Monoethyl fumarate

Modify Date: 2024-01-04 23:18:42

Monoethyl fumarate Structure
Monoethyl fumarate structure
Common Name Monoethyl fumarate
CAS Number 2459-05-4 Molecular Weight 144.125
Density 1.2±0.1 g/cm3 Boiling Point 147 ºC (16 mmHg)
Molecular Formula C6H8O4 Melting Point 64-69 ºC
MSDS Chinese USA Flash Point 109.6±16.1 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of Monoethyl fumarate


Monoethyl fumarate is the monoethyl ester form of fumaric acid. Monoethyl fumarate is a kind of effective preservative and polymerization agent for macromolecular material[1].

 Names

Name Monoethyl fumarate
Synonym More Synonyms

 Monoethyl fumarate Biological Activity

Description Monoethyl fumarate is the monoethyl ester form of fumaric acid. Monoethyl fumarate is a kind of effective preservative and polymerization agent for macromolecular material[1].
Related Catalog
References

[1]. Ausama Atwan, et al. Oral Fumaric Acid Esters for Psoriasis. Cochrane Database Syst Rev. 2015 Aug 10;2015(8):CD010497.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 147 ºC (16 mmHg)
Melting Point 64-69 ºC
Molecular Formula C6H8O4
Molecular Weight 144.125
Flash Point 109.6±16.1 °C
Exact Mass 144.042252
PSA 63.60000
LogP 0.29
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.469
Storage condition Refrigerator

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 1
HS Code 2918990090

 Synthetic Route

 Customs

HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles28

More Articles
Structure-activity relationships of trans-substituted-propenoic acid derivatives on the nicotinic acid receptor HCA2 (GPR109A).

Bioorg. Med. Chem. Lett. 21 , 2736-9, (2011)

Nicotinic acid (niacin) has been used for decades as an antidyslipidemic drug in man. Its main target is the hydroxy-carboxylic acid receptor HCA2 (GPR109A), a G protein-coupled receptor. Other acids ...

Fumarate analogs act as allosteric inhibitors of the human mitochondrial NAD(P)+-dependent malic enzyme.

PLoS ONE 9(6) , e98385, (2014)

Human mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME) is allosterically activated by the four-carbon trans dicarboxylic acid, fumarate. Previous studies have suggested that the dicarboxylic...

The use of differential transverse relaxation to detect mobile species in solids.

Solid State Nucl. Magn. Reson. 6(1) , 63-71, (1996)

Delayed acquisition of the proton NMR in selected organic molecular solids (L-alanine, durene, ethyl fumarate, and p-hydroxybenzoic acid) is shown to allow the observation of mobile species in the pre...

 Synonyms

Ethyl fumaric acid
2-Butenedioic acid, monoethyl ester, (2E)-
ETHYL ACID FUMARATE
Fumaric acid monoethyl ester
Monoethyl FuMerate
Ethyl fumarate
mono-Ethyl Fumarate
(2E)-4-Ethoxy-4-oxo-2-butenoic acid
RARECHEM AL BE 1505
Ethyl Hydrogen Fumarate
FuMaric Acid Ethyl Ester
Ethylfumarat
(2E)-4-ethoxy-4-oxobut-2-enoic acid
EINECS 219-544-7
Monoethyl FuMarate
monoethyl fumaric acid
MFCD00002699
(E)-4-Ethoxy-4-oxobut-2-enoic acid
ETHYL FUMARATE MONOESTER
Quetiapine Impurity 33
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