Furin Inhibitor II trifluoroacetate salt
Modify Date: 2025-08-22 10:04:04
Furin Inhibitor II trifluoroacetate salt structure
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Common Name | Furin Inhibitor II trifluoroacetate salt | ||
|---|---|---|---|---|
| CAS Number | 673202-67-0 | Molecular Weight | 954.14500 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C36H75N25O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Furin Inhibitor II trifluoroacetate saltHexa-D-arginine is an inhibitor of furin. |
| Name | hexa-D-arginine |
|---|---|
| Synonym | More Synonyms |
| Description | Hexa-D-arginine is an inhibitor of furin. |
|---|---|
| Related Catalog | |
| In Vitro | Hexa-D-arginine (10 μM) protects against the cytotoxic effects of anthrax toxin in RAW 264.7 cells. The concentrations of Hexa-D-arginine requires to block the cleavage of PA are similar to those required to inhibit toxicity[2]. |
| In Vivo | Administration of hexa-d-arginine to PEA-treated mice significantly improves their survival rate and also decreases circulating levels of tumor necrosis factor alpha[1]. Rats treated with the combination of anthrax toxins and Hexa-D-arginine exhibit a 40% survival rate at 5 h compared with a control group treated solely with anthrax toxin (0% survival rate). Administration of Hexa-D-arginine (1 mg/100 μL) also results in a considerable delay in the onset of anthrax toxemia compared with results of the control group treated solely with anthrax toxin[2]. |
| References |
| Molecular Formula | C36H75N25O6 |
|---|---|
| Molecular Weight | 954.14500 |
| Exact Mass | 953.63300 |
| PSA | 586.01000 |
| LogP | 2.30330 |
| InChIKey | BMLTZEAFQLJTIZ-TZNXUKFXSA-N |
| SMILES | NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(N)CCCN=C(N)N |
| Storage condition | -20°C |
| FURIN INHIBITOR II |
| Furin Inhibitor II, Hexa-D-arginine amide |