Name | carboprost |
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Synonyms |
prostin15m
Methyl-pgf2a (15S)-15-Methylprostaglandin F2α (E,Z)-(1R,2R,3R,5S)-7-(3,5-Dihydroxy-2-((3S)-(3-hydroxy-3-methyl-1-octenyl))cyclopentyl)-5-heptenoic acid 15s)-13e 15-Methyl-PGF2a Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-15-methyl-, (5Z,9α,11α,13E,15S)- 15-ME-PGF2a methyldinoprost (5Z,9a,11a,13E,15S)-9,11,15-Trihydroxy-15-methylprosta-5,13-dien-1-oic Acid (15S)-15-Methyl-PGF2a Carboprost (15S)-15-Methyl PGF2a (15S)-15-Methylprostaglandin F2a 15-methyl-15S-PGF2α (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxy-15-methylprosta-5,13-dien-1-oic acid MFCD00135249 |
Description | Carboprost (15(S)-15-Methyl Prostaglandin F2α) is a metabolically stable synthetic analog of prostaglandin F2α. Carboprost stimulates uterine contractions and induces abortion. Carboprost is used for postpartum hemorrhage due to uterine atony and for the termination of pregnancy in the second trimester[1][2]. |
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Related Catalog | |
In Vivo | The methyl ester of Carboprost (15(S)-15-Methyl Prostaglandin F2α; 15M-PGF2 alpha, 12.5 mg/monkey) loweres serum progesterone to 12% of pretreatment values within 24 hours, however progesterone returnes to normal limits within 48 hours[1]. |
References |
Density | 1.1±0.1 g/cm3 |
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Boiling Point | 536.6±50.0 °C at 760 mmHg |
Melting Point | 79-82ºC |
Molecular Formula | C21H36O5 |
Molecular Weight | 368.508 |
Flash Point | 292.4±26.6 °C |
Exact Mass | 368.256287 |
PSA | 97.99000 |
LogP | 2.49 |
Vapour Pressure | 0.0±3.2 mmHg at 25°C |
Index of Refraction | 1.565 |
Storage condition | -20°C Freezer, Under Inert Atmosphere |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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Hazard Codes | Xi |
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Risk Phrases | R36:Irritating to the eyes. |
Safety Phrases | S26-S37/39 |
WGK Germany | 2 |
RTECS | TU0175000 |
Precursor 4 | |
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DownStream 1 | |