Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Paecilaminol

Paecilaminol (FKI-0550) is potent NADH-fumarate reductase inhibitor. Paecilaminol exhibits an IC50 value of 5.1 μM against Ascaris suum NADH-fumarate reductase[1].

  • CAS Number: 540770-33-0
  • MF: C20H43NO
  • MW: 313.56200
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Anti-osteoporosis agent-3

Anti-osteoporosis agent-3 (Compound 11), a PMSA derivative, is an anti-osteoporosis agent. Anti-osteoporosis agent-3 inhibits osteoclastogenesis with an IC50 value of 322.9 nM in vitro. Anti-osteoporosis agent-3 also blocks the formation of F-action belts and bone resorption[1].

  • CAS Number: 2944463-16-3
  • MF: C22H20N2O3S
  • MW: 392.47
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Nemorubicin

Nemorubicin is a derivative of doxorubicin, and has antitumor activity.

  • CAS Number: 108852-90-0
  • MF: C32H37NO13
  • MW: 643.635
  • Catalog: G-quadruplex
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 852.2±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 469.2±34.3 °C

H-Arg(Mtr)-OH.1/2H2O

H-Arg(Mtr)-OH is an arginine derivative[1].

  • CAS Number: 80745-10-4
  • MF: C16H26N4O5S
  • MW: 386.46600
  • Catalog: Others
  • Density: 1.36g/cm3
  • Boiling Point: 615.4ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 326ºC

laccaic acid c

Laccaic acid C is an potent inhibitor of RNase H with an IC50 of 8.1 μM. Laccaic acid C also inhibits viral proliferation in cell [1].

  • CAS Number: 23241-56-7
  • MF: C25H17NO13
  • MW: 539.40100
  • Catalog: Infection
  • Density: 1.863g/cm3
  • Boiling Point: 970.965ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 541.02ºC

Tripeptide-10

Tripeptide-10 is a bioactive peptide withanti-wrinkleeffect and has been reported used as a cosmetic ingredient[1].

  • CAS Number: 515835-71-9
  • MF: C16H30N4O6
  • MW: 374.433
  • Catalog: Metabolic Disease
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 735.0±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 398.3±32.9 °C

Altholactone

Goniothalenol is a styryl lactone that can be isolated from Goniothalamus griffithii. Goniothalenol exhibits cytatoxic activity against A2780, HCT-8, KB and MCF-7 cell lines[1].

  • CAS Number: 65408-91-5
  • MF: C13H12O4
  • MW: 232.23
  • Catalog: Cancer
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 490.4±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 196.1±22.2 °C

Imidazolo-oxindole PKR inhibitor C16

PKR-IN-C16 is a specific protein kinase (PKR) inhibitor. PKR-IN-C16 is able to inhibit the autophosphorylation of PKR and unlock the translation blockade induced by PKR in primary neuronal cultures[1].

  • CAS Number: 608512-97-6
  • MF: C13H8N4OS
  • MW: 268.294
  • Catalog: Neurological Disease
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 674.6±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 361.8±31.5 °C

N-((RS)-2-Hydroxy-propyl)-Val-Leu-anilide

N-((RS)-2-Hydroxy-propyl)-Val-Leu-anilide is a biologically active peptide.

  • CAS Number: 282726-24-3
  • MF: C20H33N3O3
  • MW: 363.494
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 609.4±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 322.4±28.7 °C

N-Methylmoranoline

N-Methylmoranoline (MOR 14) is an α-glucosidase inhibitor.

  • CAS Number: 69567-10-8
  • MF: C7H15NO4
  • MW: 177.19800
  • Catalog: Others
  • Density: 1.394g/cm3
  • Boiling Point: 367.2ºC at 760 mmHg
  • Melting Point: 126-128ºC
  • Flash Point: 220.3ºC

Przewalskinic acid A

Przewalskinic acid A is a rare, water-soluble phenolic acid thus far only found in the Salvia przewalskii Maxim herb. Phenolic acids show potent antioxidant activities and potential effects in protecting against brain and heart damage caused by ischemia reperfusion[1].

  • CAS Number: 136112-75-9
  • MF: C18H14O8
  • MW: 358.30
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

LMP2A (426-434)

LMP2A (426-434) is a biological active peptide. (HLA A2.1-restricted epitope from Epstein-Barr Virus latent membrane protein LMP2 (426-434).)

  • CAS Number: 152274-91-4
  • MF: C39H71N9O11S2
  • MW: 906.16
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

AD 0261

AD 0261 is a radical scavenger which displays strong inhibitory action on the generation of lipid peroxides and superoxide anions.

  • CAS Number: 145600-69-7
  • MF: C27H31F2N3O
  • MW: 451.55100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-Tyr(3-NO2)-OH

Fmoc-Tyr(3-NO2)-OH is a tyrosine derivative[1].

  • CAS Number: 136590-09-5
  • MF: C24H20N2O7
  • MW: 448.425
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 704.4±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 379.8±32.9 °C

PA-JF549-NHS

PA-JF549-NHS is a cell-permeable yellow photoactivatable dye (reactive group: NHS ester). PA-JF549-NHS can be used in single molecule tracking and live cell imaging. Cell permeable. (λExcitation/emission~552/572 nm).

  • CAS Number: 1811539-42-0
  • MF: C32H25N5O6
  • MW: 575.57
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-Bromodecane-d21

1-Bromodecane-d21 is the deuterium labeled 1-Bromodecane[1].

