TNIK&MAP4K4-IN-1

Modify Date: 2024-01-02 23:20:36

TNIK&MAP4K4-IN-1 Structure
TNIK&MAP4K4-IN-1 structure
Common Name TNIK&MAP4K4-IN-1
CAS Number 2478592-86-6 Molecular Weight 446.47
Density N/A Boiling Point N/A
Molecular Formula C25H23FN4O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TNIK&MAP4K4-IN-1


TNIK&MAP4K4-IN-1 (compound A-39) is a dual inhibitor of TNIK and MAP4K4/HGK with IC50s of 1.29 nM and <10 nM,respectively,in human hepaticstellate cell LX-2. TNIK&MAP4K4-IN-1 can be used for cancer and fibrosis inhibition[1].

 Names

Name TNIK&MAP4K4-IN-1

 TNIK&MAP4K4-IN-1 Biological Activity

Description TNIK&MAP4K4-IN-1 (compound A-39) is a dual inhibitor of TNIK and MAP4K4/HGK with IC50s of 1.29 nM and <10 nM,respectively,in human hepaticstellate cell LX-2. TNIK&MAP4K4-IN-1 can be used for cancer and fibrosis inhibition[1].
Related Catalog
Target

IC50: 1.29 nM (TNIK), <10 nM (MAP4K4/HGK)[1]

References

[1]. Aliper A, et al. TNIK and/or MAP4K4 kinase inhibitors and therapeutic uses thereof in treatment of cancer and fibrosis. World Intellectual Property Organization, WO2020170203 A1 2020-08-27.

 Chemical & Physical Properties

Molecular Formula C25H23FN4O3
Molecular Weight 446.47
Top Suppliers:I want be here

No recommended suppliers.

Hot Compounds More...
Dichloromethane
CAS#:75-09-2
Polyacrylic acid
CAS#:9003-01-4
sodium carbonate
CAS#:497-19-8
Silicon dioxide
CAS#:7631-86-9
Triethanolamine
CAS#:102-71-6
Demeton
CAS#:126-75-0
Water
CAS#:7732-18-5
4-(4-Piperidinyl)morpholine dihydrochloride
CAS#:53617-35-9
Diclofenac sodium
CAS#:15307-79-6
Budesonide
CAS#:51372-29-3