Iopentol

Modify Date: 2024-01-06 11:53:07

Iopentol structure	Common Name	Iopentol
	CAS Number	89797-00-2	Molecular Weight	835.16
	Density	2.095g/cm3	Boiling Point	858.8ºC at 760 mmHg
	Molecular Formula	C₂₀H₂₈I₃N₃O₉	Melting Point	N/A
	MSDS	N/A	Flash Point	473.2ºC

Use of Iopentol

Iopentol is a non-ionic, intravascular contrast media[1].

Name	5-[acetyl-(2-hydroxy-3-methoxypropyl)amino]-1-N,3-N-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide
Synonym	More Synonyms

Description	Iopentol is a non-ionic, intravascular contrast media[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Aulie Michelet A. Effects of intravascular contrast media on blood-brain barrier. Comparison between iothalamate, iohexol, iopentol and iodixanol. Acta Radiol. 1987 May-Jun;28(3):329-33.

Density	2.095g/cm3
Boiling Point	858.8ºC at 760 mmHg
Molecular Formula	C₂₀H₂₈I₃N₃O₉
Molecular Weight	835.16
Flash Point	473.2ºC
Exact Mass	834.89600
PSA	195.87000
LogP	0.17620
Index of Refraction	1.693

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CZ2211000

CHEMICAL NAME :: 1,3-Benzenedicarboxamide, 5-(acetyl(2-hydroxy-3-methoxypropyl)amino)-N,N'-bis (2,3-dihydroxypropyl)-2,4,6-triiodo-

CAS REGISTRY NUMBER :: 89797-00-2

LAST UPDATED :: 199509

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C20-H28-I3-N3-O9

MOLECULAR WEIGHT :: 835.21

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 22573 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARASA5 Acta Radiologica, Supplementum. (Acta Radiologica, POB 7449, S-10391 Stockholm, Sweden) No.1- 1921- Volume(issue)/page/year: 370,41,1987

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 42517 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARASA5 Acta Radiologica, Supplementum. (Acta Radiologica, POB 7449, S-10391 Stockholm, Sweden) No.1- 1921- Volume(issue)/page/year: 370,41,1987 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Primate - monkey

DOSE/DURATION :: 553 gm/kg/28D-I

TOXIC EFFECTS :: Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Endocrine - changes in thyroid weight

REFERENCE :: ARASA5 Acta Radiologica, Supplementum. (Acta Radiologica, POB 7449, S-10391 Stockholm, Sweden) No.1- 1921- Volume(issue)/page/year: 370,45,1987

RIDADR	NONH for all modes of transport

Value of single-dose contrast-enhanced magnetic resonance angiography versus intraarterial digital subtraction angiography in therapy indications in abdominal and iliac arteries.

Cardiovasc. Intervent. Radiol. 30(3) , 376-82, (2007)

The objective of the study was to prove the value of single-dose contrast-enhanced magnetic resonance angiography [three-dimensional (3D) ceMRA] in abdominal and iliac arteries versus the reference st...

[Determination of the distribution volume of contrast media solutions injected intrahepatically: pre-pilot studies for intratumoral gene therapy].

Rofo. 174(3) , 357-62, (2002)

Determination of the intrahepatic distribution volume of two contrast media (CM) by CT-guided application in an ex-vivo and an in-vivo model (pig liver).In pig livers ex-vivo and in-vivo, 131 CT-guide...

Influence of two non-ionic radiographic contrast media with different osmolalities on coagulation in invasive cardiology. A prospective, randomised comparative study.

Acta radiol. 43(6) , 617-22, (2002)

To investigate the influence of two non-ionic radiographic contrast media with different osmolality on thrombocytic function and the plasmatic coagulation system.The study was carried out as a randomi...

IOPENTOL

UNII-7D6XWX076T

Iopentolum

Imagopaque

Dichloromethane
CAS#:75-09-2

Polyacrylic acid
CAS#:9003-01-4

sodium carbonate
CAS#:497-19-8

Silicon dioxide
CAS#:7631-86-9

Triethanolamine
CAS#:102-71-6

Demeton
CAS#:126-75-0

Water
CAS#:7732-18-5

4-(4-Piperidinyl)morpholine dihydrochloride
CAS#:53617-35-9

Diclofenac sodium
CAS#:15307-79-6

Budesonide
CAS#:51372-29-3

Iopentol

Use of Iopentol

Names

Iopentol Biological Activity

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Safety Information

Articles25

Synonyms