Ganoderic acid A structure
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Common Name | Ganoderic acid A | ||
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CAS Number | 81907-62-2 | Molecular Weight | 516.67 | |
Density | 1.2±0.1 g/cm3 | Boiling Point | 700.3±60.0 °C at 760 mmHg | |
Molecular Formula | C30H44O7 | Melting Point | N/A | |
MSDS | USA | Flash Point | 391.3±29.4 °C |
Use of Ganoderic acid AGanoderic acid can Inhibitt of the JAK-STAT3 signaling pathway, also inhibit proliferation, viability, ROS.In vitro: A lower doses of Ganoderic acid enhance HLA class II-mediated antigen presentation and CD4+ T cell recognition of lymphoma. [1] ganoderic acid A promots cisplatin-induced cell death by enhancing the sensitivity of HepG2 cells to cisplatin mainly via the signal transducer and activator of transcription 3 suppression. [2] Ganoderic acid A inhibits proliferation, viability, ROS, DPPH, and analyzed the expression of SOD1, SOD2, and SOD3 by Real time PCR in a PC-3 cell in a dose-dependent manner.[3] GA-A effectively inhibites the proliferation of human osteosarcoma HOS and MG-63 cells in a dose-dependent manner, and induced obvious cell apoptosis in both cells.[4]In vivo: Ganoderic acid -treatment significantly prolonged survival of EL4 challenged mice and decreased tumor metastasis to the liver.[1] |
Name | (2R,6R)-6-[(5R,7S,10S,13R,14R,15S,17R)-7,15-dihydroxy-4,4,10,13,14-pentamethyl-3,11-dioxo-2,5,6,7,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoic acid |
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Synonym | More Synonyms |
Description | Ganoderic acid can Inhibitt of the JAK-STAT3 signaling pathway, also inhibit proliferation, viability, ROS.In vitro: A lower doses of Ganoderic acid enhance HLA class II-mediated antigen presentation and CD4+ T cell recognition of lymphoma. [1] ganoderic acid A promots cisplatin-induced cell death by enhancing the sensitivity of HepG2 cells to cisplatin mainly via the signal transducer and activator of transcription 3 suppression. [2] Ganoderic acid A inhibits proliferation, viability, ROS, DPPH, and analyzed the expression of SOD1, SOD2, and SOD3 by Real time PCR in a PC-3 cell in a dose-dependent manner.[3] GA-A effectively inhibites the proliferation of human osteosarcoma HOS and MG-63 cells in a dose-dependent manner, and induced obvious cell apoptosis in both cells.[4]In vivo: Ganoderic acid -treatment significantly prolonged survival of EL4 challenged mice and decreased tumor metastasis to the liver.[1] |
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Related Catalog | |
References |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 700.3±60.0 °C at 760 mmHg |
Molecular Formula | C30H44O7 |
Molecular Weight | 516.67 |
Flash Point | 391.3±29.4 °C |
PSA | 128.97000 |
LogP | 2.15 |
Vapour Pressure | 0.0±5.0 mmHg at 25°C |
Index of Refraction | 1.575 |
Storage condition | -20°C |
Safety Phrases | 24/25 |
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RIDADR | NONH for all modes of transport |
ganoderic acid A |
(7β,15α,20E)-7,15-Dihydroxy-3,11,23-trioxolanosta-8,20(22)-dien-26-oic acid |
Ganoderic acid |
Lanosta-8,20(22)-dien-26-oic acid, 7,15-dihydroxy-3,11,23-trioxo-, (7β,15α,20E)- |