Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Fmoc-L-cysteine

(((9H-Fluoren-9-yl)methoxy)carbonyl)-L-cysteine is a cysteine derivative[1].

  • CAS Number: 135248-89-4
  • MF: C18H17NO4S
  • MW: 343.397
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 574.4±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 301.2±30.1 °C

sodium cyanoborodeuteride

Sodium cyanoboronhydride-d3 is the deuterium labeled Sodium cyanoboronhydride[1].

  • CAS Number: 25895-62-9
  • MF: CBD3NNa
  • MW: 65.86050
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: >242ºC (dec.)(lit.)
  • Flash Point: N/A

O4I4

O4I4 (compound 23) is a OCT4-inducing compound with metabolical stability. O4I4 extends lifespan in Caenorhabditis elegans and Drosophila. O4I4 can be used for regenerative medicine and rejuvenation research[1].

  • CAS Number: 412008-21-0
  • MF: C15H20N2S
  • MW: 260.40
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

ACTH (1-13)

ACTH (1-13) is a 13-aa peptide, with cytoprotective effects in the model of ethanol induced gastric lesions in rats.

  • CAS Number: 22006-64-0
  • MF: C75H106N20O19S
  • MW: 1623.83000
  • Catalog: Peptides
  • Density: 1.49g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Relatlimab

Relatlimab (BMS-986016) is a human monoclonal antibody anti-LAG-3 antibody generated by immunization of transgenic mice bearing human immunoglobulin miniloci with recombinant LAG-3 protein. Relatlimab blocks LAG-3/MHC II interaction with an IC50 value of 0.67 nM and LAG-3/FGL1 interaction with an IC50 value of 0.019 nM. Relatlimab can be used in research of cancer[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Glu(OtBu)-OtBu

H-Glu(OtBu)-OtBu is a glutamic acid derivative[1].

  • CAS Number: 16874-06-9
  • MF: C13H25NO4
  • MW: 259.34200
  • Catalog: Others
  • Density: 1.020±0.06 g/cm3(Predicted)
  • Boiling Point: 311.1±27.0 °C(Predicted)
  • Melting Point: 139-141°C (dec.)
  • Flash Point: N/A

Z-Gly-Gly-Arg-AMC

Z-Gly-Gly-Arg-AMC is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP). Sequence: Z-Gly-Gly-Arg-AMC.

  • CAS Number: 66216-78-2
  • MF: C28H33N7O7
  • MW: 579.60400
  • Catalog: Peptides
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sodium Glycinate

Sodium 2-aminoacetate is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 6000-44-8
  • MF: C2H4NNaO2
  • MW: 97.048
  • Catalog: Others
  • Density: 1.014g/cm3
  • Boiling Point: 240.9ºC at 760 mmHg
  • Melting Point: 290ºC decomposes
  • Flash Point: 99.5ºC

Calcitonin C-Terminal Flanking Peptide (human) trifluoroacetate salt

Katacalcin is a second potent plasma calcium-lowering peptide.

  • CAS Number: 85916-47-8
  • MF: C97H154N34O36S2
  • MW: 2436.60000
  • Catalog: Peptides
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Hydroxynaphthol blue

Hydroxynaphthol Blue enables visual tube closure detection. Hydroxynaphthol Blue shows high specificity for the gene encoding Ara h 1 for visual field detection of peanut allergens[1].

  • CAS Number: 63451-35-4
  • MF: C20H11N2Na3O11S3
  • MW: 620.47
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ara-F-NAD+

Ara-F-NAD+, an arabino analogue of NAD+, is a potent, slow-binding CD38 NADase inhibitor, with a Ki of 169 nM[1][2].

  • CAS Number: 133575-27-6
  • MF: C21H26FN7O13P2
  • MW: 665.42
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ibiglustat succinate

Ibiglustat (Venglustat) succinate is an orally active, brain-penetrant glucosylceramide synthase (GCS) inhibitor. Ibiglustat succinate can be used for the research of Gaucher disease type 3, Parkinson's disease associated with GBA mutations, Fabry disease, GM2 gangliosidosis, and autosomal dominant polycystic kidney disease[1][2].

  • CAS Number: 1629063-80-4
  • MF: C24H30FN3O6S
  • MW: 507.57
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Alpertine

Alpertine is an antipsychotic agent extracted from patent US 5955459 A.

  • CAS Number: 27076-46-6
  • MF: C25H31N3O4
  • MW: 437.53100
  • Catalog: Neurological Disease
  • Density: 1.195g/cm3
  • Boiling Point: 616.5ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 326.7ºC

Thymidine diphosphate-L-rhamnose

Thymidine-5'-diphosphate-L-rhamnose disodium can be isolated from Occhromonas malhamensis[1].

  • CAS Number: 2147-59-3
  • MF: C16H26N2O15P2
  • MW: 548.330
  • Catalog: Others
  • Density: 1.8±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Z-D-Dbu(N3)-OH

Z-D-Dbu(N3)-OH is a click chemistry reagent containing an azide group. Z-D-Dbu(N3)-OH can be used for the research of various biochemical[1].

