Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

2-Selenouracil

2-Selenouracil is a useful specialized photosensitizer for photodynamical therapy[1].

  • CAS Number: 16724-03-1
  • MF: C4H4N2OSe
  • MW: 176.05500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Tetra-N-acetylchitotetraose

Tetra-N-acetylchitotetraose elicits plant defense systems. Tetra-N-acetylchitotetraose is a component of the hpo-chitoo gosacchaπdes (LCOs) secreted from Rhizobia. Tetra-N-acetylchitotetraose is also a substrate for the Rhizobium leguminosarum nodulation protein NodB, a CO deacetylase[1].

  • CAS Number: 2706-65-2
  • MF: C32H54N4O21
  • MW: 830.78500
  • Catalog: Inflammation/Immunology
  • Density: 1.57g/cm3
  • Boiling Point: 1338.1ºC at 760mmHg
  • Melting Point: >200ºC dec.
  • Flash Point: 763.1ºC

Xanthiazone

Xanthiazone is a thiazinedione[1].

  • CAS Number: 212701-97-8
  • MF: C11H13NO3S
  • MW: 239.291
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 516.6±50.0 °C at 760 mmHg
  • Melting Point: 159-161 °C
  • Flash Point: 266.2±30.1 °C

2-Desoxy-4-epi-pulchellin

2-Desoxy-4-epi-pulchellin (compound 13) is a compound isolated from dichloromethane-soluble portion of Polygonum hydropiper[1].

  • CAS Number: 122872-03-1
  • MF: C15H22O3
  • MW: 250.33
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 408.2±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 171.6±21.5 °C

1,4,5,6-Tetrahydroxy-7-prenylxanthone

1,4,5,6-Tetrahydroxy-7-(3-methylbut-2-enyl)xanthone is a nature product that could be isolated from the stem barks of Garcinia xanthochymus. 1,4,5,6-Tetrahydroxy-7-(3-methylbut-2-enyl)xanthone has antiproliferative active. 1,4,5,6-Tetrahydroxy-7-(3-methylbut-2-enyl)xanthone can be used in research of cancer[1].

  • CAS Number: 1001424-68-5
  • MF: C18H16O6
  • MW: 328.32
  • Catalog: Cancer
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 561.8±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 207.4±23.6 °C

Methylthiomcresol-C4-COOH

Methylthiomcresol-C4-COOH is a hapten[1].

  • CAS Number: 848486-53-3
  • MF: C13H18O3S
  • MW: 254.35
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(R)-Etodolac-D4

(R)-Etodolac-d4 is the deuterium labeled (R)-Etodolac[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

D-Hexamannuronic acid

D-Hexamannuronic acid, an alginate oligomer, is produced by marine brown algae and by a limited range of Gram negative bacteria. D-Hexamannuronic acid can be used for the research of pain and vascular dementia[1][2][3][4].

  • CAS Number: 183668-52-2
  • MF: C36H50O37
  • MW: 1074.76
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Norbiotinamine

Norbiotinamine is an alternative to biotin. Norbiotinamine can be coupled with a carboxylic group of amino acids to give inverse peptides, having the amide linkage oriented in the opposite direction[1].

  • CAS Number: 173401-47-3
  • MF: C9H17N3OS
  • MW: 215.32
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Semastatin 5A.1

Semastatin 5A.1 is an anti-angiogenic 19-amino acid peptides that are derived from proteins containing type I thrombospondin motifs[1].

  • CAS Number: 929555-15-7
  • MF: C85H140N34O25S2
  • MW: 2102.36
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Narirutin

Narirutin, one of the active constituents isolated from Citrus unshiu, has antioxidant and anti-inflammatory activities. Narirutin is a shikimate kinase inhibitor with anti-tubercular potency[1][2].

  • CAS Number: 14259-46-2
  • MF: C27H32O14
  • MW: 580.535
  • Catalog: Inflammation/Immunology
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 924.3±65.0 °C at 760 mmHg
  • Melting Point: 152-190ºC
  • Flash Point: 307.3±27.8 °C

Tasumatrol L

Tasumatrol L (compound 5) is a 21-carbon taxane ester that can be found in Taxus sumatrana[1].

  • CAS Number: 847835-17-0
  • MF: C36H44O15
  • MW: 716.73
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 777.3±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 235.6±26.4 °C

CBR 5884

CBR-5884 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH) with an IC50 of 33 μM.

  • CAS Number: 681159-27-3
  • MF: C14H12N2O4S2
  • MW: 336.386
  • Catalog: Cancer
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 378.1±42.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 182.5±27.9 °C

Cyperenone

Cyperotundone is a sesquiterpene isolated from Nagarmotha (Cyperus rotundus)[1][2].

  • CAS Number: 3466-15-7
  • MF: C15H22O
  • MW: 218.33500
  • Catalog: Others
  • Density: 1.03±0.1 g/cm3
  • Boiling Point: 318.7±9.0℃ at 760 mmHg
  • Melting Point: 48 ºC
  • Flash Point: N/A

benzil-d10

Benzil-d10 is the deuterium labeled Benzil[1].

  • CAS Number: 77092-81-0
  • MF: C14D10O2
  • MW: 220.29000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Arg-Glu-OH

Arg-Glu is a biologically active peptide.

