Anti-osteoporosis agent-3

Modify Date: 2025-08-25 07:01:47

Anti-osteoporosis agent-3 Structure
Anti-osteoporosis agent-3 structure
Common Name Anti-osteoporosis agent-3
CAS Number 2944463-16-3 Molecular Weight 392.47
Density N/A Boiling Point N/A
Molecular Formula C22H20N2O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Anti-osteoporosis agent-3


Anti-osteoporosis agent-3 (Compound 11), a PMSA derivative, is an anti-osteoporosis agent. Anti-osteoporosis agent-3 inhibits osteoclastogenesis with an IC50 value of 322.9 nM in vitro. Anti-osteoporosis agent-3 also blocks the formation of F-action belts and bone resorption[1].

 Names

Name Anti-osteoporosis agent-3

 Anti-osteoporosis agent-3 Biological Activity

Description Anti-osteoporosis agent-3 (Compound 11), a PMSA derivative, is an anti-osteoporosis agent. Anti-osteoporosis agent-3 inhibits osteoclastogenesis with an IC50 value of 322.9 nM in vitro. Anti-osteoporosis agent-3 also blocks the formation of F-action belts and bone resorption[1].
Related Catalog
References

[1]. Chen Z, et al. Discovery of PMSA Derivative 11 as a Novel Lead Compound for Therapeutic Treatment of Osteoporosis In Vitro and In Vivo. J Med Chem. 2023 May 25;66(10):6766-6781.  

 Chemical & Physical Properties

Molecular Formula C22H20N2O3S
Molecular Weight 392.47
InChIKey JJEBAPYSUWLIPS-UHFFFAOYSA-N
SMILES COC(=O)c1cccc(NCC(=O)Nc2ccccc2Sc2ccccc2)c1
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