150322-05-7

150322-05-7 structure

Name: 5-Carboxytetramethylrhodamine
Chemical Name: 3',6'-bis(dimethylamino)-3-oxospiro[2-benzofuran-1,9'-xanthene]-5-carboxylic acid
CAS Number: 150322-05-7
Molecular Formula: C₂₅H₂₂N₂O₅
Molecular Weight: 430.453
Catalog: Research Areas Others
Create Date: 2018-07-07 13:06:35
Modify Date: 2025-08-26 14:02:36
5-Carboxytetramethylrhodamine can be used as a fluorescent probe of nucleic acids and proteins. 5-Carboxytetramethylrhodamine displays excitation maxima of 558 nm and an emission maximum of 586 nm[1][2][3].

Name	3',6'-bis(dimethylamino)-3-oxospiro[2-benzofuran-1,9'-xanthene]-5-carboxylic acid
Synonyms	5-carboxy Tamra 5-TAMRA 5-carboxytetramethylrhodamine Xanthylium, 9-(2,4-dicarboxyphenyl)-3,6-bis(dimethylamino)-, inner salt 2-[3,6-Bis(dimethylamino)-9-xantheniumyl]-5-carboxybenzoate

Description	5-Carboxytetramethylrhodamine can be used as a fluorescent probe of nucleic acids and proteins. 5-Carboxytetramethylrhodamine displays excitation maxima of 558 nm and an emission maximum of 586 nm[1][2][3].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Lyu Z, et al. Steric-Free Bioorthogonal Labeling of Acetylation Substrates Based on a Fluorine-Thiol Displacement Reaction. J Am Chem Soc. 2021 Jan 27;143(3):1341-1347. [2]. Bucevičius J, et al. Rhodamine-Hoechst positional isomers for highly efficient staining of heterochromatin. Chem Sci. 2018 Dec 12;10(7):1962-1970. [3]. Lyttle MH, et al. A tetramethyl rhodamine (Tamra) phosphoramidite facilitates solid-phase-supported synthesis of 5'-Tamra DNA. J Org Chem. 2000 Dec 29;65(26):9033-8.

Safety Phrases	22-24/25