  • CAS Number: 15706-89-5
  • MF: C11H21N5O5
  • MW: 303.31500
  • Catalog: Others
  • Density: 1.54g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

abecomotide

Abecomotide is a biological active peptide. (an immunological agent for active immunization)

  • CAS Number: 907596-50-3
  • MF: C45H79N13O16
  • MW: 1058.19
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 1579.6±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 909.1±34.3 °C

6alpha-Methylprednisolone sodium succinate

6α-Methylprednisolone 21-hemisuccinate sodium salt is a glucocorticoid of slightly longer half-life than that of Prednisolone. It has potential uses in antiinflammatory agents.

  • CAS Number: 2375-03-3
  • MF: C26H33NaO8
  • MW: 496.525
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: 689.6ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 230.7ºC

AP-C3

AP-C3 is a potent inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) with a pIC50 of 6.3. AP-C3 only weakly inhibits cGKII-dependent anion secretion[1].

  • CAS Number: 682795-78-4
  • MF: C22H23N3O4
  • MW: 393.44
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-[3,4-Bis(benzyloxy)phenyl](2H3)ethanone

3′,4′-Dibenzyloxyaceto-phenone-d3 is the deuterium labeled 3′,4′-Dibenzyloxyaceto-phenone[1].

  • CAS Number: 344299-53-2
  • MF: C22H17D3O3
  • MW: 335.411
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 495.0±35.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 245.4±12.4 °C

Dipquo

DIPQUO is an activator of the bone marker alkaline phosphatase (ALP), with an EC50 of 6.27 μM in C2C12 cells. DIPQUO promotes mouse and human osteoblast differentiation via activation of p38 MAPK-β[1].

  • CAS Number: 1269365-82-3
  • MF: C20H17N3O
  • MW: 315.37
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Imexon

Imexon is an iminopyrrolidone aziridine with anti-cancer activity.

  • CAS Number: 59643-91-3
  • MF: C4H5N3O
  • MW: 111.10200
  • Catalog: Cancer
  • Density: 2.26g/cm3
  • Boiling Point: 231.6ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: N/A

Euphoheliosnoid A

Euphoheliosnoid A (Compound 24) is a diterpenoid that can significantly enhance the killing activity of natural killer (NK) cells towards H1299-luci cells and A549-luci cells at the concentration of 2.5 μM[1].

  • CAS Number: 863401-14-3
  • MF: C37H43NO9
  • MW: 645.74
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2'-O-MOE-U

2'-O-MOE-U is an oligonucleotide, can be used for oligonucleotide synthesis[1].

  • CAS Number: 163759-97-5
  • MF: C42H53N4O10P
  • MW: 804.865
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Benzyloxycarbonyl-L-alanine N-hydroxy succinimide ester

Z-Ala-OSu is an alanine derivative[1].

  • CAS Number: 3401-36-3
  • MF: C15H16N2O6
  • MW: 320.297
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: 119-123ºC
  • Flash Point: N/A

Asfotase alfa

Asfotase alfa (ENB-0040) is a bone-targeted genetically engineered glycoprotein. Asfotase alfa increases the survival rate, bone mineralization and bone length and prevents mineralization defects of the feet, rib cage, lower limbs, jaw bones in Akp2−/− knockout mice. Asfotase alfa can be used for the research of perinatal, infantile, and juvenile-onset hypophosphatasia (HPP)[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-Isomangostin

1-Isomangostin is an inhibitor of pancreatic lipase. 1-Isomangostin inhibits porcine pancreatic lipase with an IC50 of 34.5 μM. 1-Isomangostin has anti-obesity activity[1].

  • CAS Number: 19275-44-6
  • MF: C24H26O6
  • MW: 410.46
  • Catalog: Metabolic Disease
  • Density: 1.257g/cm3
  • Boiling Point: 613.9ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 211.5ºC

N-Succinimidyl-S-acetylthioacetate

N-Succinimidyl S-acetylthioacetate (SATA), a protein modification agent, introduces thiol-groups into protein molecules. N-Succinimidyl S-acetylthioacetate adds sulfhydryl groups to proteins and other amine-containing molecules in a protected form[1][2].

  • CAS Number: 76931-93-6
  • MF: C8H9NO5S
  • MW: 231.226
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 337.3±44.0 °C at 760 mmHg
  • Melting Point: 84-89ºC
  • Flash Point: 157.8±28.4 °C

bianfugenine

Dauriporphine, an alkaloid, can be isolated from the vines of Menispermum dauricum DC[1].

  • CAS Number: 88142-60-3
  • MF: C20H17NO5
  • MW: 351.35300
  • Catalog: Others
  • Density: 1.31g/cm3
  • Boiling Point: 602.8ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 318.3ºC

Veratrosine

Veratramine is a steroidal alkaloid extracted from the roots and rhizomes of Veratrum californicum[1].

  • CAS Number: 475-00-3
  • MF: C33H49NO7
  • MW: 571.74500
  • Catalog: Others
  • Density: 1.29 g/cm3
  • Boiling Point: 740.7±60.0℃ at 760 mmHg
  • Melting Point: 237.8-239.7℃
  • Flash Point: N/A