791840-86-3

791840-86-3 structure

Name: NLRP3/AIM2-IN-2
Chemical Name: NLRP3/AIM2-IN-2
CAS Number: 791840-86-3
Molecular Formula: C₁₅H₁₅NO₃
Molecular Weight: 257.28
Catalog: Research Areas Inflammation/Immunology
Create Date: 2022-04-03 17:10:04
Modify Date: 2024-01-04 18:24:38
NLRP3 / aim2-in-2 is a new potent inhibitor with different species-specific effects on NLRP3 and aim2 inflammasome dependent cell death. Its < b > IC < sub > 50 < / sub > < / b > value is 0.2392 ± 0.0233 μ M。

Name	NLRP3/AIM2-IN-2

Description	NLRP3 / aim2-in-2 is a new potent inhibitor with different species-specific effects on NLRP3 and aim2 inflammasome dependent cell death. Its < b > IC < sub > 50 < / sub > < / b > value is 0.2392 ± 0.0233 μ M。
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
Target	NLRP3 and AIM2:0.2392±0.0 μM (IC50)
References	[1]. Jiao Y, et al. Discovery of a novel and potent inhibitor with differential species-specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis. Eur J Med Chem. 2022 Feb 11;232:114194.