Necrocide 1

Modify Date: 2024-09-13 20:44:36

Necrocide 1 structure	Common Name	Necrocide 1
	CAS Number	1247028-61-0	Molecular Weight	365.47
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₇NO₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Necrocide 1

Necrocide 1 (compound (S)-38) a potent anticancer agent. Necrocide 1 has antiproliferative activity with an IC50 value of 0.48 and 2 nM for MCF-7 and PC3, respectively[1].

Name	(3S)-3-cycloheptyl-3-(4-hydroxyphenyl)-6-methoxy-7-methyl-1H-indol-2-one
Synonym	More Synonyms

Description	Necrocide 1 (compound (S)-38) a potent anticancer agent. Necrocide 1 has antiproliferative activity with an IC50 value of 0.48 and 2 nM for MCF-7 and PC3, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Synthesis and Antitumor Effect in Vitro and in Vivo of Substituted 1,3-Dihydroindole-2-onesJ. Med. Chem., Article ASAPDOI: 10.1021/jm100763jPublication Date (Web): September 16, 2010 [2]. Christensen MK, et, al. Synthesis and antitumor effect in vitro and in vivo of substituted 1,3-dihydroindole-2-ones. J Med Chem. 2010 Oct 14;53(19):7140-5.

Description

Necrocide 1 (compound (S)-38) a potent anticancer agent. Necrocide 1 has antiproliferative activity with an IC50 value of 0.48 and 2 nM for MCF-7 and PC3, respectively[1].

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

References

[1]. Synthesis and Antitumor Effect in Vitro and in Vivo of Substituted 1,3-Dihydroindole-2-onesJ. Med. Chem., Article ASAPDOI: 10.1021/jm100763jPublication Date (Web): September 16, 2010

[2]. Christensen MK, et, al. Synthesis and antitumor effect in vitro and in vivo of substituted 1,3-dihydroindole-2-ones. J Med Chem. 2010 Oct 14;53(19):7140-5.

Molecular Formula	C₂₃H₂₇NO₃
Molecular Weight	365.47
Exact Mass	365.19900
PSA	62.05000
LogP	5.00290

2H-Indol-2-one,3-cycloheptyl-1,3-dihydro-3-(4-hydroxyphenyl)-6-methoxy-7-methyl-,(3S)

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Necrocide 1

Use of Necrocide 1

Names

Necrocide 1 Biological Activity

Chemical & Physical Properties

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.