Anti-osteoporosis agent-3

Names

[ Name ]:
Anti-osteoporosis agent-3

Biological Activity

[Description]:

Anti-osteoporosis agent-3 (Compound 11), a PMSA derivative, is an anti-osteoporosis agent. Anti-osteoporosis agent-3 inhibits osteoclastogenesis with an IC50 value of 322.9 nM in vitro. Anti-osteoporosis agent-3 also blocks the formation of F-action belts and bone resorption[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Chen Z, et al. Discovery of PMSA Derivative 11 as a Novel Lead Compound for Therapeutic Treatment of Osteoporosis In Vitro and In Vivo. J Med Chem. 2023 May 25;66(10):6766-6781.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₂₀N₂O₃S

[ Molecular Weight ]:
392.47

Related Compounds

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