Iopentol
Names
[ CAS No. ]:
89797-00-2
[ Name ]:
Iopentol
[Synonym ]:
IOPENTOL
UNII-7D6XWX076T
Iopentolum
Imagopaque
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
2.095g/cm3
[ Boiling Point ]:
858.8ºC at 760 mmHg
[ Molecular Formula ]:
C20H28I3N3O9
[ Molecular Weight ]:
835.16
[ Flash Point ]:
473.2ºC
[ Exact Mass ]:
834.89600
[ PSA ]:
195.87000
[ LogP ]:
0.17620
[ Index of Refraction ]:
1.693
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CZ2211000
- CHEMICAL NAME :
- 1,3-Benzenedicarboxamide, 5-(acetyl(2-hydroxy-3-methoxypropyl)amino)-N,N'-bis (2,3-dihydroxypropyl)-2,4,6-triiodo-
- CAS REGISTRY NUMBER :
- 89797-00-2
- LAST UPDATED :
- 199509
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C20-H28-I3-N3-O9
- MOLECULAR WEIGHT :
- 835.21
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 22573 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARASA5 Acta Radiologica, Supplementum. (Acta Radiologica, POB 7449, S-10391 Stockholm, Sweden) No.1- 1921- Volume(issue)/page/year: 370,41,1987
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 42517 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARASA5 Acta Radiologica, Supplementum. (Acta Radiologica, POB 7449, S-10391 Stockholm, Sweden) No.1- 1921- Volume(issue)/page/year: 370,41,1987 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Primate - monkey
- DOSE/DURATION :
- 553 gm/kg/28D-I
- TOXIC EFFECTS :
- Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Endocrine - changes in thyroid weight
- REFERENCE :
- ARASA5 Acta Radiologica, Supplementum. (Acta Radiologica, POB 7449, S-10391 Stockholm, Sweden) No.1- 1921- Volume(issue)/page/year: 370,45,1987
Safety Information
[ RIDADR ]:
NONH for all modes of transport
Articles
Cardiovasc. Intervent. Radiol. 30(3) , 376-82, (2007)
The objective of the study was to prove the value of single-dose contrast-enhanced magnetic resonance angiography [three-dimensional (3D) ceMRA] in abdominal and iliac arteries versus the reference st...
[Determination of the distribution volume of contrast media solutions injected intrahepatically: pre-pilot studies for intratumoral gene therapy].Rofo. 174(3) , 357-62, (2002)
Determination of the intrahepatic distribution volume of two contrast media (CM) by CT-guided application in an ex-vivo and an in-vivo model (pig liver).In pig livers ex-vivo and in-vivo, 131 CT-guide...
Influence of two non-ionic radiographic contrast media with different osmolalities on coagulation in invasive cardiology. A prospective, randomised comparative study.Acta radiol. 43(6) , 617-22, (2002)
To investigate the influence of two non-ionic radiographic contrast media with different osmolality on thrombocytic function and the plasmatic coagulation system.The study was carried out as a randomi...