Chemsrc provides Others's classification. They are divided into Androgen Receptor, Aromatase, Estrogen Receptor/ERR, Progesterone Receptor, Thyroid Hormone Receptor, Others according to their Biological activity.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

RS5517

RS5517 is a specific PDZ1-domain antagonist of NHERF1 that prevented its ectopic nuclear entry. RS5517 can be used for the research of colorectal cancer[1][2].

  • CAS Number: 2227017-46-9
  • MF: C23H19ClN2O2
  • MW: 390.86
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-DL-Ala-DL-Ala-OH

2-(2-Aminopropanamido)propanoic acid is an alanine derivative[1].

  • CAS Number: 2867-20-1
  • MF: C6H12N2O3
  • MW: 160.17100
  • Catalog: Others
  • Density: 1.208g/cm3
  • Boiling Point: 402.6ºC at 760mmHg
  • Melting Point: 268-270ºC
  • Flash Point: 197.3ºC

Androst-4-ene-3,17-diol, dipropanoate, (3β,17β)-

Androst-4-ene-3,17-diol, dipropanoate, (3β,17β)- is the dipropanoate of 4-Androstenediol, a metabolite of testosterone.

  • CAS Number: 56699-31-1
  • MF:
  • MW: 402.57
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

TNIK&MAP4K4-IN-1

TNIK&MAP4K4-IN-1 (compound A-39) is a dual inhibitor of TNIK and MAP4K4/HGK with IC50s of 1.29 nM and <10 nM,respectively,in human hepaticstellate cell LX-2. TNIK&MAP4K4-IN-1 can be used for cancer and fibrosis inhibition[1].

  • CAS Number: 2478592-86-6
  • MF: C25H23FN4O3
  • MW: 446.47
  • Catalog: MAP4K
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

CDFI

CDFI is an inhibitor of the lipid II flippase MurJ. CDFI potentiates the activity of β-lactams against MRSA[1][2].

  • CAS Number: 1199797-92-6
  • MF: C28H28ClFN2
  • MW: 446.99
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ganolactone B

Ganolactone B is a lanostane-type triterpene isolated from the fruiting bodies of G. sinense[1].

  • CAS Number: 1028449-53-7
  • MF: C27H36O6
  • MW: 456.571
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 640.8±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 213.0±25.0 °C

DSPE-PEG

DSPE-PEG is a phospholipids-polymer conjugate that can be used in drug delivery applications. DSPE-PEG is a material for the formulation of nanocarriers for achieving prolonged blood circulation time, improved stability and enhanced encapsulation efficiency[1].

  • CAS Number: 145035-96-7
  • MF: C45H90NO10P
  • MW:
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(+)-trans-3'-Acetyl-4'-isobutyrylkhellactone

(+)-trans-3'-Acetyl-4'-isobutyrylkhellactone, an angular-type pyranocoumarin is a natural product that can be isolated from Peucedani Radix. [1][2].

  • CAS Number: 1562996-11-5
  • MF: C20H22O7
  • MW: 374.38
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-Octyl alcohol

3-Octanol is a fragrance ingredient. 3-octanol not to be persistent, bioaccumulative, and toxic[1].

  • CAS Number: 589-98-0
  • MF: C8H18O
  • MW: 130.228
  • Catalog: Others
  • Density: 0.8±0.1 g/cm3
  • Boiling Point: 169.0±0.0 °C at 760 mmHg
  • Melting Point: -45ºC
  • Flash Point: 65.6±0.0 °C

Fmoc-Met-OPfp

Fmoc-Met-OPfp is a Methionine (HY-13694) derivative[1].

  • CAS Number: 86060-94-8
  • MF: C26H20F5NO4S
  • MW: 537.498
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 650.6±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 347.3±31.5 °C

chlormadinon

Chlormadinone is an antiandrogen drug. Chlormadinone combined with Tamsulosin shows greater improvement in subjective symptoms of BPH[1].

  • CAS Number: 1961-77-9
  • MF: C21H27ClO3
  • MW: 362.89000
  • Catalog: Others
  • Density: 1.24 g/cm3
  • Boiling Point: 506.7ºC at 760 mmHg
  • Melting Point: 213°C
  • Flash Point: 260.2ºC

4-(ALLYLOXY)-3-METHOXYBENZALDEHYDE

O-allylvanillin is O-allylchalcone derivative with anti-cancer effects[1]. O-allylvanillin inhibits THP-1, HL60, Hep-G2, MCF-7 cells growth with IC50 values of 74.76 μM, 63.52 μM, 90.99 μM, and 90.11 μM, respectively[1].

  • CAS Number: 22280-95-1
  • MF: C11H12O3
  • MW: 192.21
  • Catalog: Others
  • Density: 1.084g/cm3
  • Boiling Point: 313.2ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 134.2ºC

Anticancer agent 101

Anticancer agent 101 is a derivative of tetracaine. Anticancer agent 101 has anti-cancer activity[1].

  • CAS Number: 2914922-80-6
  • MF: C19H20F3N3O
  • MW: 363.38
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

7-Iodo-2',3'-dideoxy-7-deaza-guanosine

7-Iodo-2',3'-dideoxy-7-deaza-guanosine is a dideoxynucleoside that can be used in DNA synthesis and sequencing reactions[1].

  • CAS Number: 114748-67-3
  • MF: C11H13IN4O3
  • MW: 376.150
  • Catalog: Others
  • Density: 2.4±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Collagen

Collagens are extracellular matrix proteins and show many applications in food, cosmetic, pharmaceutical and biomedical industries. Collagens play an important role in the structure and function of skin, cartilage, bone and connective tissue[1].

