(rac)-Modipafant-d4 (UK-74505-d4) is the deuterium labeled (Rac)-Modipafant. (Rac)-Modipafant (UK-74505) is an orally active, selective, long-acting irreversible platelet activating factor receptor (PAFR) antagonist. (Rac)-Modipafant prevents dengue infection[1][2][3].
METTL3-IN-1 (compound 23) is a polyheterocyclic compound, acts as METTL3 inhibitor[1].
Picropodophyllin-β-D-glucoside (compound 3) is a podophyllotoxin glucoside isolated from Chinese medicinal plants[1].
Cytidine 5'-Triphosphate (ammonium salt)-d8 is the deuterium labeled Cytidine 5'-Triphosphate ammonium salt[1].
Devaleryl Valsartan Impurity is an intermediate in the synthesis of Valsartan[1].
IACS-10759 is a potent inhibitor of complex I of oxidative phosphorylation (OXPHOS).
Musk tibetene (Musk tibetine) is a nitro musk compound with carcinogenic activity. Musk tibetine reveals no genotoxicity in the micronucleus test with human lymphocytes and human hepatoma cell line[1][2].
Guluronic acid (G2013), one of the organic building blocks of hyaluronic acid, is a nonsteroidal anti-inflammatory agent has favorable anti-inflammatory effect[1][2].
Haloperidol decanoate shows antipsychotic activity. Haloperidol decanoate can be used in schizophrenia and schizoaffective disorder research[1].
Cyclosporin is a cyclic decapeptide that could be isolated form the soil fungi Tolypocladium inflatum. Cyclosporin is an immunosuppressant thought to bind to cyclophilin in T-lymphocytes[1].
WAY-608119 is an active molecule.
cis-Tiliroside, a kaempferol derivative, is a flavonoid glycoside. cis-Tiliroside exhibits better cytotoxic activity than trans-Tiliroside in A549 cell line[1].
2R,4S-Sacubitril is the impurity of Sacubitril. Sacubitril is approved by the Food and Drug Administration for use in combination with valsartan for the treatment of patients with heart failure.
L-β-Homolysine dihydrochloride is a lysine derivative[1].
N-(2,4-Dinitrophenyl)glycine is a Glycine (HY-Y0966) derivative[1].
AS1708727 is an orally active Foxo1 inhibitor, with EC50 values of 0.33 μM and 0.59 μM for G6Pase and PEPCK, respectively[1].
23-epi-26-Deoxyactein is a natural and orally active anti-obesity and anti-cancer compound[1][2][3].
Adipokinetic Hormone (AKH) (24-32), locust is a peptide hormone isolated from locusts.
Quebecol is a nutraceutical agent against periodontitis.
Cajanin is a potent and orally active anti-melanogenic agent. Cajanin shows antiproliferative activity in MNT1 Cells. Cajanin efficiently decreases the melanin content. Cajanin down-regulates the mRNA and protein expression levels of MITF, tyrosinase, TRP-1 and Dct (TRP-2). Cajanin induces cell cycle arrest at G2/M and S phase. Cajanin stimulates osteoblast proliferation. Cajanin has the potential for the research of human hyperpigmented disorders and menopausal osteoporosis[1][2].
N-Demethylansamitocin P-3 can be prepared from Ansamitocin (an antitumor ansamycin antibiotic) by Streptomyces minutiscleroticus IFO 13361[1].
2-((tert-Butoxycarbonyl)amino)-2-cyclobutylacetic acid is a Glycine (HY-Y0966) derivative[1].
L-threo-3-Hydroxyaspartic acid is a potent EAAT inhibitor with Kis of 11, 19 and 14 μM for EAAT1, EAAT2 and EAAT3, respectively in HEK293 cell lines[1].
Tetrahymanol is a pentacyclic triterpenoid that can be found in Tetrahymena pyriformis[1].
N-alpha-Tosyl-L-lysine chloromethyl ketone (TLCK), a trypsin like protease inhibitor, sensitizes HeLa cells to Fas-mediated cell death.
Hydroxy Iloperidone is a metabolite of Iloperidone, which is an atypical antipsychotic.
8-Phenyl-2,6-diethyl-BODIPY 505/515 is a derivative of BODIPY 505/515 (Ex=525 nm，Em=544 nm)[1].
4-Acetylsulfanilamide-13C6 is the 13C6 labeled 4-Acetylsulfanilamide.
27-p-Coumaroyloxyursolic acid (compound 6) is a kind of ulmoidol. 27-p-Coumaroyloxyursolic acid can be isolated from Ilex kudincha. 27-p-Coumaroyloxyursolic acid is an inhibitor of Acyl CoA Cholesteryl Acyl Transferase (ACAT) with an IC50 value of 0.73 μM[1].