Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

ndepap

4-(4-Diethylaminophenylazo)-1-(4-nitrobenzyl)pyridinium bromide is a very stable compound that can be used in the determination of anionic surfactants[1][2].

  • CAS Number: 75902-86-2
  • MF: C22H24BrN5O2
  • MW: 470.36200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

PGMI-004A

PGMI-004A is a potent phosphoglycerate mutase 1 (PGAM1) inhibitor with an IC50 of 13.1 μM.

  • CAS Number: 1313738-90-7
  • MF: C21H12F3NO6S
  • MW: 463.38300
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cyclo(-D-Leu-D-Pro)

Cyclo(D-Leu-D-Pro) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development[1].

  • CAS Number: 274680-11-4
  • MF: C11H18N2O2
  • MW: 210.27
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Captopril EP Impurity D

Captopril EP Impurity D is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM)[1][2][3].

  • CAS Number: 56970-78-6
  • MF: C4H7BrO2
  • MW: 167.00100
  • Catalog: Others
  • Density: 1.625g/cm3
  • Boiling Point: 230.5ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 93.2ºC

Antofine

(-)-Antofine is an alkaloid, a levorotatory Antofine. Antofine is an antifungal compound[1].

  • CAS Number: 32671-82-2
  • MF: C23H25NO3
  • MW: 363.45
  • Catalog: Infection
  • Density: 1.25±0.1 g/cm3(Predicted)
  • Boiling Point: 542.8±45.0 °C(Predicted)
  • Melting Point: 213-215 °C(Solv: acetone (67-64-1))
  • Flash Point: N/A

Gyrophoric acid

Gyrophoric acid is a good ultraviolet filter in lichen populations. Gyrophoric acid shows DPPH radical scavenging activity with an IC50 value of 105.75 µg/ml[1][2].

  • CAS Number: 548-89-0
  • MF: C24H20O10
  • MW: 468.410
  • Catalog: Cancer
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 693.9±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 238.5±25.0 °C

1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d74

1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d74 is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-gly

  • CAS Number: 326495-38-9
  • MF: C44H14D74NO8P
  • MW: 864.60
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Iriflophenone

Iriflophenone, isolated from Aquilaria sinensis, stimulates MCF-7 and T-47D human breast cancer cells proliferation[1][2].

  • CAS Number: 52591-10-3
  • MF: C13H10O5
  • MW: 246.215
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 482.4±33.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 259.6±21.9 °C

7-Deaza-7-Iodo-2'-deoxyguanosine

7-Iodo-7-deaza-2'-deoxyguanosine (7-Deaza-7-Iodo-2'-deoxyguanosine) is a deoxyguanosine derivative that can be used in DNA synthesis and sequencing reactions[1].

  • CAS Number: 172163-62-1
  • MF: C11H13IN4O4
  • MW: 392.150
  • Catalog: Others
  • Density: 2.5±0.1 g/cm3
  • Boiling Point: 679.9±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 365.0±34.3 °C

Glyoxalase I inhibitor 7

Glyoxalase I inhibitor 7 (Compound 6) is a glyoxalase I (Glo-I) inhibitor with an IC50 of 3.65 μM. Glyoxalase I inhibitor 7 can be used as anticancer agent[1].

  • CAS Number: 2455508-31-1
  • MF: C17H16N4O3S
  • MW: 356.40
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

TNP 470

TNP-470 is a methionine aminopeptidase-2 inhibitor and also an angiogenesis inhibitor.

  • CAS Number: 129298-91-5
  • MF: C19H28ClNO6
  • MW: 401.882
  • Catalog: Cancer
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Galgravin

Galgravin is an active compound in Nectandra megapotamica, with anti-inflammatory activity. Galgravin displays in vitro cytotoxic activity and induce apoptosis in leukemia cells[1][2].

  • CAS Number: 528-63-2
  • MF: C22H28O5
  • MW: 372.45500
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Tau Peptide (277-291) trifluoroacetate salt

Tau Peptide (277-291) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development[1].

  • CAS Number: 330456-40-1
  • MF: C73H131N21O23S
  • MW: 1703.01
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 1973.2±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 1147.2±34.3 °C

1-Oleoyl lysophosphatidic acid sodium salt

(Rac)-1-Oleoyl lysophosphatidic acid ((Rac)-1-Oleoyl-sn-glycero-3-phosphate) sodium is the racemic isomer of 1-Oleoyl lysophosphatidic acid sodium (HY-107614)[1].

  • CAS Number: 22556-62-3
  • MF: C21H40NaO7P
  • MW: 458.502
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: 581.5ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 305.5ºC

Dipsacoside B

Dipsacoside B is a major bioactive saponin, which can be used as a marker.

  • CAS Number: 33289-85-9
  • MF: C53H86O22
  • MW: 1075.237
  • Catalog: Inflammation/Immunology
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Phenol,2-(1,3,4-oxadiazol-2-yl)-

Fenadiazole acts as a central nervous system agent to manage insomnia and dreaminess[1].

