(R)-Exatecan Intermediate 1

Names

[ Name ]:
(R)-Exatecan Intermediate 1

[Synonym ]:
(4R)-4-ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione
.5'(R)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3',4'-f]

Biological Activity

[Description]:

(R)-Exatecan Intermediate 1 is an isomer of Exatecan Intermediate 1 (HY-42487). Exatecan Intermediate 1 (compound 6) is an intermediate of Exatecan (HY-13631), a camptothecin-based anticancer agent. Exatecan inhibits tumor growth by interfering with the proliferation and division of tumor cells by interacting with DNA. Exatecan is primarily used in research into a variety of cancers including ovarian, lung and breast cancer[1][2].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₃H₁₃NO₅

[ Molecular Weight ]:
263.25

[ Exact Mass ]:
263.07900

[ PSA ]:
85.60000

[ LogP ]:
0.08910

Precursor & DownStream

Precursor

DownStream

Related Compounds

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