ethyl acetate

Modify Date: 2025-08-20 11:06:41

ethyl acetate structure	Common Name	ethyl acetate
	CAS Number	141-78-6	Molecular Weight	88.105
	Density	0.9±0.1 g/cm3	Boiling Point	73.9±3.0 °C at 760 mmHg
	Molecular Formula	C₄H₈O₂	Melting Point	−84 °C(lit.)
	MSDS	Chinese USA	Flash Point	-3.3±0.0 °C
	Symbol	GHS02, GHS07	Signal Word	Danger

Name	ethyl acetate
Synonym	More Synonyms

Density	0.9±0.1 g/cm3
Boiling Point	73.9±3.0 °C at 760 mmHg
Melting Point	−84 °C(lit.)
Molecular Formula	C₄H₈O₂
Molecular Weight	88.105
Flash Point	-3.3±0.0 °C
Exact Mass	88.052429
PSA	26.30000
LogP	0.71
Vapour density	3 (20 °C, vs air)
Vapour Pressure	111.7±0.1 mmHg at 25°C
Index of Refraction	1.373
Storage condition	2-8°C
Stability	Stable. Incompatible with various plastics, strong oxidizing agents. Highly flammable. Vapour/air mixtures explosive. May be moisture sensitive.
Water Solubility	80 g/L (20 ºC)

ethyl acetate MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AH5425000

CHEMICAL NAME :: Acetic acid, ethyl ester

CAS REGISTRY NUMBER :: 141-78-6

LAST UPDATED :: 199712

DATA ITEMS CITED :: 54

MOLECULAR FORMULA :: C4-H8-O2

MOLECULAR WEIGHT :: 88.12

WISWESSER LINE NOTATION :: 2OV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Human

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Human

DOSE/DURATION :: 400 ppm

TOXIC EFFECTS :: Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Sense Organs and Special Senses (Eye) - conjunctive irritation Lungs, Thorax, or Respiration - other changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5620 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 200 gm/m3

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - acute pulmonary edema Gastrointestinal - changes in structure or function of salivary glands

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4100 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - changes in motor activity (specific assay) Behavioral - coma

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 45 gm/m3/2H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 709 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 61 gm/m3

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 3 gm/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Gastrointestinal - nausea or vomiting Blood - other changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 4935 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >20 mL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 5500 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - changes in motor activity (specific assay) Behavioral - coma

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 3 gm/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 8 mL/kg/8D-I

TOXIC EFFECTS :: Liver - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases Biochemical - Metabolism (Intermediary) - other carbohydrates

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Rodent - hamster Fibroblast

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 22,623,1984 *** REVIEWS *** ACGIH TLV-Not classifiable as a human carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 1440 mg/m3 (400 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 TOXICOLOGY REVIEW AMIHAB AMA Archives of Industrial Health. (Chicago, IL) V.11-21, 1955-60. For publisher information, see AEHLAU. Volume(issue)/page/year: 21,28,1960 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 MSHA STANDARD-air:TWA 400 ppm (1400 mg/m3) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,102,1971 OSHA PEL (Gen Indu):8H TWA 400 ppm (1400 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 400 ppm (1400 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 400 ppm (1400 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 400 ppm (1400 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 400 ppm (1400 mg/m3) JAN 1993 OEL-BELGIUM:TWA 400 ppm (1440 mg/m3) JAN 1993 OEL-DENMARK:TWA 300 ppm (1100 mg/m3) JAN 1993 OEL-FINLAND:TWA 300 ppm (1100 mg/m3);STEL 500 ppm (1800 mg/m3) JAN 1993 OEL-FRANCE:TWA 400 ppm (1400 mg/m3) JAN 1993 OEL-GERMANY:TWA 400 ppm (1400 mg/m3) JAN 1993 OEL-HUNGARY:TWA 400 mg/m3;STEL 1200 mg/m3 JAN 1993 OEL-JAPAN:TWA 400 ppm (1400 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 400 ppm (1400 mg/m3) JAN 1993 OEL-THE PHILIPPINES:TWA 400 ppm (1400 mg/m3) JAN 1993 OEL-POLAND:TWA 200 ppm JAN 1993 OEL-RUSSIA:TWA 400 ppm;STEL 200 mg/m3 JAN 1993 OEL-SWEDEN:TWA 150 ppm (500 mg/m3);STEL 300 ppm (1100 mg/m3) JAN 1993 OEL-SWITZERLAND:TWA 400 ppm (1400 mg/m3);STEL 800 ppm JAN 1993 OEL-TURKEY:TWA 400 ppm (1400 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 400 ppm (1400 mg/m3) JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO ETHYL ACETATE-air:10H TWA 400 ppm REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 31470 No. of Facilities: 37072 (estimated) No. of Industries: 234 No. of Occupations: 152 No. of Employees: 407816 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 31470 No. of Facilities: 40728 (estimated) No. of Industries: 234 No. of Occupations: 154 No. of Employees: 504448 (estimated) No. of Female Employees: 119505 (estimated)

