14-Deoxycoleon U is a natural abietane-type diterpene. 14-Deoxycoleon U exerts an inhibitory effect on tumor cells proliferation. 14-Deoxycoleon U may be a potent anti-cancerous lead compound for lung cancer research[1].
LY 222306 is a glycinamide ribonucleotide formyltransferase (GARFT) inhibitor with a Ki of 0.77 nM.
Monohydroxy Netupitant is the metabolite of Netupitant, which is a highly selective NK1 receptor antagonist.
2,3,6-Trichlorophenol-d2 is the deuterium labeled 2,3,6-Trichlorophenol[1].
TOK-8801 is a synthesized dihydroimidazothiazole carboxamide and is under development as an immunomodulator.
5,6-Epoxyergosterol is a natural product that can be isolated from endophytic fungus Phyllosticta capitalensis[1].
4-(Benzo[d]oxazol-2-yl)aniline is a potent antitumor agent. 4-(Benzo[d]oxazol-2-yl)aniline has inhibitory activity against mammary carcinoma cell lines[1].
Athidathion(GS-13006) is an organophosphate insecticide.
S-(5′-Adenosyl)-L-cysteine is a cysteine derivative[1].
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Sprengerinin is a potential angiogenesis inhibitor. Sprengerinin exerts anti-tumorigenic effects in vitro[1].
Solasurine is a steroidal alkaloid that can be isolated from Solanum surrattence. Solasurine can interact with the C3-like protease (SARS-CoV-2 main protease) amino acids Phe8, Pro9, Ile152, Tyr154, Pro293, Phe294, Val297, and Arg298[1].
VIT-2763, an oral ferroportin inhibitor, inhibits hepcidin binding to ferroportin and blocks iron efflux. VIT-2763 has the potential in the treatment of β-thalassemia[1].
C6 NBD Phytoceramide is a fluorescently labeled short-chain ceramide analog that can be recognized by mammalian GlcCer synthase (GCS)[1].
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2,4-difluoro-D-phenylalanine is a phenylalanine derivative[1].
6-Benzylaminopurine-d5 (Benzyladenine-d5) is the deuterium labeled 6-Benzylaminopurine. 6-Benzylaminopurine is a cytokinin[1].
α-Tocopherol (vitamin E phosphate) is the compound demonstrating the highest vitamin E activity, which is available both in its natural form as RRR-alpha-tocopherol isolated from plant sources.
1-Ethyl-3-methylbenzene-d5 is the deuterium labeled 1-Ethyl-3-methylbenzene[1].
PKG drug G1 targets C42 of PKG Iα. PKG drug G1 can couple to vasodilation and blood pressure lowering by a C42 PKG Iα-independent mechanism.
15:0 Lyso PG-d5 is deuterium labeled 15:0 Lyso PG.
H-D-2-Nal-OH is an alanine derivative[1].
L-Tyrosine β-naphthylamide is a tyrosine derivative[1].
N3-Gly-Gly-OH is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1].
Pachysamine M (Compound 5) is a pregnane alkaloid.Pachysamine M is isolated from naturalPachysandra terminalisSieb. et Zucc[1].
KTX-582 intermediate-3 is an intermediate in the synthesis of KTX-582 (HY-148274) and can be used for ADC preparation. KTX-582 is an IRAK4 degrader and inducer of apoptosis with DC50 of 4 nM and 5 nM for IRAK4 and Ikaros, respectively[1].
Ro 08-2750 is a non-peptide and reversible nerve growth factor (NGF) inhibitor which binds to NGF, and with an IC50 of ~ 1 µM. Ro 08-2750 inhibits NGF binding to p75NTR selectively over TRKA[1].
Pirimicarb-d6 is the deuterium labeled Diuron. Diuron is a phenylurea herbicide that inhibits photosynthesis by preventing the formation of ATP and NADH. Diuron (2,500 ppm, dietary) increases the incidence of urinary bladder urothelial carcinomas in male
AA 497 is a bronchodilator[1].
UMB68 sodium is a selective GHB receptor ligand. UMB68 sodium displaces [3H]NCS-382 with an IC50 of 38 nM in rat cerebrocortical membranes. UMB68 sodium has no significant affinity at GABAB receptors, cannot be metabolized to GABA-active compounds[1].
Porphyra 334 is an antioxidative and anti-photoaging agent. Porphyra 334 suppresses ROS production and the expression of MMPs following UVA irradiation[1][2].