3-Nitropropanoic acid
3-Nitropropanoic acid structure
|
Common Name | 3-Nitropropanoic acid | ||
|---|---|---|---|---|
| CAS Number | 504-88-1 | Molecular Weight | 119.076 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 303.0±25.0 °C at 760 mmHg | |
| Molecular Formula | C3H5NO4 | Melting Point | 68-70ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | 148.4±11.6 °C | |
| Symbol |
GHS06 |
Signal Word | Danger | |
Use of 3-Nitropropanoic acid3-Nitropropanoic acid is an irreversible inhibitor of succinate dehydrogenase. |
| Name | 3-nitropropanoic acid |
|---|---|
| Synonym | More Synonyms |
| Description | 3-Nitropropanoic acid is an irreversible inhibitor of succinate dehydrogenase. |
|---|---|
| Related Catalog | |
| Target |
succinate dehydrogenase[1] |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 303.0±25.0 °C at 760 mmHg |
| Melting Point | 68-70ºC(lit.) |
| Molecular Formula | C3H5NO4 |
| Molecular Weight | 119.076 |
| Flash Point | 148.4±11.6 °C |
| Exact Mass | 119.021858 |
| PSA | 83.12000 |
| LogP | -0.08 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
| Index of Refraction | 1.463 |
| Stability | Stable. Incompatible with strong oxidizing agents, bases, reducing agents. |
| Water Solubility | alcohol: 100 mg/mL, may be light yellow |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
|
| Symbol |
GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301 |
| Precautionary Statements | Missing Phrase - N15.00950417 |
| Personal Protective Equipment | Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges |
| Hazard Codes | T |
| Risk Phrases | 25-36/37/38 |
| Safety Phrases | 26-45 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | UF6220000 |
| Packaging Group | III |
| Hazard Class | 6.1(b) |
| HS Code | 2915900090 |
|
~96%
3-Nitropropanoi... CAS#:504-88-1 |
| Literature: COUNCIL OF SCIENTIFIC and INDUSTRIAL RESEARCH; Kamal, Ahmed; Murty, Jayanti Naga Srirama Chandra; Viswanath, Arutla Patent: US2013/317211 A1, 2013 ; Location in patent: Paragraph 0271 ; |
|
~98%
3-Nitropropanoi... CAS#:504-88-1 |
| Literature: Annese, Cosimo; D'Accolti, Lucia; Filardi, Rosella; Tommasi, Immacolata; Fusco, Caterina Tetrahedron Letters, 2013 , vol. 54, # 6 p. 515 - 517 |
|
~%
3-Nitropropanoi... CAS#:504-88-1 |
| Literature: Hass; Hudgin Journal of the American Chemical Society, 1954 , vol. 76, p. 2692 |
|
~72%
3-Nitropropanoi... CAS#:504-88-1 |
| Literature: Addo, James K.; Teesdale-Spittle, Paul; Hoberg, John O. Synthesis, 2005 , # 12 art. no. M09404SS, p. 1923 - 1925 |
|
~%
3-Nitropropanoi... CAS#:504-88-1 |
| Literature: Gresham et al. Journal of the American Chemical Society, 1952 , vol. 74, p. 1323 Full Text View citing articles Show Details Hass et al. Journal of the American Chemical Society, 1951 , vol. 73, p. 1858 |
|
~%
3-Nitropropanoi... CAS#:504-88-1 |
| Literature: Lewkowitsch Journal fuer Praktische Chemie (Leipzig), 1879 , vol. <2>20, p. 169 |
|
~%
3-Nitropropanoi... CAS#:504-88-1 |
| Literature: Hass; Hudgin Journal of the American Chemical Society, 1954 , vol. 76, p. 2692 |
| Precursor 6 | |
|---|---|
| DownStream 7 | |
CAS#:20497-95-4
CAS#:3590-37-2
CAS#:690-39-1
CAS#:107-95-9
CAS#:25182-84-7
CAS#:75640-08-3
CAS#:51834-15-2| HS Code | 2915900090 |
|---|---|
| Summary | 2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0% |
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Suppression of Cpn10 increases mitochondrial fission and dysfunction in neuroblastoma cells.
PLoS ONE 9(11) , e112130, (2014) To date, several regulatory proteins involved in mitochondrial dynamics have been identified. However, the precise mechanism coordinating these complex processes remains unclear. Mitochondrial chapero... |
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Quantification of nitropropanoyl glucosides in karaka nuts before and after treatment.
Food Chem. 175 , 543-8, (2015) A high performance liquid chromatography (HPLC) method was developed to assay nitropropanoyl glucosides in the nuts of karaka (Corynocarpus laevigatus) a traditional food of New Zealand Māori. Levels ... |
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Naringin modulates oxidative stress and inflammation in 3-nitropropionic acid-induced neurodegeneration through the activation of nuclear factor-erythroid 2-related factor-2 signalling pathway.
Neuroscience 227 , 134-43, (2012) Nuclear factor-erythroid 2-related factor-2 (Nrf2) mediated regulation of cellular antioxidant production and the anti-inflammatory mechanism play an important role in neuroprotection against neurodeg... |
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