Symbol	GHS02, GHS07
Signal Word	Danger
Hazard Statements	H225-H319-H336
Supplemental HS	Repeated exposure may cause skin dryness or cracking.
Precautionary Statements	P210-P261-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	F:Flammable
Risk Phrases	R11;R36;R66;R67
Safety Phrases	S16-S26-S33-S36/37-S45-S7
RIDADR	UN 1173 3/PG 2
WGK Germany	1
RTECS	AH5425000
Packaging Group	II
Hazard Class	3
HS Code	2915310000

Precursor 10
CAS#:64-17-5 Ethanol CAS#:64-19-7 acetic acid CAS#:75-07-0 ch3cho CAS#:54509-73-8 ethene
CAS#:79-20-9 Methyl acetate CAS#:201230-82-2 carbon monoxide CAS#:105-36-2 ethyl 2-bromoacetate CAS#:108-05-4 vinyl acetate
CAS#:5419-55-6 Triisopropylborate CAS#:67-56-1 Methanol
DownStream 10
CAS#:104556-86-7 Ethyl 4,7-dihyd... CAS#:109839-21-6 3-phenylhexane-... CAS#:3318-61-4 1-Phenyl-2,4-pe... CAS#:106276-48-6 3-(2-methoxynap...
CAS#:1060806-62-3 6-Bromo-2-metho... CAS#:1070-14-0 1,4-Hexadien-3-ol CAS#:100718-97-6 ethyl 4-benzami... CAS#:606-23-5 1,3-INDANDIONE
CAS#:562-90-3 Silicon tetraacetate CAS#:4316-23-8 4-Methylphthali...

HS Code	2915390090
Summary	2915390090. esters of acetic acid. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:5.5%. General tariff:30.0%

Glucose and glycerol concentrations and their tracer enrichment measurements using liquid chromatography tandem mass spectrometry.

J. Mass Spectrom. 49(10) , 980-8, (2014)

The present study describes a new liquid chromatography tandem mass spectrometry method for high-throughput quantification of glucose and glycerol in human plasma using stable isotopically labeled int...

Phaleria macrocarpa Boerl. (Thymelaeaceae) leaves increase SR-BI expression and reduce cholesterol levels in rats fed a high cholesterol diet.

Molecules 20(3) , 4410-29, (2015)

In vitro and in vivo studies of the activity of Phaleria macrocarpa Boerl (Thymelaeaceae) leaves against the therapeutic target for hypercholesterolemia were done using the HDL receptor (SR-BI) and hy...

Effect of germinated brown rice extracts on pancreatic lipase, adipogenesis and lipolysis in 3T3-L1 adipocytes.

Lipids Health Dis. 13 , 169, (2014)

This study investigated anti-obesity effects of seven different solvent (n-hexane, toluene, dicholoromethane, ethyl acetate, absolute methanol, 80% methanol and deionized water) extracts of germinated...

Ethyl ethanoate

Acetidin

Ethylacetate

EINECS 205-500-4

Vinegar naphtha

Ethyl acetic ester

MFCD00003568

Ethyl acetate

Acetic ether

Acetic acid ethyl ester

Acetoxyethane

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: ethyl acetate
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: ethyl acetate
Price: ￥188.0/100ml ￥328.0/500ml ￥528.0/1l ￥588.0/4l
Purity: 98.0%
Delivery: Inquiry
Contact: Liu jia
Email: 2130147988@qq.com

Get all suppliers and price by the below link:

ethyl acetate suppliers

ethyl acetate price

ethyl acetate

Names

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Safety Information

Synthetic Route

Precursor & DownStream

Customs

Articles863

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.