(R)-Exatecan Intermediate 1
(R)-Exatecan Intermediate 1 structure
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Common Name | (R)-Exatecan Intermediate 1 | ||
|---|---|---|---|---|
| CAS Number | 110351-91-2 | Molecular Weight | 263.25 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C13H13NO5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of (R)-Exatecan Intermediate 1(R)-Exatecan Intermediate 1 is an isomer of Exatecan Intermediate 1 (HY-42487). Exatecan Intermediate 1 (compound 6) is an intermediate of Exatecan (HY-13631), a camptothecin-based anticancer agent. Exatecan inhibits tumor growth by interfering with the proliferation and division of tumor cells by interacting with DNA. Exatecan is primarily used in research into a variety of cancers including ovarian, lung and breast cancer[1][2]. |
Summary: Chinese name: (R)-4-Ethyl-4-hydroxy-7,8-dihydro-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione; English name: 5'(R)-1,5-Dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3',4'-f]Δ6,8-tetrahydroindolizine; CAS number: 110351-91-2; molecular formula: C13H13NO5; molecular weight: 263.25. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 5'(R)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3',4'-f]Δ6,8-tetrahydroindolizine |
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| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | (R)-Exatecan Intermediate 1 is an isomer of Exatecan Intermediate 1 (HY-42487). Exatecan Intermediate 1 (compound 6) is an intermediate of Exatecan (HY-13631), a camptothecin-based anticancer agent. Exatecan inhibits tumor growth by interfering with the proliferation and division of tumor cells by interacting with DNA. Exatecan is primarily used in research into a variety of cancers including ovarian, lung and breast cancer[1][2]. |
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| Related Catalog |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Molecular Formula | C13H13NO5 |
|---|---|
| Molecular Weight | 263.25 |
| Exact Mass | 263.07900 |
| PSA | 85.60000 |
| LogP | 0.08910 |
| InChIKey | IGKWOGMVAOYVSJ-CYBMUJFWSA-N |
| SMILES | CCC1(O)C(=O)OCc2c1cc1n(c2=O)CCC1=O |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 0 | |
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| DownStream 1 | |
CAS#:110351-92-3This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| (4R)-4-ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione |
| .5'(R)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3',4'-f] |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the molecular weight of 5'(R)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3',4'-f]Δ6,8-tetrahydroindolizine? |
| A: Molecular weight of 5'(R)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3',4'-f]Δ6,8-tetrahydroindolizine is 263.25. |
| Q: What is the SMILES notation of 5'(R)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3',4'-f]Δ6,8-tetrahydroindolizine? |
| A: SMILES notation of 5'(R)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3',4'-f]Δ6,8-tetrahydroindolizine is CCC1(O)C(=O)OCc2c1cc1n(c2=O)CCC1=O. |
| Q: What is the InChIKey of 5'(R)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3',4'-f]Δ6,8-tetrahydroindolizine? |
| A: InChIKey of 5'(R)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3',4'-f]Δ6,8-tetrahydroindolizine is IGKWOGMVAOYVSJ-CYBMUJFWSA-N. |
| Q: What English synonyms does 5'(R)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3',4'-f]Δ6,8-tetrahydroindolizine have? |
| A: English synonyms of 5'(R)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3',4'-f]Δ6,8-tetrahydroindolizine: (4R)-4-ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione, .5'(R)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3',4'-f]. |
| Q: What are the downstream products of 5'(R)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3',4'-f]Δ6,8-tetrahydroindolizine? |
| A: Related downstream products(CAS) of 5'(R)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3',4'-f]Δ6,8-tetrahydroindolizine: 110351-92-3. |
| Q: What is the English name of 5'(R)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3',4'-f]Δ6,8-tetrahydroindolizine? |
| A: The English name of 5'(R)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3',4'-f]Δ6,8-tetrahydroindolizine is 5'(R)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3',4'-f]Δ6,8-tetrahydroindolizine. |
| Q: What is the LogP of 5'(R)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3',4'-f]Δ6,8-tetrahydroindolizine? |
| A: LogP of 5'(R)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3',4'-f]Δ6,8-tetrahydroindolizine is 0.08910. |
| Q: What is the molecular formula of 5'(R)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3',4'-f]Δ6,8-tetrahydroindolizine? |
| A: Molecular formula of 5'(R)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3',4'-f]Δ6,8-tetrahydroindolizine is C13H13NO5. |
| Q: What is the polar surface area (PSA) of 5'(R)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3',4'-f]Δ6,8-tetrahydroindolizine? |
| A: Polar surface area (PSA) of 5'(R)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3',4'-f]Δ6,8-tetrahydroindolizine is 85.60000. |
| Q: What is the CAS number of 5'(R)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3',4'-f]Δ6,8-tetrahydroindolizine? |
| A: CAS number of 5'(R)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3',4'-f]Δ6,8-tetrahydroindolizine is 110351-91-2. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |