21668-77-9
21668-77-9 structure
- Name: eprodisate
- Chemical Name: propane-1,3-disulfonic acid
- CAS Number: 21668-77-9
- Molecular Formula: C3H8O6S2
- Molecular Weight: 204.222
- Catalog: Chemical reagent Organic reagent Sulfonate/sulfinate
- Create Date: 2018-07-23 18:10:05
- Modify Date: 2024-01-02 19:29:04
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Eprodisate is a new compound designed to interfere with interactions between amyloidogenic proteins and glycosaminoglycans and thereby inhibit polymerization of amyloid fibrils and deposition of the fibrils in tissues[1]. Eprodisate slow the progression of AA amyloidosis-related renal disease and has possible applicability to other types of amyloidosis[2].
| Name | propane-1,3-disulfonic acid |
|---|---|
| Synonyms |
propanedisulfonate
Propane-1,3-disulfonate Eprodisate [INN] eprodisate 1.3-propanesultone 1,3-propane sulfone Propane-1,3-disulfonic acid 1,3-propanedisulphonic acid 1,3-Propanedisulfonic acid 1,3-Propanedisulfonicacid UNII-6QFP76V7S7 P8454_ALDRICH 1,3-Propane disulfonate MFCD00191483 |
| Description | Eprodisate is a new compound designed to interfere with interactions between amyloidogenic proteins and glycosaminoglycans and thereby inhibit polymerization of amyloid fibrils and deposition of the fibrils in tissues[1]. Eprodisate slow the progression of AA amyloidosis-related renal disease and has possible applicability to other types of amyloidosis[2]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.8±0.1 g/cm3 |
|---|---|
| Melting Point | 120-124ºC |
| Molecular Formula | C3H8O6S2 |
| Molecular Weight | 204.222 |
| Exact Mass | 203.976227 |
| PSA | 125.50000 |
| LogP | -3.47 |
| Index of Refraction | 1.549 |
| Symbol |
GHS05, GHS07 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H302 + H312 + H332-H314 |
| Precautionary Statements | P280-P305 + P351 + P338-P310 |
| Hazard Codes | Xi: Irritant;C: Corrosive; |
| Risk Phrases | 36/37/38-34-20/21/22 |
| Safety Phrases | S26-S36-S45-S36/37/39-S27 |
| RIDADR | 3265 |
| WGK Germany | 3 |
| Packaging Group | III |
| Hazard Class | 8 |
| HS Code | 2904100000 |
|
~88%
21668-77-9 |
| Literature: Tetrahedron Letters, , vol. 48, # 46 p. 8178 - 8181 |
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21668-77-9 |
| Literature: Journal of the American Chemical Society, , vol. 67, p. 1578,1580 Journal of the American Chemical Society, , vol. 58, p. 488 |
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21668-77-9 |
| Literature: Chemische Berichte, , vol. 91, p. 1512,1514 |
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21668-77-9 |
| Literature: Kogyo Kagaku Zasshi, , vol. 59, p. 221,223 Chem.Abstr., , p. 10362 |
| Precursor 4 | |
|---|---|
| DownStream 3 | |
| HS Code | 2904100000 |
|---|---|
| Summary | 2904100000 derivatives containing only sulpho groups, their salts and ethyl esters。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |