Fmoc-Abg(N3)-OH is a click chemistry reagent containing an azide group. Fmoc-Abg(N3)-OH has the potential to synthesize peptide nucleic acids (PNA) and peptoids.
Factor VIIa substrate is a colorimetric substrate for Factor VIIa, that can be measured by absorbance at 405 nm[1].
Nα-(2,4-Dinitrophenyl)-L-arginine is an arginine derivative[1].
SB-633825 is a potent and ATP-competitive inhibitor of TIE2, LOK (STK10) and BRK with IC50s of 3.5 nM, 66 nM, 150 nM, respectively. SB-633825 can inhibit cancer cell growth and angiogenesis[1].
1-Bromo-1,1-dichloroacetone is one of the clorine doxide dsinfection bproducts (DBPs) in drinking water[1].
FGF22-IN-1 (compound c1) is a potent CD4 D1 inhibitor. FGF22-IN-1 can be used as immunosuppressive agent[1].
N-563 is an analogue of deoxyspergualin with an immunostimulating activity,it promotes resistance to Candida albicans infection in mice. In vivo: The protective effect of the N-563 against C. albicans infection was investigated in normal and immunosuppressed mice. In normal mice, N-563 treatment at 10 mg/kg for 3 days prior to infection significantly prolonged the survival time. In immunosuppressed mice treated with a single dose of cyclophosphamide 4 days prior to infection, N-563 at 3 and 10 mg/kg for 3 days prior to infection also significantly prolonged the survival time of mice. In addition, it augmented the phagocytic activity of neutrophils and enhanced the delayed type hypersensitivity reaction against C. albicans. Coincidentally, N-563 appeared to protect against secondary infection with C. albicans in the delayed type hypersensitivity-positive mice.[1]N-563 was dissolved in physiological saline and filtered through a Millipore filter (0.22μm).[1]
Dactylorhin A, a succinate derivative ester, is isolated from rhizomes of Gymnadenia conopsea. Dactylorhin A exhibits moderate inhibitory effects on NO production effects in RAW 264.7 macrophage cells[1][2].
BODIPY 493/503 (Pyrromethene 546) is a fluorescent neutral lipid dye (Ex/Em: 493/503 nm). BODIPY 493/503 can facilitate quantification of neutral lipid content by flow cytometry and observation of lipid droplets (LDs) by microscopy[1].
D-Octamannuronic acid, an alginate oligomer, is produced by marine brown algae and by a limited range of Gram negative bacteria. D-Octamannuronic acid can be used for the research of pain and vascular dementia[1][2][3][4].
Leflunomide is a pyrimidine synthesis inhibitor, inhibiting dihydroorotate dehydrogenase, and acts as a disease-modifying antirheumatic drug.
Kuguacin R is a cucurbitane-type triterpenoid that can be extracted from Momordica charantia L. Kuguacin R possess anti-inflammatory, antimicrobial and anti-viral activities[1].
3-Nitrobenzoic acid-d4 is the deuterium labeled 3-Nitrobenzoic acid[1].
Hexa-D-arginine is an inhibitor of furin.
Oxytocin antiparallel dimer is the disulfide-bridged homo peptide dimer[1].
Methyl (E)-cinnamate-d5 is the deuterium labeled Methyl (E)-cinnamate[1]. Methyl (E)-cinnamate (EMC), a phytochemical constituent isolated from Alpinia katsumadai Hayata, is a natural flavor compound with anti-inflammatory properties. Methyl (E)-cinnamate is widely used in the food and commodity industry[2].
Boc-D-Phe(2-Me)-OH is a phenylalanine derivative[1].
Alcesefoliside is a flavonoid isolated from Nitraria sibirica Pall, with antioxidant activity[1].
Pivalic acid-d9 is the deuterium labeled Pivalic acid[1].
Z-Tyr(Bzl)-OH is a tyrosine derivative[1].
Tiplimotide (NBI-5788) is an altered peptide ligand (APL) designed from an immunodominant region (83-99) of the neuroantigen myelin basic protein (MBP). Tiplimotide can selectively reduce the production of inflammatory cytokines by pathogenic T-cells. Tiplimotide can be used for the research of multiple sclerosis (MS)[1][2].
Methyltetrazine-Amine, a tetrazine compound, is used for the site-specific dual functionalization of the resulting bioconjugates[1].
Sweroside, isolated from Lonicera japonica, exhibits cytoprotective, anti-osteoporotic, and hepatoprotective effect[1][2].
Onjisaponin Z is a natural product isolated from Radix Polygalae.
DL-Alaninol hydrochloride is an alanine derivative[1].
Ingenol 20-palmitate (compound 2) is a diterpene that can be found in Euphorbia lath yris[1].
5-(tert-Butyl)isobenzofuran-1,3-dione is a intermediate and dye. 5-(tert-Butyl)isobenzofuran-1,3-dione has a synonym of 4-tert-Butylphthalic Anhydride[1].
2,2'-Dichloro bisphenol a mono-D-glucuronide-d12 is the deuterium labeled 2,2'-Dichloro bisphenol a mono-D-glucuronide[1].
Boc-4,5-dehydro-Leu-OH (dicyclohexylammonium) salt is a leucine derivative[1].
Oreptacog alfa is a recombinant DNA derived human blood coagulation factor VIIa. Oreptacog alfa can be used for the research of hemophilia, congenital factor VII deficiency and Glanzmann's thrombasthenia (GT)[1][2].