2140-79-6

2140-79-6 structure

Name: 2'-O-Methyladenosine
Chemical Name: cordysinin B
CAS Number: 2140-79-6
Molecular Formula: C₁₁H₁₅N₅O₄
Molecular Weight: 281.268
Catalog: Biochemical Nucleoside drugs Nucleoside intermediate
Create Date: 2018-04-20 08:00:00
Modify Date: 2024-01-02 22:47:55
2'-O-Methyladenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2'-O-Methyladenosine exhibits unique hypotensive activities [1][2].

Name	cordysinin B
Synonyms	UNII-02YX82IHZ5 2'-O-Methyl adenosine 2'-methyl-adenosine 2'-O-methylAdo 2′-O-Methyladenosine (2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)-4-methoxyoxolan-3-ol 2'-methoxyadenosine 2'-OMeAdenosine MFCD00056002 Adenosine, 2'-O-methyl- 2'-O-Methyladenosine 2'-O-Methyl-D-adenosine (2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol Adenosine,2'-O-methyl

Description	2'-O-Methyladenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2'-O-Methyladenosine exhibits unique hypotensive activities [1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others
In Vivo	2'-O-Methyladenosine (100, 200 mg/kg, ip, single dose) exhibits unique hypotensive activities in rats[2]. Animal Model: Male spontaneously hypertensive rats (SHR; 16 weeks old)[2]. Dosage: 100, 200 mg/kg. Administration: IP, single dose. Result: Exhibited a significant hypotensive effect in decreasing blood pressure by about 40-50%.
References	[1]. Hirschhorn R, et al. Increased excretion of modified adenine nucleosides by children with adenosine deaminase deficiency. Pediatr Res. 1982 May;16(5):362-9. [2]. Yamada T, et al. Naturally occurring 2'-O-methylpurine nucleosides with hypotensive properties. Cell Mol Life Sci. 1998 Feb;54(2):125-8.

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	26-36
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2934999090

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%