50s of 0.02 μM, 0.072 μM and 1.38 μM for IDH1R132H, IDH1R132C and IDH1wt, respectively. IDH889 shows potent cellular inhibition of R-2-hydroxyglutarate (2-HG) production with an IC50 of 0.014 μM[1].
Lomitapide-d8 is deuterium labeled Lomitapide. Lomitapide (AEGR-733; BMS-201038) is a potent inhibitor of microsomal triglyceride-transfer protein (MTP) with an IC50 of 8 nM in vitro.