(R)-Exatecan Intermediate 1

Modify Date: 2025-08-24 20:54:29

(R)-Exatecan Intermediate 1 Structure
(R)-Exatecan Intermediate 1 structure
Common Name (R)-Exatecan Intermediate 1
CAS Number 110351-91-2 Molecular Weight 263.25
Density N/A Boiling Point N/A
Molecular Formula C13H13NO5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (R)-Exatecan Intermediate 1


(R)-Exatecan Intermediate 1 is an isomer of Exatecan Intermediate 1 (HY-42487). Exatecan Intermediate 1 (compound 6) is an intermediate of Exatecan (HY-13631), a camptothecin-based anticancer agent. Exatecan inhibits tumor growth by interfering with the proliferation and division of tumor cells by interacting with DNA. Exatecan is primarily used in research into a variety of cancers including ovarian, lung and breast cancer[1][2].

 Names

Name 5'(R)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3',4'-f]Δ6,8-tetrahydroindolizine
Synonym More Synonyms

 (R)-Exatecan Intermediate 1 Biological Activity

Description (R)-Exatecan Intermediate 1 is an isomer of Exatecan Intermediate 1 (HY-42487). Exatecan Intermediate 1 (compound 6) is an intermediate of Exatecan (HY-13631), a camptothecin-based anticancer agent. Exatecan inhibits tumor growth by interfering with the proliferation and division of tumor cells by interacting with DNA. Exatecan is primarily used in research into a variety of cancers including ovarian, lung and breast cancer[1][2].
Related Catalog

 Chemical & Physical Properties

Molecular Formula C13H13NO5
Molecular Weight 263.25
Exact Mass 263.07900
PSA 85.60000
LogP 0.08910
InChIKey IGKWOGMVAOYVSJ-CYBMUJFWSA-N
SMILES CCC1(O)C(=O)OCc2c1cc1n(c2=O)CCC1=O

 Precursor & DownStream

Precursor  0

DownStream  1

 Synonyms

(4R)-4-ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione
.5'(R)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3',4'-f]
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