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2648257-77-4

2648257-77-4 structure

2648257-77-4 structure

Name: METTL3-IN-1
Chemical Name: METTL3-IN-1
CAS Number: 2648257-77-4
Molecular Formula: C₂₅H₂₄FN₅O₂
Molecular Weight: 445.49
Catalog: Research Areas Others
Create Date: 2023-01-21 23:43:40
Modify Date: 2024-01-02 10:34:50
METTL3-IN-1 (compound 23) is a polyheterocyclic compound, acts as METTL3 inhibitor[1].

Name	METTL3-IN-1

Description	METTL3-IN-1 (compound 23) is a polyheterocyclic compound, acts as METTL3 inhibitor[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
Target	METTL3[1]
In Vitro	METTL3，即 N6 -腺苷甲基转移酶 70 kDa 亚基，是 MT-A 的 70 kDa 亚基。MT-A 是 N6 -腺苷甲基转移酶的一部分。METTL3 参与真核 mRNA 内部腺苷残基的转录后甲基化，形成 N6 -甲基腺苷 (m6A)[2]。
References	[1]. Blackaby WP, et al. Preparation of polyheterocyclic compounds as METTL3 inhibitors: World Intellectual Property Organization, WO2021111124[P]. 2021-06-10. [2]. METTL3, Wikipedia.

Molecular Formula	C₂₅H₂₄FN₅O₂
Molecular Weight	445.49

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