Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Flavone, 3-hydroxy-4',5,7-trimethoxy-

3-Hydroxy-5,7,4′-trimethoxyflavone is a flavonol can be isolated from Cucubalus baccifer (L.)[1].

  • CAS Number: 1098-92-6
  • MF: C18H16O6
  • MW: 328.32
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 529.6±50.0 °C at 760 mmHg
  • Melting Point: 150-153℃
  • Flash Point: 194.3±23.6 °C

Endoproteinase Lys-C

Endoproteinase Lys-C is a protease that cleaves proteins on the C-terminal side of lysine residues and is commonly used for protein sequencing[1].

  • CAS Number: 72561-05-8
  • MF: C30H27N3O5
  • MW: 509.552
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 781.9±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 426.7±32.9 °C

Astraisoflavan-7-O-β-D-glucoside

Astraganoside, an isoflavane compound, isolated from the roots of Astragalus membranaceus (known as ‘‘Huangqi’’)[1].

  • CAS Number: 1011711-05-9
  • MF: C23H28O11
  • MW: 480.46
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 674.4±55.0 °C(Predicted)
  • Melting Point: N/A
  • Flash Point: N/A

Maculosin

Maculosin is a host-specific phytotoxin for spotted knapweed from Alternaria alternata. Maculosin is a quorum-sensing molecule involved in cell-cell communication by Pseudomonas aeruginosa. Maculosin also acts as a signaling molecule regulating virulence gene expression in Lactobacillus reuteri. Maculosin shows antioxidant, anti-cancer and non-toxicity properties. Maculosin shows cytotoxic activity against the human liver cancer cell lines, with an IC50 of 48.90 µg/mL[1][2][3].

  • CAS Number: 4549-02-4
  • MF: C14H16N2O3
  • MW: 260.29
  • Catalog: Cancer
  • Density: 1.36g/cm3
  • Boiling Point: 581.4ºC at 760mmHg
  • Melting Point: 156-159 °C
  • Flash Point: 305.4ºC

(Glu24)-Glucagon (1-29) (human, rat, porcine) trifluoroacetate salt

(Glu24)-Glucagon (1-29) (human, rat, porcine) is a fragment of glucagon.

  • CAS Number: 308356-99-2
  • MF: C153H224N42O50S
  • MW: 3483.73
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-D-Lys-OH

(((9H-Fluoren-9-yl)methoxy)carbonyl)-D-lysine is a lysine derivative[1].

  • CAS Number: 110990-08-4
  • MF: C21H24N2O4
  • MW: 368.42600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Condurango glycoside E0

Condurango glycoside E0 is a glycoside that can be isolated from Marsdema cundurango[1].

  • CAS Number: 115784-08-2
  • MF: C59H86O23
  • MW: 1163.30
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-Hydroxy-2,4,6-triiodobenzoic acid

HTBA(3-Hydroxy-2,4,6-triiodobenzoic acid) for your research needs.Off-white to yellow powder.

  • CAS Number: 53279-72-4
  • MF: C7H3I3O3
  • MW: 515.810
  • Catalog: Biochemical Assay Reagents
  • Density: 3.1±0.1 g/cm3
  • Boiling Point: 389.2±42.0 °C at 760 mmHg
  • Melting Point: 211-215°C
  • Flash Point: 189.2±27.9 °C

ML390

ML390 exerts its potent differentiation effect on multiple leukemia models. ML390 will offer insight into the mechanism of overcoming differentiation arrest, and will translate into a starting point for a much-needed new and potent treatment for patients with acute myeloid leukemia.

  • CAS Number: 2029049-79-2
  • MF: C21H21F3N2O3
  • MW: 406.40
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Raludotatug

Raludotatug is a humanized immunoglobulin G1-kappa, anti-CDH6 monoclonal antibody. Raludotatug is an antineoplastic[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Bragsin2

Bragsin2 is a potent, selective and noncompetitive nucleotide exchange factor BRAG2 inhibitor, with an IC50 of 3 μM. Bragsin2 binds at the interface between the PH domain of BRAG2 and the lipid bilayer, leads BRAG2 unable to activate lipidated Arf GTPase. Bragsin2 affects breast cancer stem cells[1].

  • CAS Number: 342795-08-8
  • MF: C11H6F3NO5
  • MW: 289.16
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Benzenesulfonic acid,5-chloro-3-[2-(2,4-dihydroxyphenyl)diazenyl]-2-hydroxy-

Lumogallion is a highly sensitive fluorescent reagent for the detection of aluminum, gallium and other metals. Lumogallion has an excitation wavelength of 490 nm and an emission spectrum in the range of 520 nm to 650 nm, with a peak near 580 nm[1][2].

  • CAS Number: 4386-25-8
  • MF: C12H9ClN2O6S
  • MW: 344.72800
  • Catalog: Others
  • Density: 1.75g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

GLYCOLITHOCHOLIC ACID SODIUM SALT

Glycolithocholic acid sodium is the sodium salt of Glycolithocholic acid. Glycolithocholic acid is a glycine-conjugated secondary bile acid. Glycolithocholic acid can be used to diagnose ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH) and primary sclerosing cholangitis (PSC)[1][2].

  • CAS Number: 24404-83-9
  • MF: C26H42NNaO4
  • MW: 455.60600
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: 619.7ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 328.6ºC

3,5-Difluorophenylalanine

3,5-Difluoro-DL-phenylalanine is a phenylalanine derivative that can be used for amino acids synthesis[1].

  • CAS Number: 32133-37-2
  • MF: C9H9F2NO2
  • MW: 201.170
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 295.1±40.0 °C at 760 mmHg
  • Melting Point: 269.5-273.5ºC(lit.)
  • Flash Point: 132.3±27.3 °C

trans-Communic acid

trans-Communic acid is a diterpenoid. trans-Communic acid can be isolated from ethyl acetate extract of young cones of hinoki (Chamaecyparis obtusa Endl.)[1].

