Ara-F-NAD+

Modify Date: 2024-01-09 00:33:22

Ara-F-NAD+ structure	Common Name	Ara-F-NAD+
	CAS Number	133575-27-6	Molecular Weight	665.42
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₆FN₇O₁₃P₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Ara-F-NAD+

Ara-F-NAD+, an arabino analogue of NAD+, is a potent, slow-binding CD38 NADase inhibitor, with a Ki of 169 nM[1][2].

Name	Ara-F-NAD+

Description	Ara-F-NAD+, an arabino analogue of NAD+, is a potent, slow-binding CD38 NADase inhibitor, with a Ki of 169 nM[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
In Vitro	The leucoyte surface antigen CD38 has been shown to be an ecto-enzyme with multiple catalytic activities. It is principally a NAD+ glycohydrolase that transforms NAD+ into ADP-ribose and nicotinamide. CD38 is also able to produce small amounts of cyclic ADP-ribose (ADP-ribosyl cyclase activity) and to hydrolyse this cyclic metabolite into ADP-ribose (cyclic ADP-ribose hydrolase activity)[1].
References	[1]. Berthelier V, et al. Human CD38 is an authentic NAD(P)+ glycohydrolase. Biochem J. 1998;330 ( Pt 3)(Pt 3):1383-1390. doi:10.1042/bj3301383 [2]. Wang S, et al. Design, synthesis and SAR studies of NAD analogues as potent inhibitors towards CD38 NADase. Molecules. 2014;19(10):15754-15767. Published 2014 Sep 29.

Molecular Formula	C₂₁H₂₆FN₇O₁₃P₂
Molecular Weight	665.42

DC Chemicals Limited
China
Product Name: Ara-F-NAD+
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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