868592-56-7

868592-56-7 structure

Name: NIAD-4
Chemical Name: 2-[[5-[5-(4-hydroxyphenyl)thiophen-2-yl]thiophen-2-yl]methylidene]propanedinitrile
CAS Number: 868592-56-7
Molecular Formula: C₁₈H₁₀N₂OS₂
Molecular Weight: 334.41500
Catalog: Research Areas Neurological Disease
Create Date: 2017-03-30 11:12:13
Modify Date: 2025-08-20 18:45:58
NIAD-4 is a fluorophore for optical imaging of amyloid-β (Aβ) in the central nervous system (CNS) for Alzheimer’s disease (AD). NIAD-4 binds to the same Aβ site with the binding affinity (Ki) of 10 nM[1].

Name	2-[[5-[5-(4-hydroxyphenyl)thiophen-2-yl]thiophen-2-yl]methylidene]propanedinitrile
Synonyms	Propanedinitrile,[[5'-(4-hydroxyphenyl)[2,2'-bithiophen]-5-yl]methylene] [[5-(4-Hydroxyphenyl)[2,2-bithiophen]-5-yl]methylene]-propanedinitrile NIAD-4 2-[[5'-(4-Hydroxyphenyl)[2,2'-bithiophen]-5-yl]methylene]propanedinitrile

Description	NIAD-4 is a fluorophore for optical imaging of amyloid-β (Aβ) in the central nervous system (CNS) for Alzheimer’s disease (AD). NIAD-4 binds to the same Aβ site with the binding affinity (Ki) of 10 nM[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. Kenneth T. Cheng, et al. [[5'-(4-Hydroxyphenyl)[2,2’-bithiophen]-5-yl]methylene]-propanedinitrile NIAD-4.