  • CAS Number: 10178-32-2
  • MF: C20H30O2
  • MW: 302.451
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 414.0±34.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 199.8±20.3 °C

Isochandalone

Isochandalone is a new isoflavone isolated from the methanol extractives from white lupin (cv. Kievskij Mutant) roots[1].

  • CAS Number: 121747-90-8
  • MF: C25H24O5
  • MW: 404.46
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 607.7±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 209.2±25.0 °C

3-(Trifluoromethyl)phenol-d4

3-(Trifluoromethyl)phenol-d4 is the deuterium labeled 3-(Trifluoromethyl)phenol[1].

  • CAS Number: 1219798-47-6
  • MF: C7HD4F3O
  • MW: 166.13
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(Val438)-Tyrosinase (432-444) (human) acetate salt

SYLQDSVPDSFQD, anchor-modified for high-affinity binding to DR4, is a DR4-restricted MHC class II peptide Tyrosinase[1].

  • CAS Number: 320341-56-8
  • MF: C65H93N15O26
  • MW: 1500.519
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 1559.9±75.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 897.2±37.1 °C

FR054

FR054 is an inhibitor of the HBP enzyme PGM3, with a remarkable anti-breast cancer effect[1].

  • CAS Number: 35954-65-5
  • MF: C14H19NO8
  • MW: 329.30
  • Catalog: Cancer
  • Density: 1.45±0.1 g/cm3(Predicted)
  • Boiling Point: 416.7±45.0 °C(Predicted)
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-L-photo-methionine

Fmoc-L-photo-methionine is a Methionine (HY-13694) derivative[1].

  • CAS Number: 945859-89-2
  • MF: C21H21N3O4
  • MW: 379.41
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

24RBPyBC

24RBPyBC is a dinucleating macrocyclic ligand, it contains phenolate pyridine, bipyridine, and amino groups form dinuclear Fe(II) and Fe(III) complexes[1][2].

  • CAS Number: 185675-92-7
  • MF: C32H38N6O2
  • MW: 538.68
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A
  • CAS Number: 1059182-23-8
  • MF: C28H30O11
  • MW: 542.53
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Scytonemin

Scytonemin is an ultraviolet sunscreen pigment, that can be isolated from the sheaths of cyanobacteria. Scytonemin displays multiple roles, functioning as a potent UV sunscreen and antioxidant molecules, and can be exploited in cosmetic and other industries for the development of new cosmeceuticals[1].

  • CAS Number: 152075-98-4
  • MF: C36H20N2O4
  • MW: 544.55500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

11-Hydroxygelsenicine

11-Hydroxygelsenicine is a 11-hydroxy-substituted gelsedine-type indole alkaloid compound isolated from the EtOH extract of the stems of Gelsemium elegans[1].

  • CAS Number: 1195760-68-9
  • MF: C19H22N2O4
  • MW: 342.39
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 525.4±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 271.5±32.9 °C

10-O-trans-p-methoxycinnamoyl-catalpol

10-O-Trans-p-methoxycinnamoylcatalpol has antioxidant activity with the IC50 value of 0.37 μM/mL in DPPH free radical scavenging assay[1][2].

  • CAS Number: 201605-27-8
  • MF: C25H30O12
  • MW: 522.50
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Acarbose sulfate

Acarbose sulfate is an inhibitor of alpha glucosidase, an anti-diabetic drug.

  • CAS Number: 1221158-13-9
  • MF: C25H45NO22S
  • MW: 743.68
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1,3-Bis[(2H5)phenyl]urea

1,3-Diphenylurea-d10 is the deuterium labeled 1,3-Diphenylurea[1].

  • CAS Number: 108009-46-7
  • MF: C13H2D10N2O
  • MW: 222.309
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 262.0±9.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 91.1±18.9 °C

8-Hydroxypinoresinol4,4'-di-O-β-D-glucopyranoside

8-Hydroxypinoresinol4,4'-di-O-β-D-glucopyranoside (Compound 7) is a compound derived from roots and rhizomes. 8-Hydroxypinoresinol4,4'-di-O-β-D-glucopyranoside could prevent neurotoxicity in PC12 cells[1].

  • CAS Number: 112747-99-6
  • MF: C32H42O17
  • MW: 698.67
  • Catalog: Neurological Disease
  • Density: 1.561±0.06 g/cm3(Predicted)
  • Boiling Point: 955.8±65.0 °C(Predicted)
  • Melting Point: N/A
  • Flash Point: N/A

Licochalcone C

Licochalcone C could inhibit α-glucosidase, with IC50s of <100 nM and 92.43 μM for α-glucosidase and protein tyrosine phosphatase 1B (PTP1B), respectively.

  • CAS Number: 144506-14-9
  • MF: C21H22O4
  • MW: 338.397
  • Catalog: Metabolic Disease
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 536.1±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 188.4±23.6 °C

3-O-Methyl-N-acetyl-D-glucosamine

3-O-Methyl-N-acetyl-D-glucosamine is a potent inhibitor of N-acetylglucosamine kinase. 3-O-Methyl-N-acetyl-D-glucosamine potently inhibits glucose phosphorylation by N-acetylglucosamine kinase whereas glucokinase is not at all affected by this hexosamine[1].

  • CAS Number: 94825-74-8
  • MF: C9H17NO6
  • MW: 235.23400
  • Catalog: Metabolic Disease
  • Density: 1.368g/cm3
  • Boiling Point: 542.355ºC at 760 mmHg
  • Melting Point: 189-191ºC
  • Flash Point: 281.806ºC