H-D-Phe-Phe-Arg-chloromethylketone trifluoroacetate salt

Modify Date: 2025-08-24 18:15:46

H-D-Phe-Phe-Arg-chloromethylketone trifluoroacetate salt structure	Common Name	H-D-Phe-Phe-Arg-chloromethylketone trifluoroacetate salt
	CAS Number	74392-49-7	Molecular Weight	501.02100
	Density	1.308g/cm3	Boiling Point	N/A
	Molecular Formula	C₂₅H₃₃ClN₆O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of H-D-Phe-Phe-Arg-chloromethylketone trifluoroacetate salt

PPACK II is an irreversible and specific glandular and plasma kallikreins inhibitor[1].

Name	H-D-Phe-Phe-Arg-chloromethylketone
Synonym	More Synonyms

Description	PPACK II is an irreversible and specific glandular and plasma kallikreins inhibitor[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Ser/Thr Protease Research Areas >> Cardiovascular Disease
In Vitro	PPACK II (0.62-50 μg/mL) 显着抑制 B 型钠尿肽 (BNP) 蛋白水解[2]。
References	[1]. Kentaro Takayama, et al. Identification of a degrading enzyme in human serum that hydrolyzes a C-terminal core sequence of neuromedin U. Biopolymers. 2016 Nov 4;106(4):440-5. [2]. Alexander Belenky, et al. The effect of class-specific protease inhibitors on the stabilization of B-type natriuretic peptide in human plasma. Clin Chim Acta. 2004 Feb;340(1-2):163-72.

phenylalanyl-phenylalanyl-argininechloromethylketone

D-Phenylalanyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-(2-chloroacetyl)butyl]-L-phenylalaninamide

H-D-PHE-PHE-ARG-CMK TFA

DPHE-PHE-ARG-CHLOROMETHYLKETONE

D-Phe-Phe-Arg Chloromethylketone Trifluoroacetate Salt

H-D-PHE-PHE-ARG-CHLOROMETHYLKETONE TRIFLUOROACETATE SALT

DPHE-PHE-ARG-CMK

PPACK II,TRIFLUOROACETATE SALT