  • CAS Number: 1931958-82-5
  • MF: C12H14N4O4
  • MW: 278.26
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Interiotherin D

Interiotherin D is a lignan that can be isolated from Kadsura interior[1].

  • CAS Number: 460090-66-8
  • MF: C26H26O8
  • MW: 466.48
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

PBB3

PBB3, a selective PET ligand, recognizes tau pathology in Alzheimer's disease brains, where dystrophic neurites and diffuse neurofibrils are more clearly detected Tangles with calcification[1].

  • CAS Number: 1565796-97-5
  • MF: C17H15N3OS
  • MW: 309.39
  • Catalog: Neurological Disease
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 572.4±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 300.0±32.9 °C

Dexamethasone 9,11-epoxide

Dexamethasone 9,11-epoxide, a compound extracted from patent CN 106520896 A and RU 2532902 C1, is an intermediate in the preparation of dexamethasone.

  • CAS Number: 24916-90-3
  • MF: C22H28O5
  • MW: 372.455
  • Catalog: Inflammation/Immunology
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 564.9±50.0 °C at 760 mmHg
  • Melting Point: 210-220ºC
  • Flash Point: 198.1±23.6 °C

FATP1-IN-2

FATP1-IN-2, as an arylpiperazine derivative, is an orally active fatty acid transport protein 1 (FATP1) inhibitor (human IC50=0.43 μM, mouse IC50=0.39 μM)[1].

  • CAS Number: 2650944-83-3
  • MF: C19H20FN5O
  • MW: 353.39
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

dioxybenzone

Dioxybenzone is an organic compound used in sunscreen to block UVB and short-wave UVA (ultraviolet) rays.

  • CAS Number: 131-53-3
  • MF: C14H12O4
  • MW: 244.243
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 375.0±0.0 °C at 760 mmHg
  • Melting Point: 73-75 °C(lit.)
  • Flash Point: 146.0±18.6 °C

6-Chloro-1H-indol-3-yl β-D-galactopyranoside

Rose-β-D-Gal is a flurescent dye, is also a β-galactosidase substrate. Rose-β-D-Gal creates a pink/magenta color after the reaction and has been used for detection of β-gal activity[1][2].

  • CAS Number: 138182-21-5
  • MF: C14H16ClNO6
  • MW: 329.733
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 630.2±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 335.0±31.5 °C

WAY-621924

WAY-621924 is an active molecule.

  • CAS Number: 745789-70-2
  • MF: C17H14N2O2S
  • MW: 310.37
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Lucerastat

Lucerastat, the galactose form of Miglustat, is an orally-available inhibitor of glucosylceramide synthase (GCS). Lucerastat has the potential for Fabry disease study[1][2].

  • CAS Number: 141206-42-0
  • MF: C10H21NO4
  • MW: 219.27800
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Astragaloside

Astragaloside protects the morphological structures and restores acetylcholine level in rat hippocampus, and improves brain functions via normalizing brain EEG[1].

  • CAS Number: 17429-69-5
  • MF: C28H32O17
  • MW: 640.54
  • Catalog: Neurological Disease
  • Density: 1.8±0.1 g/cm3
  • Boiling Point: 1000.6±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 327.5±27.8 °C

Z-D-Tyt(tBu)-OH.DCHA

Z-D-Tyr(tBu)-OH.DCHA is a tyrosine derivative[1].

  • CAS Number: 198828-72-7
  • MF: C33H48N2O5
  • MW: 552.745
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Glyoxalase I inhibitor 4

Glyoxalase I inhibitor 4 (compound 14) is a potent glyoxalase I inhibitor with an Ki of 10 nM[1].

  • CAS Number: 250155-72-7
  • MF: C17H21IN4O8S
  • MW: 568.34
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(2R,4S)-H-D-Pro(4-N3)-OH

(2R,4S)-H-D-Pro(4-N3)-OH is a click chemistry reagent containing an azide group[1].

  • CAS Number: 2137086-50-9
  • MF: C5H8N4O2
  • MW: 156.14
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

SOD

Superoxide dismutase (SOD) is the only antioxidant enzyme that scavenges the superoxide anion by converting this free radical to oxygen and hydrogen peroxide, thus preventing peroxynitrite production and further damage. Superoxide dismutase is extensively researched and used in anti-inflammatory, antitumor, radiation protection, and antisenility applications[1].

  • CAS Number: 9054-89-1
  • MF:
  • MW: 203.151
  • Catalog: Cancer
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 359.1±42.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 183.5±20.7 °C

2,3,5,6-Tetrachloroaniline-d3

2,3,5,6-Tetrachloroaniline-d3 is the deuterium labeled 2,3,5,6-Tetrachloroaniline[1].

  • CAS Number: 1219806-05-9
  • MF: C6D3Cl4N
  • MW: 233.93
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cellopentaose

Cellopentaose is a penta oligosaccharide of cellulose[1].

  • CAS Number: 2240-27-9
  • MF: C30H52O26
  • MW: 828.718
  • Catalog: Others
  • Density: 1.8±0.1 g/cm3
  • Boiling Point: 1253.2±65.0 °C at 760 mmHg
  • Melting Point: 245-268ºC
  • Flash Point: 385.5±27.8 °C