Boc-Asp-OMe is an aspartic acid derivative[1].
Pirepemat (IRL752) is a corticalpreferring catecholamine- and cognition-promoting agent. Pirepemat (IRL752) is used for the study of Parkinson's disease[1][2].
Tetrapeptide-4 is a peptide ingredient commonly used in skin care products to reduce wrinkles, strengthen collagen, elastin and fibronectin, and possess powerful anti-aging properties[1].
Kaempferol 3-O-arabinoside is an antioxidant flavonoids isolated from ethyl acetate fraction (EAF) obtained from the leaves of Nectandra hihua. Kaempferol 3-O-arabinoside has good antioxidant capacity[1].
Apelin-12 is one of the most potent C-terminal fragments of the polypeptide that possesses a high affinity to orphan receptor APJ receptor. Apelin-12 is involved in the regulation of body fluid homeostasis and in the central control of feeding. Apelin-12 blocks HIV-1 entry through APJ receptor. Apelin-12 exerts neuroprotective effect[1][2][3].
3,5,7-Trimethoxyflavone, a flavonoid compound, can inhibit the TNF-α-induced high expression and secretion of MMP-1 by cells. 3,5,7-Trimethoxyflavone can be used to ameliorate skin damage[1].
Trometamol is a biologically inert amino alcohol of low toxicity, which buffers carbon dioxide and acids in vitro and in vivo. Trometamol is an effective amine compound for pH control in the physiological range[1].
(2S)-2-[[(tert-Butoxy)carbonyl](methyl)amino]-3-methylbutanoic acid is a valine derivative[1].
Monomethyl auristatin E intermediate-12 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].
(5E,9E,13E)-Teprenone ((5E,9E,13E)-Geranylgeranylacetone) is an isomer of Teprenone with antiulcer activity. (5E,9E,13E)-Teprenone induces transcriptional activation of HSP genes that may increase gastric mucosal defense at conditions of stress[1].
(±)-Sigmoidin A is an active compound. (±)-Sigmoidin A can be used for the research of various biochemical [1].
Norcholic acid is a normal minorbile C23 bile acid having four side chain and exsits in human urine and meconium. Norcholic acid can become prominent under certain pathological conditions. Norcholic acid is efficiently absorbed from intestine and quickly excreted into the bile but not into urine[1].
Momordicoside L is a Cucurbitane Triterpenoid, that can be isolated from the leaves of Momordica charantia. Momordicoside L shows anticancer activity[1].
SHMT-IN-1 (compound (±)-46) is a potent inhibitor of plasmodial serine hydroxymethyltransferase (SHMT). SHMT-IN-1 has antitumor activity[1].
Methyl (R)-2-((tert-butoxycarbonyl)amino)-3-iodopropanoate is an alanine derivative[1].
Loliolide, a Carotenoid Metabolite, is a potential endogenous inducer of herbivore resistance. Loliolide also inhibits the seedling growth.
Heveaflavone is an anticancer and antioxidant agent[1].
Aurantio-obtusin is an anthraquinone isolated from Semen Cassiae, with anti-Inflammatory, anti-oxidative, anti-coagulating and anti-hypertension activities[1][2][3]. Aurantio-obtusin relaxes systemic arteries through endothelial PI3K/AKT/eNOS-dependent signaling pathway in rats, thus acts as a new potential vasodilator[2]. Aurantio-obtusin inhibits allergic responses in IgE-mediated mast cells and anaphylactic models and is potential for treatment for allergy-related diseases[3].
Mebeverine alcohol D5 is the deuterium labeled Mebeverine alcohol, which is a metabolite of Mebeverine.
G-NGA2 N-Glycan is a N-Glycan, and can be used for labeling and modification of proteins.
2,3-Dibromoacrylic acid is dibromo product based on acrylic acid. Acrylic acid is the simplest unsaturated carboxylic acid and can be used as a chemical intermediate.
MLS001006105 is used for biological test against the protein target: lamin isoform A-delta10[1].
Sotigalimab, a CD40 agonistic monoclonal antibody, can be used for the research of metastatic pancreatic adenocarcinoma[1].
SW-034538 is a potent TAOK2 (Thousand-And-One Kinase 2; MAP3K17) inhibitor with IC50 of 300 nM, has cross-reactivity with respect to six of the 45 kinases (Raf1, GSK3β, JNK1, IRAK4, HGK and CDK2).
Poricoic acid A, isolated from Poria cocos, possesses anti-tumor activity[1]. Poricoic acid A enhances melatonin inhibition of AKI-to-CKD transition by regulating Gas6/AxlNFκB/Nrf2 axis[2].
Alefacept (BG 9273) is a human lymphocyte function-associated antigen 3/immunoglobulin 1 fusion protein. Alefacept can be used for the research of chronic plaque psoriasis[1].
Acuminatin is a new bis-phenylpropide can be isolated from Magnolia acuminata L[1].
Necrocide 1 (compound (S)-38) a potent anticancer agent. Necrocide 1 has antiproliferative activity with an IC50 value of 0.48 and 2 nM for MCF-7 and PC3, respectively[1].
Imidacloprid-urea is a metabolite of Imidacloprid. Imidacloprid is an effective and widely used neonicotinoid pesticide to control pests of cereals, vegetables, tea and cotton. Imidacloprid-urea can occupy or block adsorption sites of imidacloprid on soil, potentially affecting the fate, transport, and bioavailability of imidacloprid in the environment[1].
Tanshinoic acid A, a oxidic tanshinone diterpenoid, is a 11,12-seco-tanshinone derivative[1].