Chemsrc provides Others's classification. They are divided into Androgen Receptor, Aromatase, Estrogen Receptor/ERR, Progesterone Receptor, Thyroid Hormone Receptor, Others according to their Biological activity.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

3-(4-Hydroxy-3,5-dimethoxyphenyl)-1,2-propanediol

3-(4-hydroxy-3,5-dimethoxyphenyl)-1,2-propanediol (Compound 8) is a phenolic glucoside.3-(4-hydroxy-3,5-dimethoxyphenyl)-1,2-propanediol is isolated from the stems of natural Xylosma controversum[1].

  • CAS Number: 22805-15-8
  • MF: C11H16O5
  • MW: 228.24
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 444.3±40.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 222.5±27.3 °C

BI 135585

BI-135585 is a potent, selective and orally active 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibitor with an IC50 of 13 nM. BI-135585 exhibits >1000-fold selectivity over other hydroxysteroid dehydrogenases. BI-135585 can be used for type 2 diabetes research[1][2].

  • CAS Number: 1114561-85-1
  • MF: C28H32N2O4
  • MW: 460.565
  • Catalog: Metabolic Disease
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 703.6±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 379.3±32.9 °C

Spiramine A

Spiramine A (Spiramine C acetate (ester)) is a diterpene alkaloid with antitumor and antimicrobial activity. Spiramine A inhibits PAF-induced rabbit platelet aggregation in a concentration-dependent manner, with an IC50 vallue of 6.7 μM[1].

  • CAS Number: 114531-28-1
  • MF: C24H33NO4
  • MW: 399.523
  • Catalog: Cancer
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Monoethyl fumarate

Monoethyl fumarate is the monoethyl ester form of fumaric acid. Monoethyl fumarate is a kind of effective preservative and polymerization agent for macromolecular material[1].

  • CAS Number: 2459-05-4
  • MF: C6H8O4
  • MW: 144.125
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 147 ºC (16 mmHg)
  • Melting Point: 64-69 ºC
  • Flash Point: 109.6±16.1 °C

Serinol-d5

Serinol-d5 is the deuterium labeled Serino[1].

  • CAS Number: 2708287-37-8
  • MF: C3H4D5NO2
  • MW: 96.14
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

RASP-IN-1

RASP-IN-1 (compound A) is a lipophili ccompound used for macular degeneration inhibition. RASP-IN-1 is biologically active in the retina of the rabbit's eye. Thirty minutes after IP treatment with 14C-RASP-IN-1 (10 mg/kg),the Cmax amount of 14C-RASP-IN-1 in the posterior eye cup is 14.36 μg/g in mice model[1].

  • CAS Number: 916056-81-0
  • MF: C16H16N2O2
  • MW: 268.31
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

ANAKINRA

Anakinra is a recombinant, nonglycosylated human interleukin-1 receptor (IL-1R) antagonist. Anakinra is the first biological agent to block the pro-inflammatory effects[1][2].

  • CAS Number: 143090-92-0
  • MF: C759H1186N208O232S10
  • MW: 509.556
  • Catalog: Cancer
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-NITRO-DL-PHENYLALANINE HYDRATE

4-Nitro-DL-phenylalanine Hydrate is a phenylalanine derivative[1].

  • CAS Number: 207569-25-3
  • MF: C9H12N2O5
  • MW: 228.202
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 230 °C(dec.)
  • Flash Point: N/A

AIMP2-DX2-IN-1

AIMP2-DX2-IN-1 (Compound 35) is a potent AIMP2-DX2 inhibitor with an IC50 of 0.1063 μM[1].

  • CAS Number: 848256-17-7
  • MF: C23H21NO3
  • MW: 359.42
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2-Aminopurine dihydrochloride

2-Aminopurine dihydrochloride is a fluorescent analog of guanosine. 2-Aminopurine dihydrochloride can be used as a fluorescence probe for nucleic acid structure and dynamics. Incorporating 2-Aminopurine dihydrochloride into DNA quenches its fluorescence[1][2].

  • CAS Number: 1428126-74-2
  • MF: C5H7Cl2N5
  • MW: 208.049
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Diethylamine-d6-hydrochloride

Diethylamine-d6-hydrochloride is the deuterium labeled Diethylamine hydrochloride[1].

  • CAS Number: 1219805-68-1
  • MF: C4H6D6ClN
  • MW: 115.63
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

delta-2-carene

4497-92-1

  • CAS Number: 4497-92-1
  • MF: C10H16
  • MW: 136.23400
  • Catalog: Cancer
  • Density: 0.879g/cm3
  • Boiling Point: 167.5ºC at 760mmHg
  • Melting Point: 25°C (estimate)
  • Flash Point: 38.3ºC

3-Pyridinecarboxylicacid, 6,6'-dithiobis-

6,6′-Dithiodinicotinic acid is a sulfur-containing organic compound belonging to nicotinic acid derivatives, which can be used as a specific sulfhydryl blocker[1].

  • CAS Number: 15658-35-2
  • MF: C12H8N2O4S2
  • MW: 308.33
  • Catalog: Others
  • Density: 1.66g/cm3
  • Boiling Point: 584.2ºC at 760mmHg
  • Melting Point: 263-265 °C(lit.)
  • Flash Point: 307.1ºC

(D-Trp6)-LHRH (2-10) trifluoroacetate salt

(D-Trp6)-LHRH (2-10) is a biologically active peptide.

  • CAS Number: 108787-46-8
  • MF: C59H77N17O11
  • MW: 1200.350
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

manassantin B

Manassantin B (compound 6) is a kind of lignan. Manassantin B can be isolated from the ethyl acetate extract of the roots of Saururus chinensis. Manassantin B has cytotoxicities against HT-29 with an IC50 value of 12 μM[1].