  • CAS Number: 9007-34-5
  • MF: C13H24N4O4
  • MW: 300.354
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 558.2±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 291.4±32.9 °C

DI-87

DI-87 is an orally active and selective deoxycytidine kinase (dCK) inhibitor with an EC50 of 10.2 nM. DI-87 has antitumor activity and is used in combination therapy against tumors expressing dCK[1].

  • CAS Number: 2107280-55-5
  • MF: C23H30N6O3S2
  • MW: 502.65
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2-Hydroxybenzoic acid (phenyl-13C6)

Salicylic acid-13C6 is the 13C-labeled Salicylic acid (HY-B0167). Salicylic acid is a precursor to and a metabolite of Aspirin (HY-14654), can inhibit cyclo-oxygenase-2 (COX-2) activity[1][2].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

USP1-IN-3

USP1-IN-3 is a selective USPI inhibitor. USP1-IN-3 inhibits USPI-UAFI with an IC50 value of <30 nM. USP1-IN-3 can be used for the research of cancer[1].

  • CAS Number: 2821749-58-8
  • MF: C27H24F3N7O
  • MW: 519.52
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Alpinumisoflavone

Alpinumisoflavone (compound 2) is a flavonoid derivative isolated from the stem bark of Erythrina lysistemon Hutch[1].

  • CAS Number: 34086-50-5
  • MF: C20H16O5
  • MW: 336.338
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 562.1±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 205.8±23.6 °C

Mitogenic Pentapeptide

Mitogenic Pentapeptide (Tripalmitoyl pentapeptide) is an effective activator of B lymphocyte mitogen and polyclonal. Mitogen Pentapeptide is a synthetic N-terminal analog of E. coli outer membrane lipoproteins (cysteinyl-seryl-seryl-asparaginyl-alanine). Mitogenic Pentapeptide can be used for the study of immune adjuvants[1][2].

  • CAS Number: 87173-03-3
  • MF: C67H124N6O14S
  • MW: 1269.80
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

EGR240

EGR240 is a branched-chain amino acid aminotransferase 1 (BCAT1) inhibitor. EGR240 can be used for the research of cancer, rheumatoid arthritis, and bone disease[1].

  • CAS Number: 1415683-79-2
  • MF: C7H13NaO3
  • MW: 168.17
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sodium L-lactate-1-13C solution

Lactate-13C (sodium) is the 13C labeled Lactate sodium[1]. Lactate (Lactic acid) sodium is the product of glycogenolysis and glycolysis. Lactate (Lactic acid) sodium functions in a variety of biochemical processes[2].

  • CAS Number: 81273-81-6
  • MF: C3H5NaO3
  • MW: 113.05200
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 163-165ºC(lit.)
  • Flash Point: N/A

FMOC-CYS(BZL)-OPFP

Fmoc-Cys(Bzl)-OPfp is a cysteine derivative[1].

  • CAS Number: 86060-95-9
  • MF: C31H22F5NO4S
  • MW: 599.56800
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

TNG-0746132

TNG-0746132 can be used for synthesis of the compound with anticancer activity[1].

  • CAS Number: 2821749-57-7
  • MF: C26H22F3N7O
  • MW: 505.49
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Decarine

Decarine is a alkaloid which can be isolated from Zanthoxylum simulans[1][2].

  • CAS Number: 54354-62-0
  • MF: C19H13NO4
  • MW: 319.31
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 588.0±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 309.4±28.7 °C

SERUM SPREADING FACTOR

Vitronectin is a multifunctional glycoprotein present in blood and in the extracellular matrix. Vitronectin binds glycosaminoglycans, collagen, plasminogen and the urokinase-receptor. Vitronectin also stabilizes the inhibitory conformation of plasminogen activation inhibitor-1. Vitronectin can be used for researching wound healing and in tumorprogression[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

O-benzyl-L-histidine bis(toluene-p-sulphonate)

L-Histidine benzyl ester bistosylate could play a role in the activation of HutP (an RNA-binding protein)[1].

  • CAS Number: 24593-59-7
  • MF: C27H31N3O8S2
  • MW: 589.68000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 856.1ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: N/A

L-Aspartic acid,N-[4-[[(2,4-diamino-6-pteridinyl)methyl]amino]benzoyl]-

4-Aminopteroylaspartic acid (Amino-An-Fol) inhibits the growth of psittacosis virus (6BC) in tissue cultures at concentrations which were not toxic. 4-Aminopteroylaspartic acid inhibts growth of meningopneumonitis virus in embryonated eggs or tissue culture[1].

  • CAS Number: 25312-31-6
  • MF: C18H18N8O5
  • MW: 426.38600
  • Catalog: Infection
  • Density: 1.635g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ethanone,1-(2-hydroxy-4,6-dimethoxy-3-methylphenyl)-

Methylxanthoxylin is a ketone that can be isolated from the leaves and bark of Acradenia Jianklinii.[1].

  • CAS Number: 23121-32-6
  • MF: C11H14O4
  • MW: 210.22600
  • Catalog: Others
  • Density: 1.144g/cm3
  • Boiling Point: 362.4ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 140.5ºC

AM404

AM404, an inhibitor of endocannabinoid reuptake, blocks anandamide transport with IC50 values in the low micromolar range[1]. AM404 is able to relax rat isolated hepatic arteries contracted with Phenylephrine, with a pEC50 value of 7.4 (corresponding to an EC50 of 0.04 µM). Neuroprotective Effect[2].

  • CAS Number: 183718-77-6
  • MF: C26H37NO2
  • MW: 395.578
  • Catalog: Neurological Disease
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 579.4±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 304.2±30.1 °C