Tiplimotide
Modify Date: 2025-08-22 16:32:06
Tiplimotide structure
|
Common Name | Tiplimotide | ||
|---|---|---|---|---|
| CAS Number | 178823-49-9 | Molecular Weight | 1860.207 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C87H142N24O21 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of TiplimotideTiplimotide (NBI-5788) is an altered peptide ligand (APL) designed from an immunodominant region (83-99) of the neuroantigen myelin basic protein (MBP). Tiplimotide can selectively reduce the production of inflammatory cytokines by pathogenic T-cells. Tiplimotide can be used for the research of multiple sclerosis (MS)[1][2]. |
| Name | D-Alanyl-L-lysyl-L-prolyl-L-valyl-L-valyl-L-histidyl-L-leucyl-L-phenylalanyl-L-alanyl-L-asparaginyl-L-isoleucyl-L-valyl-L-threonyl-L-prolyl-L-arginyl-L-threonyl-L-proline |
|---|---|
| Synonym | More Synonyms |
| Description | Tiplimotide (NBI-5788) is an altered peptide ligand (APL) designed from an immunodominant region (83-99) of the neuroantigen myelin basic protein (MBP). Tiplimotide can selectively reduce the production of inflammatory cytokines by pathogenic T-cells. Tiplimotide can be used for the research of multiple sclerosis (MS)[1][2]. |
|---|---|
| Related Catalog |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Molecular Formula | C87H142N24O21 |
| Molecular Weight | 1860.207 |
| Exact Mass | 1859.078125 |
| LogP | 1.38 |
| Index of Refraction | 1.653 |
| InChIKey | NITUEMISTORFON-PPFXTMJRSA-N |
| SMILES | CCC(C)C(NC(=O)C(CC(N)=O)NC(=O)C(C)NC(=O)C(Cc1ccccc1)NC(=O)C(CC(C)C)NC(=O)C(Cc1cnc[nH]1)NC(=O)C(NC(=O)C(NC(=O)C1CCCN1C(=O)C(CCCCN)NC(=O)C(C)N)C(C)C)C(C)C)C(=O)NC(C(=O)NC(C(=O)N1CCCC1C(=O)NC(CCCN=C(N)N)C(=O)NC(C(=O)N1CCCC1C(=O)O)C(C)O)C(C)O)C(C)C |
| D-Alanyl-L-lysyl-L-prolyl-L-valyl-L-valyl-L-histidyl-L-leucyl-L-phenylalanyl-L-alanyl-L-asparaginyl-L-isoleucyl-L-valyl-L-threonyl-L-prolyl-L-arginyl-L-threonyl-L-proline |
| L-Proline, D-alanyl-L-lysyl-L-prolyl-L-valyl-L-valyl-L-histidyl-L-leucyl-L-phenylalanyl-L-alanyl-L-asparaginyl-L-isoleucyl-L-valyl-L-threonyl-L-prolyl-L-arginyl-L-threonyl- |