  • CAS Number: 1008-65-7
  • MF: C8H6N2O2
  • MW: 162.14500
  • Catalog: Neurological Disease
  • Density: 1.38g/cm3
  • Boiling Point: 267.1ºC at 760mmHg
  • Melting Point: 108ºC
  • Flash Point: 115.3ºC

C12 NBD Lactosylceramide (d18:1/12:0)

C12 NBD Lactosylceramide is a derivative of Lactosylceramide labeled with a C12 NBD fluorescent group. C12 NBD Lactosylceramide can be used to identify Lactosylceramides[1].

  • CAS Number: 474943-06-1
  • MF: C48H81N5O16
  • MW: 984.181
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Z-Gly-OSu

Z-Gly-Osu is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 2899-60-7
  • MF: C14H14N2O6
  • MW: 306.271
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: 111-115ºC
  • Flash Point: N/A

Angelol B

Angelol B is a coumarin isolated from the roots of Angelica pubescens f. biserrata, which is passive diffusion as the dominating process in Caco-2 cell monolayer model[1].

  • CAS Number: 83156-04-1
  • MF: C20H24O7
  • MW: 376.40000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Calpain Inhibitor-2

Calpain inhibitors are lipophilic and show moderate to good antiproliferative activity in vitro compared with melanoma cell lines (a-375 and b-16f1) and PC-3 prostate cancer cells. In addition, a member of this group (compound 3) expressed 2 μ M concentration inhibited the invasion of DU-145 cells by 80%.

  • CAS Number: 2413962-65-7
  • MF: C26H33N3O5S
  • MW: 499.62
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Isodemethylwedelolacton

Isodemethylwedelolactone is a kind of procoagulant and haemolytic constituent isolated from Eclipta alba[1].

  • CAS Number: 350681-33-3
  • MF: C15H8O7
  • MW: 300.220
  • Catalog: Others
  • Density: 1.8±0.1 g/cm3
  • Boiling Point: 531.4±35.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 275.2±25.9 °C

(Rac)-Paclobutrazol-15N3

Rac-Paclobutrazol-15N3 is the 15N-labeled Rac-Paclobutrazol[1].

  • CAS Number: 2642083-16-5
  • MF: C15H20Cl15N3O
  • MW: 296.77
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boc-Glu-Lys-Lys-AMC acetate salt

Boc-Glu-Lys-Lys-AMC is a sensitive fluorogenic substrate for urokinase-activated plasmin[1].

  • CAS Number: 73554-85-5
  • MF: C34H52N6O11
  • MW: 720.81000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

GPi 688

GPi688 is a potent and orally active glycogen phosphorylase (GPa) inhibitor with IC50s of 19 nM, 61 nM and 12 nM for human liver GPa, rat liver GPa and human skeletal muscle GPa, respectively[1]. GPi688 can inhibit glucagons-mediated glucose output in rat primary hepatocytes. GPi688 can be used for researching glucagon-mediated hyperglycaemia[2].

  • CAS Number: 918902-32-6
  • MF: C19H18ClN3O4S
  • MW: 419.88
  • Catalog: Metabolic Disease
  • Density: 1.59±0.1 g/cm3 (20 °C, 760 mmHg)
  • Boiling Point: 885.9±65.0 °C (760 mmHg)
  • Melting Point: N/A
  • Flash Point: N/A

11-Anhydro-16-oxoalisol A

16-Oxo-11-anhydroalisol A is a triterpenoid from Alisma orientale[1].

  • CAS Number: 156338-93-1
  • MF: C30H46O5
  • MW: 486.683
  • Catalog: Inflammation/Immunology
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 646.8±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 359.0±28.0 °C

Epiaschantin

Epiaschantin is an anticancer agent. Epiaschantin shows antiproliferative activity[1].

  • CAS Number: 41689-50-3
  • MF: C22H24O7
  • MW: 400.42
  • Catalog: Cancer
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 525.8±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 214.7±30.0 °C

Bromobimane

Bromobimane is essentially nonfluorescent and converts into fluorescent products when reacts with small thiols.

  • CAS Number: 71418-44-5
  • MF: C10H11BrN2O2
  • MW: 271.11100
  • Catalog: Dye Reagents
  • Density: 1.66g/cm3
  • Boiling Point: 327.8ºC at 760 mmHg
  • Melting Point: 152-154ºC
  • Flash Point: 152.1ºC

Alisol A 24-acetate

Alisol A 24-acetate is a natural product.

  • CAS Number: 18674-16-3
  • MF: C32H52O6
  • MW: 532.752
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 641.1±55.0 °C at 760 mmHg
  • Melting Point: 194-196 ºC
  • Flash Point: 196.5±25.0 °C

fmoc-l-3-benzothienylalanine

Fmoc-3-Ala(3-benzothienyl)-OH is an alanine derivative[1].

  • CAS Number: 177966-60-8
  • MF: C26H21NO4S
  • MW: 443.514
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 690.8±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 371.6±31.5 °C

Valpromide

Valpromide is an amide derivative of valproic acid and inhibits human epoxide hydrolase.

  • CAS Number: 2430-27-5
  • MF: C8H17NO
  • MW: 143.22700
  • Catalog: Infection
  • Density: 0.885g/cm3
  • Boiling Point: 274.6ºC at 760mmHg
  • Melting Point: 123-125°C
  • Flash Point: 119.9ºC