2R,4S-Sacubitril
Modify Date: 2025-08-25 13:05:26
2R,4S-Sacubitril structure
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Common Name | 2R,4S-Sacubitril | ||
|---|---|---|---|---|
| CAS Number | 761373-05-1 | Molecular Weight | 411.491 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 656.9±55.0 °C at 760 mmHg | |
| Molecular Formula | C24H29NO5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 351.1±31.5 °C | |
Use of 2R,4S-Sacubitril2R,4S-Sacubitril is the impurity of Sacubitril. Sacubitril is approved by the Food and Drug Administration for use in combination with valsartan for the treatment of patients with heart failure. |
| Name | 4-{[(2R,4S)-1-(4-Biphenylyl)-5-ethoxy-4-methyl-5-oxo-2-pentanyl]amino}-4-oxobutanoic acid |
|---|---|
| Synonym | More Synonyms |
| Description | 2R,4S-Sacubitril is the impurity of Sacubitril. Sacubitril is approved by the Food and Drug Administration for use in combination with valsartan for the treatment of patients with heart failure. |
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| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 656.9±55.0 °C at 760 mmHg |
| Molecular Formula | C24H29NO5 |
| Molecular Weight | 411.491 |
| Flash Point | 351.1±31.5 °C |
| Exact Mass | 411.204559 |
| LogP | 3.96 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.549 |
| Storage condition | 2-8℃ |
| 4-{[(2R,4S)-1-(4-Biphenylyl)-5-ethoxy-4-methyl-5-oxo-2-pentanyl]amino}-4-oxobutanoic acid |
| [1,1'-Biphenyl]-4-pentanoic acid, γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl-, α-ethyl ester, (αS,γR)- |
| 4-(((2R,4S)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid |
| LCZ696 impurity 18 |
| (alphaS,gammaR)-gamma-[(3-Carboxy-1-oxopropyl)amino]-alpha-methyl-[1,1'-biphenyl]-4-pentanoic acid 4-ethyl ester |
| 2R,4S-Sacubitril |