  • CAS Number: 98195-39-2
  • MF: C10BrD21
  • MW: 242.30700
  • Catalog: Others
  • Density: 1.166 g/mL at 25ºC
  • Boiling Point: 238ºC(lit.)
  • Melting Point: N/A
  • Flash Point: N/A

Scabioside C

Scabioside C is a main triterpenoid saponin for total secondary saponin (TSS). TSS, from A. raddeana, exhibits the potential anti-breast cancer effect[1].

  • CAS Number: 17233-22-6
  • MF: C41H66O13
  • MW: 766.955
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 881.9±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 260.9±27.8 °C

Methyl undecanoate

Methyl undecanoate is an internal standard in gas-liquid chromatogram[1].

  • CAS Number: 1731-86-8
  • MF: C12H24O2
  • MW: 200.318
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 246.2±3.0 °C at 760 mmHg
  • Melting Point: -10°C
  • Flash Point: 109.4±0.0 °C

G-{d-Arg}-GDSPASSK

G-{d-Arg}-GDSPASSK is a polypeptide that prevents cell adhesion, is used for wound healing, and allows tissue repair[1].

  • CAS Number: 133640-14-9
  • MF: C37H64N14O16
  • MW: 960.99
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

tert-Butyl 2-((diphenylmethylene)amino)acetate

N-(Diphenylmethylene)glycine tert-butyl ester is a dye, also as the raw material and intermediate for organic syntheses[1][2].

  • CAS Number: 81477-94-3
  • MF: C19H21NO2
  • MW: 295.375
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 377.5±34.0 °C at 760 mmHg
  • Melting Point: 111-115ºC
  • Flash Point: 134.5±20.1 °C

2-(1,3-thiazol-2-yldisulfanyl)-1,3-thiazole

FBPase-IN-1 is a potent FBPase (Fructose-1,6-bisphosphatase) inhibitor for Type 2 diabetes (T2D) study with an IC50 of 0.22 μM. FBPase-IN-1 can reduce blood glucose levels and ameliorate glucose tolerance. FBPase-IN-1 modifies the C128 site, regulates the N125-S124-S123 allosteric pathway of FBPase and affects the catalytic activity of FBPase[1].

  • CAS Number: 20362-54-3
  • MF: C6H4N2S4
  • MW: 232.36900
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Resorcinol (monoacetate)

Resorcinol monoacetate is an antiseptic and a disinfectant, is a chemical intermediate for the production of many other pharmaceuticals, and can be used to treat acne, seborrheic dermatitis, eczema, psoriasis, and other skin disorders.

  • CAS Number: 102-29-4
  • MF: C8H8O3
  • MW: 152.14700
  • Catalog: Inflammation/Immunology
  • Density: 1.223 g/mL at 25 °C(lit.)
  • Boiling Point: 283 °C(lit.)
  • Melting Point: 129-133 °C
  • Flash Point: >230 °F

(2E,4E)-8-Hydroxy-2,7-dimethyl-decadien-(2,4)-disaeure-(1,10)-dioic acid

(2E,4E)-8-Hydroxy-2,7-dimethyl-decadien-(2,4)-disaeure-(1,10)-dioic acid is a nature product that could be isolated form bunge auriculate flower. (2E,4E)-8-Hydroxy-2,7-dimethyl-decadien-(2,4)-disaeure-(1,10)-dioic acid has antioxidant and anti-inflammatory active[1].

  • CAS Number: 2808401-10-5
  • MF: C12H18O5
  • MW: 242.27
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-Nitropropanoic acid

3-Nitropropanoic acid is an irreversible inhibitor of succinate dehydrogenase.

  • CAS Number: 504-88-1
  • MF: C3H5NO4
  • MW: 119.076
  • Catalog: Metabolic Disease
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 303.0±25.0 °C at 760 mmHg
  • Melting Point: 68-70ºC(lit.)
  • Flash Point: 148.4±11.6 °C

((4-(tert-Butyl)phenyl)sulfonyl)methionine

((4-(tert-Butyl)phenyl)sulfonyl)methionine can be used for peptide synthesis.

  • CAS Number: 1393654-69-7
  • MF: C15H23NO4S2
  • MW: 345.48
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-Hexacosane-d54

N-Hexacosane-d54 is the deuterium labeled N-hexacosane[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Notoginsenoside R3

Notoginsenoside R3 is an isolated natural compound.

  • CAS Number: 87741-76-2
  • MF: C48H82O19
  • MW: 963.15
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

triptobenzene H

Triptobenzene H (Hypoglic acid) significantly increases TNF-α and IL-1β mRNA levels in macrophages, causing indirect liver damage[1].

  • CAS Number: 146900-55-2
  • MF: C21H28O4
  • MW: 344.44
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 529.9±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 184.5±23.6 °C

Escin Ie

Escin Ie is a derivative of Aescine in Aesculi Semen extract[1].

  • CAS Number: 1613506-26-5
  • MF: C49H76O19
  • MW: 969.12
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Phe-OEt.HCl

Ethyl L-phenylalaninate hydrochloride is a phenylalanine derivative[1].

  • CAS Number: 3182-93-2
  • MF: C11H16ClNO2
  • MW: 229.703
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 281.3ºC at 760mmHg
  • Melting Point: 155-156 °C(lit.)
  • Flash Point: 140.3ºC