  • CAS Number: 88497-88-5
  • MF: C41H48O11
  • MW: 716.81300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

C12 NBD Galactosylceramide (d18:1/12:0)

C12 NBD galactosylceramide, fluorescent dye, is a biologically active derivative of galactosylceramide that is tagged with a fluorescent C12 nitrobenzoxadiazole (C12 NBD) group. C12 NBD galactosylceramide can be used for the research of imaging[1].

  • CAS Number: 474942-98-8
  • MF: C42H71N5O11
  • MW: 822.040
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3,4',5-Trichloro-1,1'-biphenyl-d4

3,4',5-Trichloro-1,1'-biphenyl-d4 is the deuterium labeled 3,4',5-Trichloro-1,1'-biphenyl[1].

  • CAS Number: 1276197-48-8
  • MF: C12H3D4Cl3
  • MW: 261.57
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Picroside III

Picroside III is an iridoid glycoside isolated from Picrorhiza scrophulariiflora (PS), a traditional Chinese medicine[1].

  • CAS Number: 64461-95-6
  • MF: C25H30O13
  • MW: 538.498
  • Catalog: Inflammation/Immunology
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 791.2±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 266.9±26.4 °C

Carboprost

Carboprost (15(S)-15-Methyl Prostaglandin F2α) is a metabolically stable synthetic analog of prostaglandin F2α. Carboprost stimulates uterine contractions and induces abortion. Carboprost is used for postpartum hemorrhage due to uterine atony and for the termination of pregnancy in the second trimester[1][2].

  • CAS Number: 35700-23-3
  • MF: C21H36O5
  • MW: 368.508
  • Catalog: Endocrinology
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 536.6±50.0 °C at 760 mmHg
  • Melting Point: 79-82ºC
  • Flash Point: 292.4±26.6 °C

Octylbenzene-d5

Octylbenzene-d5 is the deuterium labeled Octylbenzene[1].

  • CAS Number: 1219799-23-1
  • MF: C14H17D5
  • MW: 195.36
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

6-Carboxyfluorescein Diacetate

6-CFDA is fluorescent polyanionic probe, and its derivatives such as 2′,7′-bis (2-carboxyethyl)-5(6)-carboxyfluorescein are used to measure changes in intracellular pH (pHi) and processes such as dendrimer aggregation and absorption.

  • CAS Number: 3348-03-6
  • MF: C25H16O9
  • MW: 460.389
  • Catalog: Dye Reagents
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 701.6±60.0 °C at 760 mmHg
  • Melting Point: 152–153°C
  • Flash Point: 245.1±26.4 °C

RuBPS

Tetrasodium,4-(1,10-phenanthrolin-4-yl)benzenesulfonate,ruthenium((II)) is a luminescent indicator dye[1].

  • CAS Number: 301206-84-8
  • MF: C72H42N6Na4O18RuS6
  • MW: 1664.55000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

celangulin XIX

Celangulin XIX is a insecticidal that can be isolated from Celastrus angulatu. Celangulin XIX has strong insecticidal activity against Mythimna separate with an ED50 of 73.3 μg/g[1].

  • CAS Number: 403505-80-6
  • MF: C35H42O14
  • MW: 686.7
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Abz-FRK(Dnp)-P

Abz-FR-K(Dnp)-P-OH is an angiotensin I-converting enzyme (ACE) substrate and an internally quenched fluorogenic substrate for real time fluorescent assay[1].

  • CAS Number: 500799-61-1
  • MF: C39H49N11O10
  • MW: 831.874
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Glyoxalase I inhibitor

Glyoxalase I inhibitor is a potent Glyoxalase I inhibitor, candidate for anticancer agents.

  • CAS Number: 221174-33-0
  • MF: C21H30BrClN4O8S
  • MW: 613.90700
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Hydroxocobalamin monohydrochloride

Hydroxocobalamin hydrochloride (Vitamin B12a hydrochloride) is a naturally occurring vitamin B12 form found in food and used as a dietary supplement in the treatment of vitamin B12 deficiency.

  • CAS Number: 59461-30-2
  • MF: C62H89ClCoN13O15P
  • MW: 1381.81
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

WAY-354436

WAY-354436 is an active molecule.

  • CAS Number: 850023-52-8
  • MF: C19H22FN3S
  • MW: 343.46
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sperm motility agonist-2

Sperm motility agonist-2 (compound 797) is a Sperm motility agonist. Sperm motility agonist-2 can be used in studies of infertility and enhancement of fertility[1].

  • CAS Number: 926079-67-6
  • MF: C16H15ClN2O2S
  • MW: 334.82
  • Catalog: Endocrinology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

clofibride

Clofibride is an orally active hypolipaemic agent of pchlorophenoxyisobutyric type. Clofibride has weak toxicity and marked hypocholesterolaemic and hypotriglyceridaemic activity. Clofibride is converted into 4-chlorophenoxyisobutyric acid (CPIB) and 4-hydroxy-N-dimethylbutyramide (HMB) in vivo[1].

  • CAS Number: 26717-47-5
  • MF: C16H22ClNO4
  • MW: 327.80300
  • Catalog: Metabolic Disease
  • Density: 1.163g/cm3
  • Boiling Point: 448.7ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 225.2ºC

Iopentol

Iopentol is a non-ionic, intravascular contrast media[1].

  • CAS Number: 89797-00-2
  • MF: C20H28I3N3O9
  • MW: 835.16
  • Catalog: Others
  • Density: 2.095g/cm3
  • Boiling Point: 858.8ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 473.2ºC